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Erschienen in: Current Cardiology Reports 8/2023

08.07.2023 | Diversity and Health Equity in Cardiology (AE Johnson, Section Editor)

Incidence and Prevalence of Atrial Fibrillation in Latinos: What’s New Since the Study in Latinos (SOL)?

verfasst von: Apurva Khedagi, Francis Ugowe, Larry R. Jackson

Erschienen in: Current Cardiology Reports | Ausgabe 8/2023

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Abstract

Purpose of Review

To assess contemporary epidemiological trends in AF incidence and prevalence in the LatinX population after the Hispanic Community Health Study/Study of Latinos.

Recent Findings

Atrial fibrillation (AF) remains the most abnormal heart rhythm condition globally and disproportionately impacts morbidity and mortality of communities that have been historically disadvantaged. The incidence and prevalence of AF is lower in the LatinX population compared to White individuals despite a higher burden of classic risk factors associated with AF. Since the Hispanic Community Health Study/Study of Latinos study on AF, recent data continues to demonstrate a similar lower burden of AF in the LatinX population compared to White individuals. However, the rates of incident AF may be accelerating faster in the LatinX population compared to their White counterparts. Furthermore, studies have found environmental and genetic risk factors that are associated with the development of AF within LatinX individuals, which may help explain the rising development of AF among the LatinX community. Recent research continues to show that LatinX populations are less likely to be treated with stroke reduction and rhythm control strategies and have a disproportionately higher burden of poor outcomes associated with AF compared to White patients.

Summary

Our review illuminates that further inclusion of LatinX individuals in AF randomized control trials and observational studies is imperative to understand the incidence and prevalence of AF in the LatinX community and improve overall morbidity and mortality.
Literatur
1.
Zurück zum Zitat Schnabel RB et al. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. The Lancet. 2015;386(9989):154–62.CrossRef Schnabel RB et al. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. The Lancet. 2015;386(9989):154–62.CrossRef
2.
Zurück zum Zitat Go AS et al. Prevalence of diagnosed atrial fibrillation in adults national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors In Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285(18):2370–5.CrossRefPubMed Go AS et al. Prevalence of diagnosed atrial fibrillation in adults national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors In Atrial Fibrillation (ATRIA) Study. JAMA. 2001;285(18):2370–5.CrossRefPubMed
3.
Zurück zum Zitat Heckbert SR et al. Differences by race/ethnicity in the prevalence of clinically detected and monitor-detected atrial fibrillation. Circ Arrhythm Electrophysiol. 2020;13(1):e007698. Heckbert SR et al. Differences by race/ethnicity in the prevalence of clinically detected and monitor-detected atrial fibrillation. Circ Arrhythm Electrophysiol. 2020;13(1):e007698.
4.
Zurück zum Zitat Rodriguez CJ et al. Atrial fibrillation incidence and risk factors in relation to race-ethnicity and the population attributable fraction of atrial fibrillation risk factors: the Multi-Ethnic Study of Atherosclerosis. Ann Epidemiol. 2015;25(2):71–6. Rodriguez CJ et al. Atrial fibrillation incidence and risk factors in relation to race-ethnicity and the population attributable fraction of atrial fibrillation risk factors: the Multi-Ethnic Study of Atherosclerosis. Ann Epidemiol. 2015;25(2):71–6.
5.
Zurück zum Zitat Borzecki AM et al. Racial differences in the prevalence of atrial fibrillation among males. J Natl Med Assoc. 2008;100(2):237–45.PubMed Borzecki AM et al. Racial differences in the prevalence of atrial fibrillation among males. J Natl Med Assoc. 2008;100(2):237–45.PubMed
6.
Zurück zum Zitat Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22(8):983–8.CrossRefPubMed Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22(8):983–8.CrossRefPubMed
9.
Zurück zum Zitat Linares JD et al. Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: the Hispanic Community Health Study/Study of Latinos. Heart Rhythm. 2019;16(5):686–93.CrossRefPubMedPubMedCentral Linares JD et al. Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos: the Hispanic Community Health Study/Study of Latinos. Heart Rhythm. 2019;16(5):686–93.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat •• Alonso A et al. Epidemiology of atrial fibrillation in the All of Us Research Program. PLOS ONE. 2022;17(3):e0265498. This prospective cohort study found that in Hispanic participants recruited for the All of Us Research Program from 2017 to 2019, the prevalence of atrial fibrillation (AF) was 1.8% and the incidence of newly diagnosed AF was less than 5.9%. The findings of this study also noted that the rate of incident AF was higher in Hispanic participants compared to non-Hispanic White participants. •• Alonso A et al. Epidemiology of atrial fibrillation in the All of Us Research Program. PLOS ONE. 2022;17(3):e0265498. This prospective cohort study found that in Hispanic participants recruited for the All of Us Research Program from 2017 to 2019, the prevalence of atrial fibrillation (AF) was 1.8% and the incidence of newly diagnosed AF was less than 5.9%. The findings of this study also noted that the rate of incident AF was higher in Hispanic participants compared to non-Hispanic White participants.
11.
Zurück zum Zitat Dewland TA et al. Incident atrial fibrillation among Asians Hispanics Blacks and Whites. Circulation. 2013;128(23):2470–7.CrossRefPubMed Dewland TA et al. Incident atrial fibrillation among Asians Hispanics Blacks and Whites. Circulation. 2013;128(23):2470–7.CrossRefPubMed
12.
Zurück zum Zitat Essien UR et al. Disparities in anticoagulant therapy initiation for incident atrial fibrillation by race/ethnicity among patients in the Veterans Health Administration system. JAMA Netw Open. 2021;4(7):e2114234.CrossRefPubMedPubMedCentral Essien UR et al. Disparities in anticoagulant therapy initiation for incident atrial fibrillation by race/ethnicity among patients in the Veterans Health Administration system. JAMA Netw Open. 2021;4(7):e2114234.CrossRefPubMedPubMedCentral
14.
15.
Zurück zum Zitat Lloyd-Jones DM et al. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation. 2004;110(9):1042–6.CrossRefPubMed Lloyd-Jones DM et al. Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation. 2004;110(9):1042–6.CrossRefPubMed
16.
Zurück zum Zitat Alonso A et al. Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J. 2009;158(1):111–7.CrossRefPubMedPubMedCentral Alonso A et al. Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J. 2009;158(1):111–7.CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Osman M et al. Racial differences in the prevalence of diagnosed atrial fibrillation among hospitalized patients. Mayo Clin Proc. 2021;96(9):2495–7.CrossRefPubMed Osman M et al. Racial differences in the prevalence of diagnosed atrial fibrillation among hospitalized patients. Mayo Clin Proc. 2021;96(9):2495–7.CrossRefPubMed
18.
Zurück zum Zitat Reinhardt SW et al. National trends in the burden of atrial fibrillation during hospital admissions for heart failure. J Am Heart Assoc. 2021;10(11):e019412.CrossRefPubMedPubMedCentral Reinhardt SW et al. National trends in the burden of atrial fibrillation during hospital admissions for heart failure. J Am Heart Assoc. 2021;10(11):e019412.CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Laslett DB et al. Racial differences in the incidence of atrial fibrillation after cryptogenic stroke. Heart Rhythm. 2021;18(6):847–52.CrossRefPubMed Laslett DB et al. Racial differences in the incidence of atrial fibrillation after cryptogenic stroke. Heart Rhythm. 2021;18(6):847–52.CrossRefPubMed
20.
Zurück zum Zitat Shulman E et al. Relative contribution of modifiable risk factors for incident atrial fibrillation in Hispanics, African Americans and non-Hispanic Whites. Int J Cardiol. 2019;275:89–94.CrossRefPubMed Shulman E et al. Relative contribution of modifiable risk factors for incident atrial fibrillation in Hispanics, African Americans and non-Hispanic Whites. Int J Cardiol. 2019;275:89–94.CrossRefPubMed
21.
Zurück zum Zitat Chalazan B et al. Association of rare genetic variants and early-onset atrial fibrillation in ethnic minority individuals. JAMA Cardiol. 2021;6(7):811–9.CrossRefPubMedPubMedCentral Chalazan B et al. Association of rare genetic variants and early-onset atrial fibrillation in ethnic minority individuals. JAMA Cardiol. 2021;6(7):811–9.CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Gonzalez-Cordero AF et al. Insight on the genetics of atrial fibrillation in Puerto Rican Hispanics. Stroke Res Treat. 2021;8819896.PubMedPubMedCentral Gonzalez-Cordero AF et al. Insight on the genetics of atrial fibrillation in Puerto Rican Hispanics. Stroke Res Treat. 2021;8819896.PubMedPubMedCentral
23.
Zurück zum Zitat • Essien UR et al. Association of race and ethnicity with oral anticoagulation and associated outcomes in patients with atrial fibrillation: findings from the Get With The Guidelines-Atrial Fibrillation Registry. JAMA Cardiol. 2022;7(12):1207–17. This retrospective cohort study using data from the Get With The Guidelines-Atrial Fibrillation registry found that patients hospitalized with AF who identified as Hispanic were the least likely to be prescribed an oral anticoagulant on discharge compared to patients of other racial and ethnic groups and Hispanic patients had a higher stroke risk than White patients.CrossRefPubMed • Essien UR et al. Association of race and ethnicity with oral anticoagulation and associated outcomes in patients with atrial fibrillation: findings from the Get With The Guidelines-Atrial Fibrillation Registry. JAMA Cardiol. 2022;7(12):1207–17. This retrospective cohort study using data from the Get With The Guidelines-Atrial Fibrillation registry found that patients hospitalized with AF who identified as Hispanic were the least likely to be prescribed an oral anticoagulant on discharge compared to patients of other racial and ethnic groups and Hispanic patients had a higher stroke risk than White patients.CrossRefPubMed
24.
Zurück zum Zitat Chen LY et al. CHA2DS2-VASc score and stroke prediction in atrial fibrillation in Whites, Blacks, and Hispanics. Stroke. 2019;50(1):28–33.CrossRefPubMed Chen LY et al. CHA2DS2-VASc score and stroke prediction in atrial fibrillation in Whites, Blacks, and Hispanics. Stroke. 2019;50(1):28–33.CrossRefPubMed
25.
Zurück zum Zitat Mentias A et al. Racial and sex disparities in anticoagulation after electrical cardioversion for atrial fibrillation and flutter. J Am Heart Assoc. 2021;10(17):e021674.CrossRefPubMedPubMedCentral Mentias A et al. Racial and sex disparities in anticoagulation after electrical cardioversion for atrial fibrillation and flutter. J Am Heart Assoc. 2021;10(17):e021674.CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Eberly LA et al. Racial/ethnic and socioeconomic disparities in management of incident paroxysmal atrial fibrillation. JAMA Netw Open. 2021;4(2):e210247.CrossRefPubMedPubMedCentral Eberly LA et al. Racial/ethnic and socioeconomic disparities in management of incident paroxysmal atrial fibrillation. JAMA Netw Open. 2021;4(2):e210247.CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Khan MZ et al. Representation of women, older patients, ethnic, and racial minorities in trials of atrial fibrillation. Pacing Clin Electrophysiol. 2021;44(3):423–31.CrossRefPubMedPubMedCentral Khan MZ et al. Representation of women, older patients, ethnic, and racial minorities in trials of atrial fibrillation. Pacing Clin Electrophysiol. 2021;44(3):423–31.CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat • Sarraju A, Maron DJ, Rodriguez F. Under-reporting and under-representation of racial/ethnic minorities in major atrial fibrillation clinical trials. JACC: Clin Electrophysiol. 2020;6(6):739–41. Findings of this study note that only six of the 34 global clinical trials that formed the 2019 American Heart Association/American College of Cardiology/Heart Rhythm Society guidelines for AF reported Hispanic participants and Hispanic participants made up only 5.6% of the total study population of the six clinical trials which reported Hispanic participants. • Sarraju A, Maron DJ, Rodriguez F. Under-reporting and under-representation of racial/ethnic minorities in major atrial fibrillation clinical trials. JACC: Clin Electrophysiol. 2020;6(6):739–41. Findings of this study note that only six of the 34 global clinical trials that formed the 2019 American Heart Association/American College of Cardiology/Heart Rhythm Society guidelines for AF reported Hispanic participants and Hispanic participants made up only 5.6% of the total study population of the six clinical trials which reported Hispanic participants.
29.
Zurück zum Zitat Nunes JC et al. Underrepresentation of ethnic and racial minorities in atrial fibrillation clinical trials. Circulation: Arrhythmia and Electrophysiology. 2021;14(12):e010452. Nunes JC et al. Underrepresentation of ethnic and racial minorities in atrial fibrillation clinical trials. Circulation: Arrhythmia and Electrophysiology. 2021;14(12):e010452.
31.
Zurück zum Zitat Hoyt H et al. Demographic profile of patients undergoing catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2011;22(9):994–8.CrossRefPubMed Hoyt H et al. Demographic profile of patients undergoing catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2011;22(9):994–8.CrossRefPubMed
32.
Zurück zum Zitat Bhave PD et al. Race- and sex-related differences in care for patients newly diagnosed with atrial fibrillation. Heart Rhythm. 2015;12(7):1406–12.CrossRefPubMedPubMedCentral Bhave PD et al. Race- and sex-related differences in care for patients newly diagnosed with atrial fibrillation. Heart Rhythm. 2015;12(7):1406–12.CrossRefPubMedPubMedCentral
33.
34.
Zurück zum Zitat Golwala H et al. Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry. Am Heart J. 2016;174:29–36.CrossRefPubMed Golwala H et al. Racial/ethnic differences in atrial fibrillation symptoms, treatment patterns, and outcomes: insights from Outcomes Registry for Better Informed Treatment for Atrial Fibrillation Registry. Am Heart J. 2016;174:29–36.CrossRefPubMed
35.
Zurück zum Zitat Kapoor A et al. Disparities in anticoagulation use by race and ethnicity in long-term care residents with atrial fibrillation. J Am Heart Assoc. 2021;10(23):e023428.CrossRefPubMedPubMedCentral Kapoor A et al. Disparities in anticoagulation use by race and ethnicity in long-term care residents with atrial fibrillation. J Am Heart Assoc. 2021;10(23):e023428.CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Essien UR et al. Race/ethnicity and sex-related differences in direct oral anticoagulant initiation in newly diagnosed atrial fibrillation: a retrospective study of Medicare data. J Natl Med Assoc. 2020;112(1):103–8.PubMed Essien UR et al. Race/ethnicity and sex-related differences in direct oral anticoagulant initiation in newly diagnosed atrial fibrillation: a retrospective study of Medicare data. J Natl Med Assoc. 2020;112(1):103–8.PubMed
37.
38.
Zurück zum Zitat Bush D et al. Atrial fibrillation among African Americans, Hispanics and Caucasians: clinical features and outcomes from the AFFIRM trial. J Natl Med Assoc. 2006;98(3):330–9.PubMedPubMedCentral Bush D et al. Atrial fibrillation among African Americans, Hispanics and Caucasians: clinical features and outcomes from the AFFIRM trial. J Natl Med Assoc. 2006;98(3):330–9.PubMedPubMedCentral
39.
Zurück zum Zitat Gomez SE et al. Racial, ethnic, and sex disparities in atrial fibrillation management: rate and rhythm control. J Interv Card Electrophysiol. 2022. Gomez SE et al. Racial, ethnic, and sex disparities in atrial fibrillation management: rate and rhythm control. J Interv Card Electrophysiol. 2022.
Metadaten
Titel
Incidence and Prevalence of Atrial Fibrillation in Latinos: What’s New Since the Study in Latinos (SOL)?
verfasst von
Apurva Khedagi
Francis Ugowe
Larry R. Jackson
Publikationsdatum
08.07.2023
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 8/2023
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-023-01910-w

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