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12.05.2023 | COHORT UPDATE

Cohort profile update: Tehran cardiometabolic genetic study

verfasst von: Maryam S. Daneshpour, Mahdi Akbarzadeh, Hossein Lanjanian, Bahar Sedaghati-khayat, Kamran Guity, Sajedeh Masjoudi, Asiyeh Sadat Zahedi, Maryam Moazzam-Jazi, Leila Najd Hassan Bonab, Bita Shalbafan, Sara Asgarian, Goodarz Koli Farhood, Niloofar Javanrooh, Maryam Zarkesh, Parisa Riahi, Mohammad Reza Moghaddas, Parvaneh Arbab Dehkordi, Azar Delbarpour Ahmadi, Firoozeh Hosseini, Sara Jalali Farahani, Farzad Hadaegh, Parvin Mirmiran, Fahimeh Ramezani Tehrani, Arash Ghanbarian, Mohammad Sadegh Fallah Mahboob Pasand, Parisa Amiri, Majid Valizadeh, Farhad Hosseipanah, Maryam Tohidi, Asghar Ghasemi, Azita Zadeh-Vakili, Mohammad Piryaei, Shahram Alamdari, Davood Khalili, Amirabbas Momenan, Maryam Barzin, Sirous Zeinali, Mehdi Hedayati, Fereidoun Azizi

Erschienen in: European Journal of Epidemiology | Ausgabe 6/2023

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Abstract

The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from four main ongoing studies in a family-based longitudinal framework. The study's primary goal is to identify the potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. TCGS cohort focuses on cardiovascular, endocrine, metabolic abnormalities, cancers, and some inherited diseases. Since 2017, the TCGS cohort has augmented by encoding all health-related complications, including hospitalization outcomes and self-reports according to ICD11 coding, and verifying consanguineous marriage using genetic markers. This research provides an update on the rationale and design of the study, summarizes its findings, and outlines the objectives for precision medicine.

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Titel: Cohort profile update: Tehran cardiometabolic genetic study
verfasst von: Maryam S. Daneshpour
Mahdi Akbarzadeh
Hossein Lanjanian
Bahar Sedaghati-khayat
Kamran Guity
Sajedeh Masjoudi
Asiyeh Sadat Zahedi
Maryam Moazzam-Jazi
Leila Najd Hassan Bonab
Bita Shalbafan
Sara Asgarian
Goodarz Koli Farhood
Niloofar Javanrooh
Maryam Zarkesh
Parisa Riahi
Mohammad Reza Moghaddas
Parvaneh Arbab Dehkordi
Azar Delbarpour Ahmadi
Firoozeh Hosseini
Sara Jalali Farahani
Farzad Hadaegh
Parvin Mirmiran
Fahimeh Ramezani Tehrani
Arash Ghanbarian
Mohammad Sadegh Fallah Mahboob Pasand
Parisa Amiri
Majid Valizadeh
Farhad Hosseipanah
Maryam Tohidi
Asghar Ghasemi
Azita Zadeh-Vakili
Mohammad Piryaei
Shahram Alamdari
Davood Khalili
Amirabbas Momenan
Maryam Barzin
Sirous Zeinali
Mehdi Hedayati
Fereidoun Azizi
Publikationsdatum: 12.05.2023
Verlag: Springer Netherlands
Erschienen in: European Journal of Epidemiology / Ausgabe 6/2023
Print ISSN: 0393-2990
Elektronische ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-023-01008-1

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Cohort profile update: Tehran cardiometabolic genetic study

Abstract

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

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