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Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie

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20.05.2022 | Original Article

Comparison between microporous and nanoporous orthodontic miniscrews

An experimental study in rabbits

verfasst von: Yueh-Tse Lee, DDS, MS, Eric Jein-Wein Liou, DDS, MS, Sinn-Wen Chen, Ph.D.

Erschienen in: Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie | Ausgabe 1/2024

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Abstract

Purpose

Surface characteristics of orthodontic miniscrews might affect survival rates and removal torque values (RTVs). This experimental study aimed to clarify whether and why a microporous or nanoporous surface promotes higher survival rates and RTVs for orthodontic miniscrews.

Methods

Using a split-leg design, one set each of nonporous (sham control, n = 24) and microporous (control, n = 6), and three sets of nanoporous (experimental, n = 6 per set) miniscrews were implanted in the tibias of 12 New Zealand rabbits and immediately loaded with 1.5 N nickel–titanium coil springs for 12 weeks. The surface morphology, micropores, and nanotube diameters of the miniscrews were examined using scanning electron microscopy and field-emission scanning electron microscopy. The surface composition and thickness were determined using Auger electron spectroscopy. The survival rates and RTVs of each set were assessed.

Results

The nanoporous miniscrews had higher survival rates, RTVs (p < 0.001), and thicker nanotube oxide thicknesses (p < 0.001) than the nonporous and microporous miniscrews. The nonporous and microporous miniscrews had no nanotube structures. The surface oxide composition was titanium dioxide (TiO₂). The threshold RTV, TiO₂ thickness, and nanotube diameter of nanoporous miniscrews needed to promote the experimental survival rate to 100% was determined to be 6.6 ± 0.8 N-cm (p < 0.05), 22.5 ± 4.8 nm (p < 0.05), and 17.6 ± 2.3 nm or above, respectively.

Conclusion

Nanoporous surfaces promoted higher survival rates and RTVs than microporous miniscrews. This could be due to TiO₂ nanotube structures with thicker oxide layers in nanoporous miniscrews.

Melsen B, Laursen MG (2009) Factors in the decision to use skeletal anchorage. In: Nanda R, Uribe FA (eds) Temporary anchorage devices in orthodontics. Mosby, St. Louis, pp 73–89

Melsen B, Costa A (2000) Immediate loading of implants used for orthodontic anchorage. Clin Orthod Res 3:23–28. https://doi.org/10.1034/j.1600-0544.2000.030105.xCrossRefPubMed

Wilmes B, Rademacher C, Olthoff G, Drescher D (2006) Parameters affecting primary stability of orthodontic mini-implants. J Orofac Orthop 67:162–174. https://doi.org/10.1007/s00056-006-0611-zCrossRefPubMed

Park HS, Jeong SH, Kwon OW (2006) Factors affecting the clinical success of screw implants used as orthodontic anchorage. Am J Orthod Dentofacial Orthop 130:18–25. https://doi.org/10.1016/j.ajodo.2004.11.032CrossRefPubMed

Youn JW, Cha JY, Yu HS, Hwang CJ (2014) Biologic evaluation of a hollow-type miniscrew implant: an experimental study in beagles. Am J Orthod Dentofacial Orthop 145:626–637. https://doi.org/10.1016/j.ajodo.2013.12.028CrossRefPubMed

Roberts WE, Huja S, Roberts JA (2004) Bone remodeling: biomechanics, molecular mechanism, and clinical perspectives. Semin Orthod 10:123–161. https://doi.org/10.1053/j.sodo.2004.01.003CrossRef

Serra G, Morais LS, Elias CN, Meyers MA, Andrade L, Müller CA et al (2008) Sequential bone healing of immediately loaded mini-implants. Am J Orthod Dentofacial Orthop 134:44–52. https://doi.org/10.1016/j.ajodo.2006.09.057CrossRefPubMed

Serra G, Morais LS, Elias CN, Meyers MA, Andrade L, Müller CA et al (2010) Sequential bone healing of immediately loaded mini-implants: histomorphometric and fluorescence analysis. Am J Orthod Dentofacial Orthop 137:80–90. https://doi.org/10.1016/j.ajodo.2007.12.035CrossRefPubMed

Zhang L, Zhao Z, Li Y, Wu J, Zheng L, Tang T (2010) Osseointegration of orthodontic micro-screws after immediate and early loading. Angle Orthod 80:354–360. https://doi.org/10.2319/021909-106.1CrossRefPubMedPubMedCentral

10.

Vande Vannet B, Sabzevar MM, Wehrbein H, Asscherickx K (2007) Osseointegration of mini-screws: a histomorphometric evaluation. Eur J Orthod 29:437–442. https://doi.org/10.1093/ejo/cjm078CrossRefPubMed

11.

Jang TH, Park JH, Moon W, Chae JM, Chang NY, Kang KH (2018) Effects of acid etching and calcium chloride immersion on removal torque and bone-cutting ability of orthodontic mini-implants. Am J Orthod Dentofacial Orthop 154:108–114. https://doi.org/10.1016/j.ajodo.2017.10.032CrossRefPubMed

12.

Schätzle M, Männchen R, Zwahlen M, Lang NP (2009) Survival and failure rates of orthodontic temporary anchorage devices: a systematic review. Clin Oral Implants Res 20:1351–1359. https://doi.org/10.1111/j.1600-0501.2009.01754.xCrossRefPubMed

13.

Tsui WK, Chua HD, Cheung LK (2012) Bone anchor systems for orthodontic application: a systematic review. Int J Oral Maxillofac Surg 41:1427–1438. https://doi.org/10.1016/j.ijom.2012.05.011CrossRefPubMed

14.

Liou EJW, Pai BC, Lin JC (2004) Do mini-screws remain stationary under orthodontic forces? Am J Orthod Dentofacial Orthop 126:42–47. https://doi.org/10.1016/j.ajodo.2003.06.018.8CrossRefPubMed

15.

Wang YC, Liou EJW (2008) Comparison of the loading behavior of the self-drilling and pre-drilling mini-screws throughout orthodontic loading. Am J Orthod Dentofacial Orthop 133:38–43. https://doi.org/10.1016/j.ajodo.2006.01.042CrossRefPubMed

16.

Kim SH, Cho JH, Chung KR, Kook YA, Nelson G (2008) Removal torque values of surface-treated mini-implants after loading. Am J Orthod Dentofacial Orthop 134:36–43. https://doi.org/10.1016/j.ajodo.2006.07.038CrossRefPubMed

17.

Kim SH, Lee SJ, Cho IS, Kim SK, Kim TW (2009) Rotational resistance of surface-treated mini-implant. Angle Orthod 79:899–907. https://doi.org/10.2319/090608-466.1CrossRefPubMed

18.

Chang CS, Lee TM, Chang CH, Liu JK (2009) The effect of microrough surface treatment on mini-screws used as orthodontic anchors. Clin Oral Implants Res 20:1178–1184. https://doi.org/10.1111/j.1600-0501.2009.01728.xCrossRefPubMed

19.

Mo SS, Kim SH, Kook YA, Jeong DM, Chung KR, Nelson G (2010) Resistance to immediate orthodontic loading of surface-treated mini-implants. Angle Orthod 80:123–129. https://doi.org/10.2319/030309-123.1CrossRefPubMedPubMedCentral

20.

Choi SH, Cha JY, Joo UH, Hwang CJ (2012) Surface changes of anodic oxidized orthodontic titanium mini-screw. Angle Orthod 82:522–528. https://doi.org/10.2319/071311-448.1CrossRefPubMed

21.

Choi SH, Jang SH, Cha JY, Hwang CJ (2016) Evaluation of the surface characteristics of anodic oxidized mini-screws and their impact on biomechanical stability: An experimental study in beagle dogs. Am J Orthod Dentofacial Orthop 149:31–38. https://doi.org/10.1016/j.ajodo.2015.06.020CrossRefPubMed

22.

Moghaddam SF, Mohammadi A, Behroozian A (2021) The effect of sandblasting and acid etching on survival rate of orthodontic mini-screws: a split-mouth randomized controlled trial. Prog Orthod 22:2. https://doi.org/10.1186/s40510-020-00347-zCrossRefPubMedPubMedCentral

23.

Sul YT, Johansson CB, Petronis S, Krozer A, Jeong Y, Wennerberg A et al (2002) Characteristics of the surface oxides on turned and electrochemically oxidized pure titanium implants up to dielectric breakdown: The oxide thickness, micropore configurations, surface roughness, crystal structure and chemical composition. Biomaterials 23:491–501. https://doi.org/10.1016/s0142-9612(01)00131-4CrossRefPubMed

24.

Larsson C, Thomsen P, Lausmaa J, Rodahl M, Kasemo B, Ericson LE (1994) Bone response to surface modified titanium implants: studies on electropolished implants with different oxide thickness and morphology. Biomaterials 15:1062–1074. https://doi.org/10.1016/0142-9612(94)90092-2CrossRefPubMed

25.

Sul YT, Johansson CB, Jeong Y, Wennerberg A, Albrektsson T (2002) Resonance frequency and removal torque analysis of implants with turned and anodized surface oxides. Clin Oral Implants Res 13:252–259. https://doi.org/10.1034/j.1600-0501.2002.130304.xCrossRefPubMed

26.

Sul YT, Johansson C, Wennerberg A, Cho LR, Chang BS, Albrektsson T (2005) Optimum surface properties of oxidized implants for reinforcement of osseointegration: surface chemistry, oxide thickness, porosity, roughness, and crystal structure. Int J Oral Maxillofac Implants 20:349–359PubMed

27.

Choi JW, Heo SJ, Koak JY, Kim SK, Lim YJ, Kim SH et al (2006) Biological responses of anodized titanium implants under different current voltages. J Oral Rehabil 33:889–897. https://doi.org/10.1111/j.1365-2842.2006.01669.xCrossRefPubMed

28.

Park KH, Heo SJ, Koak JY, Kim SK, Lee JB, Kim SH et al (2007) Osseointegration of anodized titanium implants under different current voltages: a rabbit study. J Oral Rehabil 34:517–527. https://doi.org/10.1111/j.1365-2842.2006.01688.xCrossRefPubMed

29.

Sul YT (2010) Electrochemical growth behavior, surface properties & enhanced bone response TiO₂ nanotubes on implants. Int J Nanomedicine 5:87–100. https://doi.org/10.2147/ijn.s8012CrossRefPubMedPubMedCentral

30.

Jang I, Shim SC, Choi DS, Cha BK, Lee JK, Choe BH et al (2015) Effect of TiO₂ nanotubes arrays on osseointegration of orthodontic miniscrew. Biomed Microdevices 17:76. https://doi.org/10.1007/s10544-015-9986-1CrossRefPubMed

31.

Macak JM, Sirotna K, Schmuki P (2005) Self-organized porous titanium oxide prepared in Na₂SO₄/NaF electrolytes. Electrochim Acta 50:3679–3684. https://doi.org/10.1016/j.electacta.2005.01.014CrossRef

32.

Bestetti M, Franz S, Cuzzolin M, Arosio P, Cavallotti PL (2007) Structure of nanotubular titanium oxide templates prepared by electrochemical anodization in H₂SO₄/HF solutions. Thin Solid Films 515:5253–5258. https://doi.org/10.1016/j.tsf.2006.12.180CrossRef

33.

Wu HJ, Huang LL, Chen SW, Liou EJW, Lee YT (2009) Surface characterization of anodized dental archwires and mini-screws. J Taiwan Inst Chem Eng 40:563–572. https://doi.org/10.1016/j.jtice.2009.03.009CrossRef

34.

Lee K, Mazare A, Schmuki P (2014) One-dimensional titanium dioxide nanomaterials: nanotubes. Chem Rev 114:9385–9454. https://doi.org/10.1021/cr500061mCrossRefPubMed

35.

Paulose M, Prakasam HE, Varghese O, Peng L, Popat K, Mor G et al (2007) TiO₂ nanotube arrays of 1000 μm length by anodization of titanium foil: phenol red diffusion. J Phys Chem C 111:14992–14997. https://doi.org/10.1021/jp075258rCrossRef

36.

Losic D, Aw MS, Santos A, Gulati K, Bariana M (2015) Titania nanotube arrays for local drug delivery: recent advances and perspectives. Expert Opin Drug Deliv 12:103–127. https://doi.org/10.1517/17425247.2014.945418CrossRefPubMed

37.

Yao C, Slamovich EB, Webster TJ (2008) Enhanced osteoblast functions on anodized titanium with nanotube-like structures. J Biomed Mater Res A 85:157–166. https://doi.org/10.1002/jbm.a.31551CrossRefPubMed

38.

Minagar S, Wang J, Berndt CC, Ivanova EP, Wen C (2013) Cell response of anodized nanotubes on titanium and titanium alloys. J Biomed Mater Res A 101:2726–2739. https://doi.org/10.1002/jbm.a.34575CrossRefPubMed

39.

Sato M, Webster TJ (2004) Nanobiotechnology: implications for the future of nanotechnology in orthopedic applications. Expert Rev Med Devices 1:105–114. https://doi.org/10.1586/17434440.1.1.105CrossRefPubMed

40.

Favero LG, Pisoni A, Paganelli C (2007) Removal torque of osseointegrated mini-implants: an in vivo evaluation. Eur J Orthod 29:443–448. https://doi.org/10.1093/ejo/cjm062CrossRefPubMed

41.

ISO 19023 (2018) Dentistry–Orthodontic anchor screws.

42.

Ong JL, Lucas LC (1998) Auger electron spectroscopy and its use for the characterization of titanium and hydroxyapatite surfaces. Biomaterials 19:455–464. https://doi.org/10.1016/S0142-9612(97)00224-XCrossRefPubMed

43.

Chen Y, Kyung HM, Zhao WT, Yu WJ (2009) Critical factors for the success of orthodontic mini-implants: a systemic review. Am J Orthod Dentofacial Orthop 135:284–291. https://doi.org/10.1016/j.ajodo.2007.08.017CrossRefPubMed

44.

Motoyoshi M, Uemura M, Ono A, Okazaki K, Shigeeda T, Shimizue N (2010) Factors affecting the long-term stability of orthodontic mini-implants. Am J Orthod Dentofacial Orthop 137:588.e1–588.e5. https://doi.org/10.1016/j.ajodo.2009.05.019CrossRefPubMed

45.

Al-Thomali Y, Basha S, Mohamed RN (2022) Effect of surface treatment on the mechanical stability of orthodontic mini-screws: a systematic review with meta-analysis. Angle Orthod 97:127–136. https://doi.org/10.2319/020721-111.1CrossRef

46.

Park J, Bauer S, von der Schmuki MKP (2007) Nanosize and vitality: TiO₂ nanotube diameter directs cell fate. Nano Lett 7:1686–1691. https://doi.org/10.1021/nl070678dCrossRefPubMed

47.

Park J, Bauer S, Schlegel KA, Neukam FW, von der Schmuki MKP (2009) TiO₂ nanotube surfaces: 15 nm–An optimal length scale of surface topography for cell adhesion and differentiation. Small 5:666–671. https://doi.org/10.1002/smll.200801476CrossRefPubMed

Titel: Comparison between microporous and nanoporous orthodontic miniscrews
An experimental study in rabbits
verfasst von: Yueh-Tse Lee, DDS, MS
Eric Jein-Wein Liou, DDS, MS
Sinn-Wen Chen, Ph.D.
Publikationsdatum: 20.05.2022
Verlag: Springer Medizin
Erschienen in: Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie / Ausgabe 1/2024
Print ISSN: 1434-5293
Elektronische ISSN: 1615-6714
DOI: https://doi.org/10.1007/s00056-022-00398-3

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Comparison between microporous and nanoporous orthodontic miniscrews

An experimental study in rabbits

Abstract

Purpose

Methods

Results

Conclusion

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Abstract

Purpose

Methods

Results

Conclusion

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