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26.04.2023 | Sleep Breathing Physiology and Disorders • Original Article

Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects

verfasst von: Gülsüm Bingöl, Fulya Avcı Demir, Emre Özmen, Serkan Ünlü, Özge Özden, Ferit Böyük, Hasim Tüner, Muharrem Nasifov, Volkan Çamkıran, İbrahim Sarı

Erschienen in: Sleep and Breathing | Ausgabe 6/2023

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Abstract

Objectives

Sleep deprivation (SD) has been found to be associated with an increased incidence of adverse cardiovascular disease (CVD) events. The aim of this study was to investigate whether or not acute SD has a pathological effect on the geometry and the systolic and diastolic functions of the right and left heart chambers by standard transthoracic echocardiography (TTE) and speckle tracking echocardiography (STE) in healthy individuals with acute SD.

Methods

Nurses with no history of acute or chronic diseases underwent TTE and STE after working a night shift, a sleepless period of 24 h and 7 days of normal sleep after the night shift. Measurements of TTE and STE taken in the rested state were compared with those taken after 24 h of sleep deprivation.

Results

The study included 52 nurses (38 women, 73%). The mean age of the study population was 27.9 ± 7.4 years and mean BMI was 24.1 ± 4.8. Left atrial reservoir (51.5 ± 13.5 vs. 45.4 ± 10; p = 0.004), conduit (− 37.3 ± 11.3 vs. − 33.6 ± 7.9; p = 0.01), left ventricular global longitudinal strain (LVGLS, − 22.6 ± 2.4 vs. − 21.3 ± 2.4; p = 0.001), right ventricular global longitudinal strain (RVGLS, − 25.3 ± 3.7 vs. − 23.5 ± 3.9; p = 0.005) and right ventricular free wall longitudinal strain (RVFWSL, − 29.1 ± 4.2 vs. − 27 ± 4.5; p = 0.001) were impaired significantly after SD.

Conclusion

This study is the first to investigate the negative effects of acute sleep deprivation on LV and RV strain in healthy adults using echocardiography. The findings showed that acute sleep deprivation leads to deterioration in function of both ventricles and left atrium. Speckle tracking echocardiography demonstrated subclinical diminished heart function.

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Titel: Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects
verfasst von: Gülsüm Bingöl
Fulya Avcı Demir
Emre Özmen
Serkan Ünlü
Özge Özden
Ferit Böyük
Hasim Tüner
Muharrem Nasifov
Volkan Çamkıran
İbrahim Sarı
Publikationsdatum: 26.04.2023
Verlag: Springer International Publishing
Erschienen in: Sleep and Breathing / Ausgabe 6/2023
Print ISSN: 1520-9512
Elektronische ISSN: 1522-1709
DOI: https://doi.org/10.1007/s11325-023-02837-w

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Acute sleep deprivation: impairment of biventricular function assesed by speckle tracking echocardiography in healthy subjects