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07.02.2024 | Original Article

Association of low-carbohydrate diet scores and type 2 diabetes in Chinese rural adults: The Henan Rural Cohort Study

verfasst von: Yan Li, Yuqian Li, Chongjian Wang, Zhenxing Mao, Wenqian Huo, Wenguo Xing, Jia Li, Tian yu Yang, Linlin Li

Erschienen in: Endocrine | Ausgabe 2/2024

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Abstract

Purpose

To investigate the association between low-carbohydrate diet scores (LCDs) and the risk of type 2 diabetes in rural China.

Methods

A total of 38,100 adults were included in the Henan Rural Cohort Study. Macronutrient intake was assessed via a validated food-frequency questionnaire to create low-carbohydrate diet (LCD) scores. Multivariate logistic regression models and subgroup analysis were performed to estimate the odds ratio (OR) and 95% confidence interval (95% CI).

Results

After multivariable adjustment, participants with a high total low-carbohydrate diet score have a high risk of T2D (extreme-quartile OR = 1.23, 95% CI: 1.04–1.41; P = 0.007), whereas plant-based LCD score is not related to T2D risk. Among individuals with a BMI < 24 (extreme-quartile OR = 1.22, 95% CI: 1.01–1.47; P < 0.001) or high levels of physical activity (extreme-quartile OR = 1.42, 95% CI: 1.17–1.72; P < 0.001), the animal-based LCD score is positively correlated with the risk of T2D.

Conclusion

Among Chinese rural populations, high-fat-low carbohydrate diet is associated with an increased risk of type 2 diabetes. High intake of animal protein and fat also increases T2D risk in those who are overweight or have high physical activity.

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Titel: Association of low-carbohydrate diet scores and type 2 diabetes in Chinese rural adults: The Henan Rural Cohort Study
verfasst von: Yan Li
Yuqian Li
Chongjian Wang
Zhenxing Mao
Wenqian Huo
Wenguo Xing
Jia Li
Tian yu Yang
Linlin Li
Publikationsdatum: 07.02.2024
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 2/2024
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-023-03602-5

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Association of low-carbohydrate diet scores and type 2 diabetes in Chinese rural adults: The Henan Rural Cohort Study