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Erschienen in: CME 1-2/2017

08.02.2017 | Herzinsuffizienz | CME Fortbildung

Depression und Herzinsuffizienz — doppeltes Risiko?

Diagnostik, prognostische Bedeutung und Therapie einer unterschätzten Komorbidität

verfasst von: Dr. med. J. Wallenborn, Prof. Dr.med. C. E. Angermann

Erschienen in: CME | Ausgabe 1-2/2017

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Zusammenfassung

Herzinsuffizienz und Depression sind Volkskrankheiten von besonderer klinischer und ökonomischer Relevanz. Verglichen mit der Normalbevölkerung findet sich bei Patienten mit Herzinsuffizienz eine komorbide Depression bis zu fünfmal häufiger. Dies hat negative Auswirkungen auf die Morbidität, Mortalität, Lebensqualität und Behandlungskosten. Depressive Symptome überlappen mit denen der Herzinsuffizienz, was die Diagnose erschwert. Wenig aufwendige Screening-Instrumente, z. B. der 2 Item-Gesundheitsfragebogen für Depression, erleichtern im klinischen Alltag die Erkennung. Bisher gibt es keine Evidenz aus randomisierten kontrollierten Studien, dass Antidepressiva bei Herzinsuffizienz Stimmung und Prognose verbessern können, sodass deren Einsatz eine Einzelfallentscheidung bleiben sollte. Durch körperliches Training, kognitive Verhaltenstherapie und multidisziplinäre ganzheitliche Betreuungskonzepte wurden in einzelnen randomisierten Studien depressive Symptome und/oder die Prognose gebessert.
Literatur
1.
Zurück zum Zitat Rutledge T, Reis VA, Linke SE et al (2006) Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol 48(8):1527–1537. doi: 10.1016/j.jacc.2006.06.055CrossRefPubMed Rutledge T, Reis VA, Linke SE et al (2006) Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol 48(8):1527–1537. doi: 10.1016/j.jacc.2006.06.055CrossRefPubMed
2.
Zurück zum Zitat Angermann CE, Gelbrich G, Stork S et al (2011) Somatic correlates of comorbid major depression in patients with systolic heart failure. Int J Cardiol 147(1):66–73. doi: 10.1016/j.ijcard.2009.07.044CrossRefPubMed Angermann CE, Gelbrich G, Stork S et al (2011) Somatic correlates of comorbid major depression in patients with systolic heart failure. Int J Cardiol 147(1):66–73. doi: 10.1016/j.ijcard.2009.07.044CrossRefPubMed
3.
Zurück zum Zitat Faller H, Stork S, Schowalter M et al (2007) Depression and survival in chronic heart failure: Does gender play a role? Eur J Heart Fail 9(10):1018–1023. doi: 10.1016/j.ejheart.2007.06.011CrossRefPubMed Faller H, Stork S, Schowalter M et al (2007) Depression and survival in chronic heart failure: Does gender play a role? Eur J Heart Fail 9(10):1018–1023. doi: 10.1016/j.ejheart.2007.06.011CrossRefPubMed
4.
Zurück zum Zitat Jiang W, Kuchibhatla M, Clary GL et al (2007) Relationship between depressive symptoms and long-term mortality in patients with heart failure. Am Heart J 154(1):102–108. doi: 10.1016/j.ahj.2007.03.043CrossRefPubMed Jiang W, Kuchibhatla M, Clary GL et al (2007) Relationship between depressive symptoms and long-term mortality in patients with heart failure. Am Heart J 154(1):102–108. doi: 10.1016/j.ahj.2007.03.043CrossRefPubMed
5.
Zurück zum Zitat Sherwood A, Blumenthal JA, Trivedi R et al (2007) Relationship of depression to death or hospitalization in patients with heart failure. Arch Intern Med 167(4):367–373. doi: 10.1001/archinte.167.4.367CrossRefPubMed Sherwood A, Blumenthal JA, Trivedi R et al (2007) Relationship of depression to death or hospitalization in patients with heart failure. Arch Intern Med 167(4):367–373. doi: 10.1001/archinte.167.4.367CrossRefPubMed
6.
Zurück zum Zitat Moraska AR, Chamberlain AM, Shah ND et al (2013) Depression, healthcare utilization, and death in heart failure: A community study. Circ Heart Fail 6(3):387. doi: 10.1161/CIRCHEARTFAILURE.112.000118CrossRefPubMedPubMedCentral Moraska AR, Chamberlain AM, Shah ND et al (2013) Depression, healthcare utilization, and death in heart failure: A community study. Circ Heart Fail 6(3):387. doi: 10.1161/CIRCHEARTFAILURE.112.000118CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Lichtman JH, Bigger JT Jr., Blumenthal JA et al (2008) Depression and coronary heart disease: recommendations for screening, referral, and treatment: A science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation 118(17):1768–1775. doi: 10.1161/CIRCULATIONAHA.108.190769CrossRefPubMed Lichtman JH, Bigger JT Jr., Blumenthal JA et al (2008) Depression and coronary heart disease: recommendations for screening, referral, and treatment: A science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation 118(17):1768–1775. doi: 10.1161/CIRCULATIONAHA.108.190769CrossRefPubMed
8.
Zurück zum Zitat Woltz PC, Chapa DW, Friedmann E et al (2012) Effects of interventions on depression in heart failure: A systematic review. Heart Lung 41(5):469–483. doi: 10.1016/j.hrtlng.2012.06.002CrossRefPubMed Woltz PC, Chapa DW, Friedmann E et al (2012) Effects of interventions on depression in heart failure: A systematic review. Heart Lung 41(5):469–483. doi: 10.1016/j.hrtlng.2012.06.002CrossRefPubMed
9.
Zurück zum Zitat Freedland KE, Carney RM, Rich MW et al (2015) Cognitive behavior therapy for depression and self-care in heart failure patients: A randomized clinical trial. JAMA Intern Med 175(11):1773–1782. doi: 10.1001/jamainternmed.2015.5220CrossRefPubMedPubMedCentral Freedland KE, Carney RM, Rich MW et al (2015) Cognitive behavior therapy for depression and self-care in heart failure patients: A randomized clinical trial. JAMA Intern Med 175(11):1773–1782. doi: 10.1001/jamainternmed.2015.5220CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Blumenthal JA, Babyak MA, O’Connor C et al (2012) Effects of exercise training on depressive symptoms in patients with chronic heart failure: The HF-ACTION randomized trial. JAMA 308(5):465–474. doi: 10.1001/jama.2012.8720CrossRefPubMedPubMedCentral Blumenthal JA, Babyak MA, O’Connor C et al (2012) Effects of exercise training on depressive symptoms in patients with chronic heart failure: The HF-ACTION randomized trial. JAMA 308(5):465–474. doi: 10.1001/jama.2012.8720CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat World Health Organization (1992) ICD-10 Classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines. World Health Organization, Geneva World Health Organization (1992) ICD-10 Classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines. World Health Organization, Geneva
12.
Zurück zum Zitat American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5). American Psychiatric Publishing, Arlington VA American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, fifth edition (DSM-5). American Psychiatric Publishing, Arlington VA
13.
Zurück zum Zitat Lowe B, Kroenke K, Grafe K (2005) Detecting and monitoring depression with a two-item questionnaire (PHQ-2). J Psychosom Res 58(2):163–171. doi: 10.1016/j.jpsychores.2004.09.006CrossRefPubMed Lowe B, Kroenke K, Grafe K (2005) Detecting and monitoring depression with a two-item questionnaire (PHQ-2). J Psychosom Res 58(2):163–171. doi: 10.1016/j.jpsychores.2004.09.006CrossRefPubMed
14.
Zurück zum Zitat Piepenburg SM, Faller H, Gelbrich G et al (2015) Comparative potential of the 2 item versus the 9 item patient health questionnaire to predict death or rehospitalization in heart failure. Circ Heart Fail 8(3):464–472. doi: 10.1161/CIRCHEARTFAILURE.114.001488CrossRefPubMed Piepenburg SM, Faller H, Gelbrich G et al (2015) Comparative potential of the 2 item versus the 9 item patient health questionnaire to predict death or rehospitalization in heart failure. Circ Heart Fail 8(3):464–472. doi: 10.1161/CIRCHEARTFAILURE.114.001488CrossRefPubMed
15.
Zurück zum Zitat American Heart Association (2005) Heart disease and stroke statistics — 2005 update. American Heart Association, Dallas American Heart Association (2005) Heart disease and stroke statistics — 2005 update. American Heart Association, Dallas
17.
Zurück zum Zitat Vos T, Flaxman AD, Naghavi M et al (2012) Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 380(9859):2163–2196. doi: 10.1016/S0140-6736(12)61729-2CrossRefPubMed Vos T, Flaxman AD, Naghavi M et al (2012) Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 380(9859):2163–2196. doi: 10.1016/S0140-6736(12)61729-2CrossRefPubMed
18.
Zurück zum Zitat Busch MA, Maske UE, Ryl L et al (2013) Prevalence of depressive symptoms and diagnosed depression among adults in Germany: Results of the German Health Interview and Examination Survey for Adults (DEGS1). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(5–6):733–739. doi: 10.1007/s00103-013-1688-3CrossRefPubMed Busch MA, Maske UE, Ryl L et al (2013) Prevalence of depressive symptoms and diagnosed depression among adults in Germany: Results of the German Health Interview and Examination Survey for Adults (DEGS1). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(5–6):733–739. doi: 10.1007/s00103-013-1688-3CrossRefPubMed
19.
Zurück zum Zitat Vaccarino V, Kasl SV, Abramson J (2001) Depressive symptoms and risk of functional decline and death in patients with heart failure. J Am Coll Cardiol 38(1):199–205 CrossRefPubMedCrossRefPubMed Vaccarino V, Kasl SV, Abramson J (2001) Depressive symptoms and risk of functional decline and death in patients with heart failure. J Am Coll Cardiol 38(1):199–205 CrossRefPubMedCrossRefPubMed
20.
Zurück zum Zitat Faller H, Stork S, Schowalter M et al (2007) Is health-related quality of life an independent predictor of survival in patients with chronic heart failure? J Psychosom Res 63(5):533–538. doi: 10.1016/j.jpsychores.2007.06.026CrossRefPubMedCrossRefPubMed Faller H, Stork S, Schowalter M et al (2007) Is health-related quality of life an independent predictor of survival in patients with chronic heart failure? J Psychosom Res 63(5):533–538. doi: 10.1016/j.jpsychores.2007.06.026CrossRefPubMedCrossRefPubMed
21.
Zurück zum Zitat Klempfner R, Koifman E, Goldenberg I et al (2014) The Israel Nationwide Heart Failure Survey: Sex differences in early and late mortality for hospitalized heart failure patients. J Card Fail 20(3):193–198. doi: 10.1016/j.cardfail.2013.12.016CrossRefPubMedCrossRefPubMed Klempfner R, Koifman E, Goldenberg I et al (2014) The Israel Nationwide Heart Failure Survey: Sex differences in early and late mortality for hospitalized heart failure patients. J Card Fail 20(3):193–198. doi: 10.1016/j.cardfail.2013.12.016CrossRefPubMedCrossRefPubMed
22.
Zurück zum Zitat Brandsaeter B, Atar D, Agewall S et al (2011) Gender differences among Norwegian patients with heart failure. Int J Cardiol 146(3):354–358. doi: 10.1016/j.ijcard.2009.07.014CrossRefPubMed Brandsaeter B, Atar D, Agewall S et al (2011) Gender differences among Norwegian patients with heart failure. Int J Cardiol 146(3):354–358. doi: 10.1016/j.ijcard.2009.07.014CrossRefPubMed
23.
Zurück zum Zitat Lossnitzer N, Herzog W, Stork S et al (2012) Incidence rates and predictors of major and minor depression in patients with heart failure. Int J Cardiol 167(2):502–507. doi: 10.1016/j.ijcard.2012.01.062CrossRefPubMed Lossnitzer N, Herzog W, Stork S et al (2012) Incidence rates and predictors of major and minor depression in patients with heart failure. Int J Cardiol 167(2):502–507. doi: 10.1016/j.ijcard.2012.01.062CrossRefPubMed
24.
Zurück zum Zitat Havranek EP, Spertus JA, Masoudi FA et al (2004) Predictors of the onset of depressive symptoms in patients with heart failure. J Am Coll Cardiol 44(12):2333–2338. doi: 10.1016/j.jacc.2004.09.034CrossRefPubMed Havranek EP, Spertus JA, Masoudi FA et al (2004) Predictors of the onset of depressive symptoms in patients with heart failure. J Am Coll Cardiol 44(12):2333–2338. doi: 10.1016/j.jacc.2004.09.034CrossRefPubMed
25.
Zurück zum Zitat Luijendijk HJ, Tiemeier H, van den Berg JF et al (2010) Heart failure and incident late-life depression. J Am Geriatr Soc 58(8):1441–1448. doi: 10.1111/j.1532-5415.2010.02921.xCrossRefPubMed Luijendijk HJ, Tiemeier H, van den Berg JF et al (2010) Heart failure and incident late-life depression. J Am Geriatr Soc 58(8):1441–1448. doi: 10.1111/j.1532-5415.2010.02921.xCrossRefPubMed
26.
Zurück zum Zitat Hare DL, Toukhsati SR, Johansson P (2014) Depression and cardiovascular disease: A clinical review. Eur Heart J 35(21):1365–1372. doi: 10.1093/eurheartj/eht462CrossRefPubMed Hare DL, Toukhsati SR, Johansson P (2014) Depression and cardiovascular disease: A clinical review. Eur Heart J 35(21):1365–1372. doi: 10.1093/eurheartj/eht462CrossRefPubMed
27.
Zurück zum Zitat Carney RM, Freedland KE, Veith RC (2005) Depression, the autonomic nervous system, and coronary heart disease. Psychosom Med 67(Suppl):S29–S33. doi: 10.1097/01.psy.0000162254.61556.d5CrossRefPubMed Carney RM, Freedland KE, Veith RC (2005) Depression, the autonomic nervous system, and coronary heart disease. Psychosom Med 67(Suppl):S29–S33. doi: 10.1097/01.psy.0000162254.61556.d5CrossRefPubMed
28.
Zurück zum Zitat Rozanski A, Blumenthal JA, Davidson KW et al (2005) The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: The emerging field of behavioral cardiology. J Am Coll Cardiol 45(5):637–651. doi: 10.1016/j.jacc.2004.12.005CrossRefPubMed Rozanski A, Blumenthal JA, Davidson KW et al (2005) The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: The emerging field of behavioral cardiology. J Am Coll Cardiol 45(5):637–651. doi: 10.1016/j.jacc.2004.12.005CrossRefPubMed
29.
Zurück zum Zitat Kliks BR, Burgess MJ, Abildskov JA (1975) Influence of sympathetic tone on ventricular fibrillation threshold during experimental coronary occlusion. Am J Cardiol 36(1):45–49CrossRefPubMed Kliks BR, Burgess MJ, Abildskov JA (1975) Influence of sympathetic tone on ventricular fibrillation threshold during experimental coronary occlusion. Am J Cardiol 36(1):45–49CrossRefPubMed
30.
Zurück zum Zitat Schwartz PJ (1998) The autonomic nervous system and sudden death. Eur Heart J 19(Suppl F):F72–F80PubMed Schwartz PJ (1998) The autonomic nervous system and sudden death. Eur Heart J 19(Suppl F):F72–F80PubMed
31.
Zurück zum Zitat Yamaji M, Tsutamoto T, Kawahara C et al (2009) Serum cortisol as a useful predictor of cardiac events in patients with chronic heart failure: The impact of oxidative stress. Circ Heart Fail 2(6):608–615. doi: 10.1161/CIRCHEARTFAILURE.109.868513CrossRefPubMed Yamaji M, Tsutamoto T, Kawahara C et al (2009) Serum cortisol as a useful predictor of cardiac events in patients with chronic heart failure: The impact of oxidative stress. Circ Heart Fail 2(6):608–615. doi: 10.1161/CIRCHEARTFAILURE.109.868513CrossRefPubMed
32.
Zurück zum Zitat Wulsin LR, Singal BM (2003) Do depressive symptoms increase the risk for the onset of coronary disease? A systematic quantitative review. Psychosom Med 65(2):201–210CrossRefPubMed Wulsin LR, Singal BM (2003) Do depressive symptoms increase the risk for the onset of coronary disease? A systematic quantitative review. Psychosom Med 65(2):201–210CrossRefPubMed
33.
Zurück zum Zitat Fan H, Yu W, Zhang Q et al (2014) Depression after heart failure and risk of cardiovascular and all-cause mortality: A meta-analysis. Prev Med 63:36–42. doi: 10.1016/j.ypmed.2014.03.007CrossRefPubMed Fan H, Yu W, Zhang Q et al (2014) Depression after heart failure and risk of cardiovascular and all-cause mortality: A meta-analysis. Prev Med 63:36–42. doi: 10.1016/j.ypmed.2014.03.007CrossRefPubMed
34.
Zurück zum Zitat Song EK, Moser DK, Kang SM (2015) Association of depressive symptoms and micronutrient deficiency with cardiac event-free survival in patients with heart failure. J Card Fail 21(12):945–951. doi: 10.1016/j.cardfail.2015.10.007CrossRefPubMed Song EK, Moser DK, Kang SM (2015) Association of depressive symptoms and micronutrient deficiency with cardiac event-free survival in patients with heart failure. J Card Fail 21(12):945–951. doi: 10.1016/j.cardfail.2015.10.007CrossRefPubMed
35.
Zurück zum Zitat Ponikowski P, Voors AA, Anker SD et al (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 18(8):891–975. doi: 10.1002/ejhf.592CrossRefPubMed Ponikowski P, Voors AA, Anker SD et al (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail 18(8):891–975. doi: 10.1002/ejhf.592CrossRefPubMed
36.
Zurück zum Zitat Jiang W, Alexander J, Christopher E et al (2001) Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med 161(15):1849–1856CrossRefPubMed Jiang W, Alexander J, Christopher E et al (2001) Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med 161(15):1849–1856CrossRefPubMed
37.
Zurück zum Zitat Freedland KE, Carney RM, Rich MW et al (2016) Depression and multiple Rehospitalizations in patients with heart failure. Clin Cardiol 39(5):257–262. doi: 10.1002/clc.22520CrossRefPubMed Freedland KE, Carney RM, Rich MW et al (2016) Depression and multiple Rehospitalizations in patients with heart failure. Clin Cardiol 39(5):257–262. doi: 10.1002/clc.22520CrossRefPubMed
38.
Zurück zum Zitat Frasure-Smith N, Lesperance F, Habra M et al (2009) Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation 120(2):134–140 (133p following 140) doi: 10.1161/CIRCULATIONAHA.109.851675CrossRefPubMed Frasure-Smith N, Lesperance F, Habra M et al (2009) Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation 120(2):134–140 (133p following 140) doi: 10.1161/CIRCULATIONAHA.109.851675CrossRefPubMed
39.
Zurück zum Zitat Freedland KE, Hesseler MJ, Carney RM et al (2016) Major depression and long-term survival of patients with heart failure. Psychosom Med:1. doi: 10.1097/PSY.0000000000000346 Freedland KE, Hesseler MJ, Carney RM et al (2016) Major depression and long-term survival of patients with heart failure. Psychosom Med:1. doi: 10.1097/PSY.0000000000000346
40.
Zurück zum Zitat Beach SR, Januzzi JL, Mastromauro CA et al (2013) Patient health questionnaire-9 score and adverse cardiac outcomes in patients hospitalized for acute cardiac disease. J Psychosom Res 75(5):409–413. doi: 10.1016/j.jpsychores.2013.08.001CrossRefPubMed Beach SR, Januzzi JL, Mastromauro CA et al (2013) Patient health questionnaire-9 score and adverse cardiac outcomes in patients hospitalized for acute cardiac disease. J Psychosom Res 75(5):409–413. doi: 10.1016/j.jpsychores.2013.08.001CrossRefPubMed
41.
Zurück zum Zitat Jiang W, Krishnan R, Kuchibhatla M et al (2011) Characteristics of depression remission and its relation with cardiovascular outcome among patients with chronic heart failure (from the SADHART-CHF Study). Am J Cardiol 107(4):545–551. doi: 10.1016/j.amjcard.2010.10.013CrossRefPubMedPubMedCentral Jiang W, Krishnan R, Kuchibhatla M et al (2011) Characteristics of depression remission and its relation with cardiovascular outcome among patients with chronic heart failure (from the SADHART-CHF Study). Am J Cardiol 107(4):545–551. doi: 10.1016/j.amjcard.2010.10.013CrossRefPubMedPubMedCentral
42.
Zurück zum Zitat Cohen HW, Gibson G, Alderman MH (2000) Excess risk of myocardial infarction in patients treated with antidepressant medications: Association with use of tricyclic agents. Am J Med 108(1):2–8CrossRefPubMed Cohen HW, Gibson G, Alderman MH (2000) Excess risk of myocardial infarction in patients treated with antidepressant medications: Association with use of tricyclic agents. Am J Med 108(1):2–8CrossRefPubMed
43.
Zurück zum Zitat Wallenborn J, Angermann CE (2014) Herzinsuffizienz und Depression — Eine Wechselbeziehung mit vielfältigen Facetten. Klinikarzt 43(11):524–528CrossRef Wallenborn J, Angermann CE (2014) Herzinsuffizienz und Depression — Eine Wechselbeziehung mit vielfältigen Facetten. Klinikarzt 43(11):524–528CrossRef
44.
Zurück zum Zitat Piepenburg SM, Ertl G, Angermann CE (2016) Depression und Herzinsuffizienz — eine gefährliche Kombination. Dtsch Med Wochenschr 141(17):1222–1227CrossRefPubMed Piepenburg SM, Ertl G, Angermann CE (2016) Depression und Herzinsuffizienz — eine gefährliche Kombination. Dtsch Med Wochenschr 141(17):1222–1227CrossRefPubMed
45.
Zurück zum Zitat O’Connor CM, Jiang W, Kuchibhatla M et al (2010) Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. J Am Coll Cardiol 56(9):692–699. doi: 10.1016/j.jacc.2010.03.068CrossRefPubMedPubMedCentral O’Connor CM, Jiang W, Kuchibhatla M et al (2010) Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. J Am Coll Cardiol 56(9):692–699. doi: 10.1016/j.jacc.2010.03.068CrossRefPubMedPubMedCentral
46.
Zurück zum Zitat Angermann CE, Gelbrich G, Stork S et al (2016) Effect of Escitalopram on all-cause mortality and hospitalization in patients with heart failure and depression: the MOOD-HF randomized clinical trial. JAMA 315(24):2683–2693. doi: 10.1001/jama.2016.7635CrossRefPubMed Angermann CE, Gelbrich G, Stork S et al (2016) Effect of Escitalopram on all-cause mortality and hospitalization in patients with heart failure and depression: the MOOD-HF randomized clinical trial. JAMA 315(24):2683–2693. doi: 10.1001/jama.2016.7635CrossRefPubMed
47.
Zurück zum Zitat Gary RA, Dunbar SB, Higgins MK et al (2010) Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure. J Psychosom Res 69(2):119–131. doi: 10.1016/j.jpsychores.2010.01.013CrossRefPubMedPubMedCentral Gary RA, Dunbar SB, Higgins MK et al (2010) Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure. J Psychosom Res 69(2):119–131. doi: 10.1016/j.jpsychores.2010.01.013CrossRefPubMedPubMedCentral
48.
Zurück zum Zitat Huffman JC, Mastromauro CA, Beach SR et al (2014) Collaborative care for depression and anxiety disorders in patients with recent cardiac events: The Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med 174(6):927–935. doi: 10.1001/jamainternmed.2014.739CrossRefPubMed Huffman JC, Mastromauro CA, Beach SR et al (2014) Collaborative care for depression and anxiety disorders in patients with recent cardiac events: The Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med 174(6):927–935. doi: 10.1001/jamainternmed.2014.739CrossRefPubMed
49.
Zurück zum Zitat Piepoli MF, Conraads V, Corra U et al (2011) Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 13(4):347–357. doi: 10.1093/eurjhf/hfr017CrossRefPubMed Piepoli MF, Conraads V, Corra U et al (2011) Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail 13(4):347–357. doi: 10.1093/eurjhf/hfr017CrossRefPubMed
50.
Zurück zum Zitat McAlister FA, Lawson FM, Teo KK (2001) A systematic review of randomized trials of disease management programs in heart failure. Am J Med 110(5):378–384CrossRefPubMed McAlister FA, Lawson FM, Teo KK (2001) A systematic review of randomized trials of disease management programs in heart failure. Am J Med 110(5):378–384CrossRefPubMed
51.
Zurück zum Zitat Angermann CE, Stork S, Gelbrich G et al (2012) Mode of action and effects of standardized collaborative disease management on mortality and morbidity in patients with systolic heart failure: The Interdisciplinary Network for Heart Failure (INH) study. Circ Heart Fail 5(1):25–35. doi: 10.1161/CIRCHEARTFAILURE.111.962969CrossRefPubMed Angermann CE, Stork S, Gelbrich G et al (2012) Mode of action and effects of standardized collaborative disease management on mortality and morbidity in patients with systolic heart failure: The Interdisciplinary Network for Heart Failure (INH) study. Circ Heart Fail 5(1):25–35. doi: 10.1161/CIRCHEARTFAILURE.111.962969CrossRefPubMed
52.
Zurück zum Zitat Koehler F, Winkler S, Schieber M et al (2012) Telemedicine in heart failure: Pre-specified and exploratory subgroup analyses from the TIM-HF trial. Int J Cardiol 161(3):143–150. doi: 10.1016/j.ijcard.2011.09.007CrossRefPubMed Koehler F, Winkler S, Schieber M et al (2012) Telemedicine in heart failure: Pre-specified and exploratory subgroup analyses from the TIM-HF trial. Int J Cardiol 161(3):143–150. doi: 10.1016/j.ijcard.2011.09.007CrossRefPubMed
53.
Zurück zum Zitat Gunold H, Angermann CE (2015) Kognitive Dysfunktion, Depression und Angst bei Herzinsuffizienz. Aktuel Kardol 2015(4):379–386 Gunold H, Angermann CE (2015) Kognitive Dysfunktion, Depression und Angst bei Herzinsuffizienz. Aktuel Kardol 2015(4):379–386
54.
Zurück zum Zitat Glassman AH et al (2002) Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA 288:701–709CrossRefPubMed Glassman AH et al (2002) Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA 288:701–709CrossRefPubMed
55.
Zurück zum Zitat Berkman LF et al (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA 289:3106–3116CrossRefPubMed Berkman LF et al (2003) Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA 289:3106–3116CrossRefPubMed
56.
Zurück zum Zitat Lespérance F et al (2007) Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA 297:367–379CrossRefPubMed Lespérance F et al (2007) Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: The Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA 297:367–379CrossRefPubMed
57.
Zurück zum Zitat Van den Brink RH et al (2002) Treatment of depression after myocardial infarction and the effects on cardiac prognosis and quality of life: Rationale and outline of the Myocardial Infarction and Depression-Intervention Trial (MIND-IT). Am Heart J 144:219–225CrossRefPubMed Van den Brink RH et al (2002) Treatment of depression after myocardial infarction and the effects on cardiac prognosis and quality of life: Rationale and outline of the Myocardial Infarction and Depression-Intervention Trial (MIND-IT). Am Heart J 144:219–225CrossRefPubMed
Metadaten
Titel
Depression und Herzinsuffizienz — doppeltes Risiko?
Diagnostik, prognostische Bedeutung und Therapie einer unterschätzten Komorbidität
verfasst von
Dr. med. J. Wallenborn
Prof. Dr.med. C. E. Angermann
Publikationsdatum
08.02.2017
Verlag
Springer Medizin
Erschienen in
CME / Ausgabe 1-2/2017
Print ISSN: 1614-371X
Elektronische ISSN: 1614-3744
DOI
https://doi.org/10.1007/s11298-017-5973-6

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