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16.04.2024 | Review

Current Imaging Approaches in Inflammatory Breast Cancer

verfasst von: Miral M. Patel, Huong T. Le-Petross, Megha M. Kapoor, Janet A. Farag, Gary Whitman, Mary S. Guirguis

Erschienen in: Current Breast Cancer Reports

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Abstract

Purpose of Review

Inflammatory breast cancer (IBC) is a rare and aggressive type of breast cancer with a rapid clinical onset and a poor prognosis. The nonspecific clinical criteria have resulted in a difficult and delayed diagnosis of this rare disease. Radiologists’ awareness of the appropriate imaging modalities and features of IBC can improve prompt diagnosis, accurate staging of this aggressive disease, and early detection of distant metastases.

Recent Findings

Diffuse erythema and severe breast edema involving over one-third of the breast may obscure an identifiable mass on mammography and ultrasound (US) in patients with suspected IBC. Due to utilization of contrast, breast magnetic resonance imaging (MRI) allows exquisite details of breast lesions and is a superior diagnostic modality for IBC. Additionally, breast MRI and Fluorodeoxyglucose positron emission tomography computer tomography (FDG PET-CT) have become standard of care in the staging of IBC patients at the time of presentation.

Summary

Clinical presentation combined with mammography, US, and MRI have become standard of care in the diagnosis of IBC. The improved detection and diagnosis using a multimodality approach can contribute towards improved survival. Breast MRI is also beneficial to evaluate treatment response in patients after diagnosis. FDG PET-CT plays a significant role in establishing metastatic disease at the time of initial diagnosis.
Literatur
12.
13.
Zurück zum Zitat Mendelson EB, Böhm-Vélez M, Berg WA, et al. ACR BI-RADS® ultrasound. In: ACR BI-RADS® Atlas, Breast Imaging Reporting and Data System. In:Reston, VA: American College of Radiology. 2013. Mendelson EB, Böhm-Vélez M, Berg WA, et al. ACR BI-RADS® ultrasound. In: ACR BI-RADS® Atlas, Breast Imaging Reporting and Data System. In:Reston, VA: American College of Radiology. 2013.
16.
17.
Zurück zum Zitat Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Merajver SD, et al. A comparison of criteria to identify inflammatory breast cancer cases from medical records and the surveillance, epidemiology and end results data base, 2007–2009. Breast J. 2014;20(2):185–91. https://doi.org/10.1111/tbj.12234.CrossRefPubMed Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Merajver SD, et al. A comparison of criteria to identify inflammatory breast cancer cases from medical records and the surveillance, epidemiology and end results data base, 2007–2009. Breast J. 2014;20(2):185–91. https://​doi.​org/​10.​1111/​tbj.​12234.CrossRefPubMed
18.
Zurück zum Zitat Adeyefa M, Wei W, Yang W, Candelaria R, Hobbs B, Woodward W, Le-Petross, H. Differences in MIPS imaging of inflammatory breast cancer versus non-inflammatory breast cancer. ARRS 2016 Annual Meeting. Abstract 1047, SS22. Adeyefa M, Wei W, Yang W, Candelaria R, Hobbs B, Woodward W, Le-Petross, H. Differences in MIPS imaging of inflammatory breast cancer versus non-inflammatory breast cancer. ARRS 2016 Annual Meeting. Abstract 1047, SS22.
22.
23.
Zurück zum Zitat Wright FC, Zubovits J, Gardner S, Fitzgerald B, Clemons M, Quan ML, et al. Optimal assessment of residual disease after neo-adjuvant therapy for locally advanced and inflammatory breast cancer–clinical examination, mammography, or magnetic resonance imaging? J Surg Oncol. 2010;101(7):604–10. https://doi.org/10.1002/jso.21559.CrossRefPubMed Wright FC, Zubovits J, Gardner S, Fitzgerald B, Clemons M, Quan ML, et al. Optimal assessment of residual disease after neo-adjuvant therapy for locally advanced and inflammatory breast cancer–clinical examination, mammography, or magnetic resonance imaging? J Surg Oncol. 2010;101(7):604–10. https://​doi.​org/​10.​1002/​jso.​21559.CrossRefPubMed
29.
32.
Zurück zum Zitat •• Kida K, Hess KR, Lim B, Iwase T, Chainitikun S, Valero V, et al. Validation of prognostic stage and anatomic stage in the American Joint committee on cancer 8th edition for inflammatory breast cancer. Cancers (Basel). 2020;12(11). https://doi.org/10.3390/cancers12113105. (This study found that the addition of biological factors in the traditional staging system in the AJCC's 8th edition allows more accurate prognostication in IBC patients.) •• Kida K, Hess KR, Lim B, Iwase T, Chainitikun S, Valero V, et al. Validation of prognostic stage and anatomic stage in the American Joint committee on cancer 8th edition for inflammatory breast cancer. Cancers (Basel). 2020;12(11). https://​doi.​org/​10.​3390/​cancers12113105. (This study found that the addition of biological factors in the traditional staging system in the AJCC's 8th edition allows more accurate prognostication in IBC patients.)
34.
Zurück zum Zitat Amin MB, Greene FL, Edge SB, Compton CC, Gershenwald JE, Brookland RK, et al. The eighth edition AJCC cancer staging manual: continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin. 2017;67(2):93–9. https://doi.org/10.3322/caac.21388.CrossRefPubMed Amin MB, Greene FL, Edge SB, Compton CC, Gershenwald JE, Brookland RK, et al. The eighth edition AJCC cancer staging manual: continuing to build a bridge from a population-based to a more “personalized” approach to cancer staging. CA Cancer J Clin. 2017;67(2):93–9. https://​doi.​org/​10.​3322/​caac.​21388.CrossRefPubMed
35.
Zurück zum Zitat •• Postlewait LM, Teshome M, DeSnyder SM, Lim B, Kuerer HM, Bedrosian I, et al. Factors associated with pathological node negativity in inflammatory breast cancer: are there patients who may be candidates for a de-escalation of axillary surgery? Ann Surg Oncol. 2020;27(12):4603–12. https://doi.org/10.1245/s10434-020-08891-y. (This study evaluated the rate of node negativity at final surgery post neoadjuvant chemotherapy for patients with IBC in an attempt to identify factors that can allow for potential less invasive axillary surgery in appropriate IBC patients.)CrossRefPubMed •• Postlewait LM, Teshome M, DeSnyder SM, Lim B, Kuerer HM, Bedrosian I, et al. Factors associated with pathological node negativity in inflammatory breast cancer: are there patients who may be candidates for a de-escalation of axillary surgery? Ann Surg Oncol. 2020;27(12):4603–12. https://​doi.​org/​10.​1245/​s10434-020-08891-y. (This study evaluated the rate of node negativity at final surgery post neoadjuvant chemotherapy for patients with IBC in an attempt to identify factors that can allow for potential less invasive axillary surgery in appropriate IBC patients.)CrossRefPubMed
Metadaten
Titel
Current Imaging Approaches in Inflammatory Breast Cancer
verfasst von
Miral M. Patel
Huong T. Le-Petross
Megha M. Kapoor
Janet A. Farag
Gary Whitman
Mary S. Guirguis
Publikationsdatum
16.04.2024
Verlag
Springer US
Erschienen in
Current Breast Cancer Reports
Print ISSN: 1943-4588
Elektronische ISSN: 1943-4596
DOI
https://doi.org/10.1007/s12609-024-00546-1

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