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Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery 3/2023

14.02.2023 | Original Article

An Exposition on Surgical Experiences in Identification, Exposure, and Injuries of Recurrent Laryngeal Nerve (RLN) During Thyroid Operations: Gleanings, Narrative, and the Reflections

verfasst von: Apoorva Kumar Pandey, Arvind Varma, Chetan Bansal, Aparna Bhardwaj

Erschienen in: Indian Journal of Otolaryngology and Head & Neck Surgery | Ausgabe 3/2023

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Abstract

Background: Identifying and preserving the recurrent laryngeal nerve (RLN) is of paramount importance during thyroid surgeries. Iatrogenic injuries to RLN (RLNI) are considered one of the most serious and feared complications of thyroidectomies. Surgically, there are four routes/approaches (lateral, inferior, superior, and medial) for localizing and identifying the RLN. This study aims to estimate the incidence of RLNI in the context of various approaches taken intra-operatively for nerve localization and identification. Materials and Methods: This retrospective analytical study included 54 cases of thyroidectomies operated for various benign and malignant thyroid disorders in a tertiary care center from January 2018 to December 2020. Intraoperative search, identification, and dissection of the nerve were done with superior, inferior, medial, and lateral approaches. The chi-square test and exact test were used to analyze the data and p-value < 0.05 was considered significant. Pre- and post-operative recurrent laryngeal nerve evaluation was done with 90 degrees Hopkins laryngoscope. Results: Overall in this series, the incidence of post-thyroidectomy RLNI was 3.7% and 3.7% for permanent and temporary nerve insults, respectively. Non-recurrent RLN on the right side was identified in one case and extra-laryngeal branching of RLN was identified in two cases. There was no statistically significant difference (p = 0.929) between the different approaches taken and the incidence of RLNI. The type of surgery and pathology also expressed no statistically significant relevance with the incidence of RLNI (p = 0.463 and p = 0.277, respectively). Conclusion: Adoption of a particular surgical approach to localize and identify RLN during thyroid surgery carries no statistically significant difference between RLNI and approaches taken. Meticulous handling and dissection of the tissue in the correct surgical plane are crucial determinants in preventing RLNIs.
Literatur
1.
Zurück zum Zitat Tresallet C, Chigot JP, Menegaux F (2006) How to prevent recurrent nerve palsy during thyroid surgery? Ann Chir 131:149–153PubMed Tresallet C, Chigot JP, Menegaux F (2006) How to prevent recurrent nerve palsy during thyroid surgery? Ann Chir 131:149–153PubMed
2.
Zurück zum Zitat Flynn MB, Lyons KJ, Tarter JW, Ragsdale TL (1994) Local complications after surgical resection for thyroid carcinoma. Am J Surg 168:404–407CrossRefPubMed Flynn MB, Lyons KJ, Tarter JW, Ragsdale TL (1994) Local complications after surgical resection for thyroid carcinoma. Am J Surg 168:404–407CrossRefPubMed
3.
Zurück zum Zitat Rulli F, Ambrogi V, Dionigi G, Amirhassankhani S, Mineo TC, Ottaviani F et al (2014) Meta-analysis of recurrent laryngeal nerve injury in thyroid surgery with or without intra-operative nerve monitoring. Acta Otorhinolaryngol Italica 34:223–229 Rulli F, Ambrogi V, Dionigi G, Amirhassankhani S, Mineo TC, Ottaviani F et al (2014) Meta-analysis of recurrent laryngeal nerve injury in thyroid surgery with or without intra-operative nerve monitoring. Acta Otorhinolaryngol Italica 34:223–229
4.
Zurück zum Zitat Uludag M, Tanal M, Isgor A (2018) A review of methods for the preservation of laryngeal nerves during thyroidectomy. Med Bull Sisli Etfal Hosp 52(2):79–91 Uludag M, Tanal M, Isgor A (2018) A review of methods for the preservation of laryngeal nerves during thyroidectomy. Med Bull Sisli Etfal Hosp 52(2):79–91
5.
Zurück zum Zitat Karamanakos SN, Markou KB, Panagopoulos K et al (2010) Complications and risk factors related to the extent of surgery in thyroidectomy. Results from 2043 procedures. Horm (Athens) 9:318–325CrossRef Karamanakos SN, Markou KB, Panagopoulos K et al (2010) Complications and risk factors related to the extent of surgery in thyroidectomy. Results from 2043 procedures. Horm (Athens) 9:318–325CrossRef
6.
Zurück zum Zitat Fundakowski CE, Hales NW, Agarwal N, Barczynski M, Camacho PM, Hartl DM (2018) Surgical management of the recurrent laryngeal nerve in thyroidectomy: american Head and neck society Consensus statement.Head & Neck;1–13 Fundakowski CE, Hales NW, Agarwal N, Barczynski M, Camacho PM, Hartl DM (2018) Surgical management of the recurrent laryngeal nerve in thyroidectomy: american Head and neck society Consensus statement.Head & Neck;1–13
7.
Zurück zum Zitat Shedd DP, Durham C (1966) Electrical identification of the recurrent laryngeal nerve. Response of the canine larynx to electrical stimulation of the recurrent laryngeal nerve. Ann Surg 163(1):47–50CrossRefPubMedPubMedCentral Shedd DP, Durham C (1966) Electrical identification of the recurrent laryngeal nerve. Response of the canine larynx to electrical stimulation of the recurrent laryngeal nerve. Ann Surg 163(1):47–50CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Randolph GW (2003) Surgical anatomy of the recurrent laryngeal nerve. In: Randolph GW (ed) Ist edition. Surgery of the thyroid and parathyroid glands. PA; Saunders, Philadelphia. pp.300 – 42. Randolph GW (2003) Surgical anatomy of the recurrent laryngeal nerve. In: Randolph GW (ed) Ist edition. Surgery of the thyroid and parathyroid glands. PA; Saunders, Philadelphia. pp.300 – 42.
10.
Zurück zum Zitat Butskiy O, Chang BA, Luu K, Mckenzie RM, Anderson DW (2018) A systematic approach to the recurrent laryngeal nerve dissection at the cricothyroid junction. J Otolaryngol Head Neck Surg 47:57CrossRefPubMedPubMedCentral Butskiy O, Chang BA, Luu K, Mckenzie RM, Anderson DW (2018) A systematic approach to the recurrent laryngeal nerve dissection at the cricothyroid junction. J Otolaryngol Head Neck Surg 47:57CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Nyeki ARN, Njock LR, Miloundja J, Vokwely JEE, Bengono G (2015) ;132:265–269 Nyeki ARN, Njock LR, Miloundja J, Vokwely JEE, Bengono G (2015) ;132:265–269
12.
Zurück zum Zitat Yu RD (2018) Recurrent laryngeal nerve paralysis and hypocalcemia in superior to inferior compared to inferior to superior dissection approaches in thyroidectomy. Philipp Otolaryngol Head Neck Surg 33(2):24–27CrossRef Yu RD (2018) Recurrent laryngeal nerve paralysis and hypocalcemia in superior to inferior compared to inferior to superior dissection approaches in thyroidectomy. Philipp Otolaryngol Head Neck Surg 33(2):24–27CrossRef
13.
Zurück zum Zitat Babu KV, Naresh Kumar S Study on the effect of recurrent laryngeal nerve identification technique in thyroidectomy on recurrent laryngeal nerve paralysis and hypoparathyroidism.Int J Sci Res. 2016Oct; 5(10):469–473 Babu KV, Naresh Kumar S Study on the effect of recurrent laryngeal nerve identification technique in thyroidectomy on recurrent laryngeal nerve paralysis and hypoparathyroidism.Int J Sci Res. 2016Oct; 5(10):469–473
14.
Zurück zum Zitat Lo CY, Kwoh KF, Yuen PW (2000) A prospective evaluation of recurrent laryngeal nerve paralysis during thyroidectomy. Arch Surg 135:204–207CrossRefPubMed Lo CY, Kwoh KF, Yuen PW (2000) A prospective evaluation of recurrent laryngeal nerve paralysis during thyroidectomy. Arch Surg 135:204–207CrossRefPubMed
15.
Zurück zum Zitat Thomusch O, Machens A, Sekulla C et al (2000) Multivariate analysis of risk factors for postoperative complications in benign goitre surgery: prospective multicentre study in Germany. World J Surg 24:1335–1341CrossRefPubMed Thomusch O, Machens A, Sekulla C et al (2000) Multivariate analysis of risk factors for postoperative complications in benign goitre surgery: prospective multicentre study in Germany. World J Surg 24:1335–1341CrossRefPubMed
16.
Zurück zum Zitat Casella C, Pata G, Nascimbeni R, Mittempergher F, Salerni B (2009) Does extra laryngeal branching have an impact on the rate of post-operative transient or permanent recurrent laryngeal nerve palsy? World J Surg 33(2):261–265CrossRefPubMed Casella C, Pata G, Nascimbeni R, Mittempergher F, Salerni B (2009) Does extra laryngeal branching have an impact on the rate of post-operative transient or permanent recurrent laryngeal nerve palsy? World J Surg 33(2):261–265CrossRefPubMed
18.
Zurück zum Zitat Gray SW, Skandalakis JE, Akin JT (1976) Embryological considerations of thyroid surgery: developmental anatomy of the thyroid, parathyroids and the recurrent laryngeal nerve. Am Surg 42:621–628PubMed Gray SW, Skandalakis JE, Akin JT (1976) Embryological considerations of thyroid surgery: developmental anatomy of the thyroid, parathyroids and the recurrent laryngeal nerve. Am Surg 42:621–628PubMed
19.
Zurück zum Zitat Yalexin B (2006) Anatomic configurations of the recurrent laryngeal nerve and inferior thyroid artery. Surgery 139(2):181–187CrossRef Yalexin B (2006) Anatomic configurations of the recurrent laryngeal nerve and inferior thyroid artery. Surgery 139(2):181–187CrossRef
20.
Zurück zum Zitat Hermann M, Alk G, Roka R, Glaser K, Freissmuth M (2002) Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk. Ann Surg 235:261–268CrossRefPubMedPubMedCentral Hermann M, Alk G, Roka R, Glaser K, Freissmuth M (2002) Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk. Ann Surg 235:261–268CrossRefPubMedPubMedCentral
21.
22.
Zurück zum Zitat Dionigi G, Boni L, Rovera F, Rausei S, Castelnuovo P, Dionigi R (2010) Postoperative laryngoscopy in thyroid surgery: proper timing to detect recurrent laryngeal nerve injury. Langenbecks Arch Surg 395:327–331CrossRefPubMed Dionigi G, Boni L, Rovera F, Rausei S, Castelnuovo P, Dionigi R (2010) Postoperative laryngoscopy in thyroid surgery: proper timing to detect recurrent laryngeal nerve injury. Langenbecks Arch Surg 395:327–331CrossRefPubMed
23.
Zurück zum Zitat Joliat GR, Guarnero V, Demartines N, Schweizer V, Matter M (2017) Recurrent laryngeal nerve injury after thyroid and parathyroid surgery. Medicine 96:17e6674CrossRef Joliat GR, Guarnero V, Demartines N, Schweizer V, Matter M (2017) Recurrent laryngeal nerve injury after thyroid and parathyroid surgery. Medicine 96:17e6674CrossRef
24.
Zurück zum Zitat Pandey AK, Maithani T, Agrahari A, Varma A, Bansal C, Bhardwaj A (2015) Post-operative complications of thyroid surgery: a corroborative study with an overview of evolution of thyroid surgery. Int J Head Neck Surg 6(4):149–154CrossRef Pandey AK, Maithani T, Agrahari A, Varma A, Bansal C, Bhardwaj A (2015) Post-operative complications of thyroid surgery: a corroborative study with an overview of evolution of thyroid surgery. Int J Head Neck Surg 6(4):149–154CrossRef
25.
Zurück zum Zitat Gambardella C, Polistena A, Sanguinetti A, Patrone R, Napolitano S, Esposito D et al (2017) Unintentional recurrent laryngeal nerve injuries following thyroidectomy: is it the surgeon who pays the bill? Int J Surg 41:555–559CrossRef Gambardella C, Polistena A, Sanguinetti A, Patrone R, Napolitano S, Esposito D et al (2017) Unintentional recurrent laryngeal nerve injuries following thyroidectomy: is it the surgeon who pays the bill? Int J Surg 41:555–559CrossRef
26.
Zurück zum Zitat Sturniolo G, D’Alia C, Tonante A, Gagliano E et al (1999) The recurrent laryngeal nerve related to thyroid surgery. Am J Surg 177:485–488CrossRefPubMed Sturniolo G, D’Alia C, Tonante A, Gagliano E et al (1999) The recurrent laryngeal nerve related to thyroid surgery. Am J Surg 177:485–488CrossRefPubMed
Metadaten
Titel
An Exposition on Surgical Experiences in Identification, Exposure, and Injuries of Recurrent Laryngeal Nerve (RLN) During Thyroid Operations: Gleanings, Narrative, and the Reflections
verfasst von
Apoorva Kumar Pandey
Arvind Varma
Chetan Bansal
Aparna Bhardwaj
Publikationsdatum
14.02.2023
Verlag
Springer India
Erschienen in
Indian Journal of Otolaryngology and Head & Neck Surgery / Ausgabe 3/2023
Print ISSN: 2231-3796
Elektronische ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-023-03541-7

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