Skip to main content

12.03.2024

Integrative Approaches to Managing Gut Health

verfasst von: Marvin M. Singh

Erschienen in: Current Gastroenterology Reports

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

To summarize key integrative approaches to managing common gastrointestinal conditions.

Recent Findings

Lifestyle interventions like diet, exercise, and stress reduction impact the gut microbiome and gastrointestinal symptoms. Evidence supports mind-body therapies, herbs, certain supplements, and other modalities as complimentary approaches, when appropriate, for common conditions like irritable bowel syndrome or gastroesophageal reflux disease.

Summary

An integrative approach optimizes both conventional treatments and incorporates lifestyle modifications, complimentary modalities, and the doctor-patient relationship.
Fußnoten
1
Heidelbaugh J et al. AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome with Constipation. Gastroenterology 2022;163:118–136.
 
Literatur
2.
Zurück zum Zitat McEwen BS. Integrative medicine: breaking down silos of knowledge and practice an epigenetic approach. Metabolism. 2017;69S:S21–9.CrossRefPubMed McEwen BS. Integrative medicine: breaking down silos of knowledge and practice an epigenetic approach. Metabolism. 2017;69S:S21–9.CrossRefPubMed
3.
Zurück zum Zitat Chow E, et al. A body-mind-Spirit Model in Health. Soc Work Health Care. 2008;34(3–4):261–82. Chow E, et al. A body-mind-Spirit Model in Health. Soc Work Health Care. 2008;34(3–4):261–82.
4.
Zurück zum Zitat Skirbekk H, Middelthon AL, Hjortdahl P, Finset A. Mandates of trust in the doctor-patient relationship. Qual Health Res. 2011;21(9):1182–90.CrossRefPubMed Skirbekk H, Middelthon AL, Hjortdahl P, Finset A. Mandates of trust in the doctor-patient relationship. Qual Health Res. 2011;21(9):1182–90.CrossRefPubMed
5.
Zurück zum Zitat Hills RD Jr., Pontefract BA, Mishcon HR, Black CA, Sutton SC, Theberge CR. Gut Microbiome: Profound Implications for Diet and Disease. Nutrients. 2019;11(7). Hills RD Jr., Pontefract BA, Mishcon HR, Black CA, Sutton SC, Theberge CR. Gut Microbiome: Profound Implications for Diet and Disease. Nutrients. 2019;11(7).
6.
Zurück zum Zitat Gilbert JA, Blaser MJ, Caporaso JG, Jansson JK, Lynch SV, Knight R. Current understanding of the human microbiome. Nat Med. 2018;24(4):392–400.CrossRefPubMedPubMedCentral Gilbert JA, Blaser MJ, Caporaso JG, Jansson JK, Lynch SV, Knight R. Current understanding of the human microbiome. Nat Med. 2018;24(4):392–400.CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat * Singh M. Lifestyle Medicine. In: Mullin G, Singh M, Parian A, Clarke J, ed. Integrative Gastroenterology. 2 ed: Oxford University Press; 2020:599–616. An important review of how lifestyle medicine impacts the gut microbiome and overall health and it’s role in managing gastrointestinal disease. * Singh M. Lifestyle Medicine. In: Mullin G, Singh M, Parian A, Clarke J, ed. Integrative Gastroenterology. 2 ed: Oxford University Press; 2020:599–616. An important review of how lifestyle medicine impacts the gut microbiome and overall health and it’s role in managing gastrointestinal disease.
8.
Zurück zum Zitat Baratta F, Pastori D, Polimeni L, et al. Adherence to Mediterranean Diet and non-alcoholic fatty liver disease: effect on insulin resistance. Am J Gastroenterol. 2017;112(12):1832–9. Important article reviewing the role of the Mediterranean diet in NAFLD, fatty liver disease, and insulin resistance. It underscores the importance of a healthy well-balance diet in the management of gut health.CrossRefPubMed Baratta F, Pastori D, Polimeni L, et al. Adherence to Mediterranean Diet and non-alcoholic fatty liver disease: effect on insulin resistance. Am J Gastroenterol. 2017;112(12):1832–9. Important article reviewing the role of the Mediterranean diet in NAFLD, fatty liver disease, and insulin resistance. It underscores the importance of a healthy well-balance diet in the management of gut health.CrossRefPubMed
9.
Zurück zum Zitat Kolodziejczyk A, Zheng D, Elinav E. Diet-Microbiota interactions and personalized nutrition. Nat Rev Microbiol. 2019;7:742–53.CrossRef Kolodziejczyk A, Zheng D, Elinav E. Diet-Microbiota interactions and personalized nutrition. Nat Rev Microbiol. 2019;7:742–53.CrossRef
10.
Zurück zum Zitat Rosenfeld CS. Gut dysbiosis in animals due to Environmental Chemical exposures. Front Cell Infect Microbiol. 2017;7:396. An important article that reviews how environmental chemicals can influence the gut microbiome which can lead to impacts on overall health. Rosenfeld CS. Gut dysbiosis in animals due to Environmental Chemical exposures. Front Cell Infect Microbiol. 2017;7:396. An important article that reviews how environmental chemicals can influence the gut microbiome which can lead to impacts on overall health.
11.
Zurück zum Zitat Singh M, Mullin G, Diet. Environmental Chemicals, and the Gut Microbiome. In: Cohen A, vom Saal F, ed. Integrative Environmental Medicine. Vol 1. 1 ed2017. Singh M, Mullin G, Diet. Environmental Chemicals, and the Gut Microbiome. In: Cohen A, vom Saal F, ed. Integrative Environmental Medicine. Vol 1. 1 ed2017.
12.
Zurück zum Zitat Viennois E, Merlin D, Gewirtz AT, Chassaing B. Dietary Emulsifier-Induced Low-Grade inflammation promotes Colon carcinogenesis. Cancer Res. 2017;77(1):27–40.CrossRefPubMed Viennois E, Merlin D, Gewirtz AT, Chassaing B. Dietary Emulsifier-Induced Low-Grade inflammation promotes Colon carcinogenesis. Cancer Res. 2017;77(1):27–40.CrossRefPubMed
13.
Zurück zum Zitat Monda V, Villano I, Messina A, et al. Exercise modifies the gut microbiota with positive Health effects. Oxid Med Cell Longev. 2017;2017:3831972.CrossRefPubMedPubMedCentral Monda V, Villano I, Messina A, et al. Exercise modifies the gut microbiota with positive Health effects. Oxid Med Cell Longev. 2017;2017:3831972.CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Alammar N, Mullin G. The irritable bowel syndrome. In: Mullin GSM, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 435–57. Alammar N, Mullin G. The irritable bowel syndrome. In: Mullin GSM, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 435–57.
15.
Zurück zum Zitat Choi JJ, Eum SY, Rampersaud E, Daunert S, Abreu MT, Toborek M. Exercise attenuates PCB-induced changes in the mouse gut microbiome. Environ Health Perspect. 2013;121(6):725–30.CrossRefPubMedPubMedCentral Choi JJ, Eum SY, Rampersaud E, Daunert S, Abreu MT, Toborek M. Exercise attenuates PCB-induced changes in the mouse gut microbiome. Environ Health Perspect. 2013;121(6):725–30.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Poroyko VA, Carreras A, Khalyfa A, et al. Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice. Sci Rep. 2016;6:35405.ADSCrossRefPubMedPubMedCentral Poroyko VA, Carreras A, Khalyfa A, et al. Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice. Sci Rep. 2016;6:35405.ADSCrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Erdman SE, Poutahidis T. Microbes and oxytocin: benefits for host physiology and behavior. Int Rev Neurobiol. 2016;131:91–126.CrossRefPubMed Erdman SE, Poutahidis T. Microbes and oxytocin: benefits for host physiology and behavior. Int Rev Neurobiol. 2016;131:91–126.CrossRefPubMed
18.
Zurück zum Zitat Pascoe MC, Thompson DR, Jenkins ZM, Ski CF. Mindfulness mediates the physiological markers of stress: systematic review and meta-analysis. J Psychiatr Res. 2017;95:156–78.CrossRefPubMed Pascoe MC, Thompson DR, Jenkins ZM, Ski CF. Mindfulness mediates the physiological markers of stress: systematic review and meta-analysis. J Psychiatr Res. 2017;95:156–78.CrossRefPubMed
19.
Zurück zum Zitat Neuendorf R, Harding A, Stello N, Hanes D, Wahbeh H. Depression and anxiety in patients with inflammatory bowel disease: a systematic review. J Psychosom Res. 2016;87:70–80.CrossRefPubMed Neuendorf R, Harding A, Stello N, Hanes D, Wahbeh H. Depression and anxiety in patients with inflammatory bowel disease: a systematic review. J Psychosom Res. 2016;87:70–80.CrossRefPubMed
20.
Zurück zum Zitat Schoenfeld P. Advances in IBS 2016: a review of current and Emerging Data. Gastroenterol Hepatol. 2016;12(8 Suppl 3):1–11. Schoenfeld P. Advances in IBS 2016: a review of current and Emerging Data. Gastroenterol Hepatol. 2016;12(8 Suppl 3):1–11.
21.
Zurück zum Zitat Ford AC, Quigley EM, Lacy BE, et al. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2014;109(9):1350–65.CrossRefPubMed Ford AC, Quigley EM, Lacy BE, et al. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2014;109(9):1350–65.CrossRefPubMed
22.
Zurück zum Zitat * D’Silva A, MacQueen G, Nasser Y, Taylor LM, Vallance JK, Raman M. Yoga as a Therapy for Irritable Bowel Syndrome. Dig Dis Sci. 2019. An important article which reviews the role of yoga (an integrative therapy) in the role of IBS. This underscores the importance and utility of non-medicinal therapies in the management of gut health. * D’Silva A, MacQueen G, Nasser Y, Taylor LM, Vallance JK, Raman M. Yoga as a Therapy for Irritable Bowel Syndrome. Dig Dis Sci. 2019. An important article which reviews the role of yoga (an integrative therapy) in the role of IBS. This underscores the importance and utility of non-medicinal therapies in the management of gut health.
23.
Zurück zum Zitat Taneja I, Deepak KK, Poojary G, Acharya IN, Pandey RM, Sharma MP. Yogic versus conventional treatment in diarrhea-predominant irritable bowel syndrome: a randomized control study. Appl Psychophysiol Biofeedback. 2004;29(1). Taneja I, Deepak KK, Poojary G, Acharya IN, Pandey RM, Sharma MP. Yogic versus conventional treatment in diarrhea-predominant irritable bowel syndrome: a randomized control study. Appl Psychophysiol Biofeedback. 2004;29(1).
24.
Zurück zum Zitat Zhao J, Lu J, Yin X, et al. Comparison of electroacupuncture and mild-warm moxibustion on brain-gut function in patients with constipation-predominant irritable bowel syndrome: a randomized controlled trial. Chin J Integr Med. 2018;24(5):328–35.CrossRefPubMed Zhao J, Lu J, Yin X, et al. Comparison of electroacupuncture and mild-warm moxibustion on brain-gut function in patients with constipation-predominant irritable bowel syndrome: a randomized controlled trial. Chin J Integr Med. 2018;24(5):328–35.CrossRefPubMed
25.
Zurück zum Zitat Amato A, Liotta R, Mule F. Effects of menthol on circular smooth muscle of human colon: analysis of the mechanism of action. Eur J Pharmacol. 2014;740:295–301.CrossRefPubMed Amato A, Liotta R, Mule F. Effects of menthol on circular smooth muscle of human colon: analysis of the mechanism of action. Eur J Pharmacol. 2014;740:295–301.CrossRefPubMed
26.
Zurück zum Zitat Patrick L. Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments. Altern Med Rev. 2011;16(2):116–33.PubMed Patrick L. Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments. Altern Med Rev. 2011;16(2):116–33.PubMed
27.
Zurück zum Zitat Sethi T. Constipation. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 411–34. Sethi T. Constipation. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 411–34.
28.
Zurück zum Zitat Ciampa B, Ramos E, Borum M, Doman D. The emerging therapeutic role of Medical Foods for Gastrointestinal disorders. Gastroenterol Hepatol. 2017;13(2):104–15. Ciampa B, Ramos E, Borum M, Doman D. The emerging therapeutic role of Medical Foods for Gastrointestinal disorders. Gastroenterol Hepatol. 2017;13(2):104–15.
29.
Zurück zum Zitat Mullin G, Swift M. The Inside Tract. Rodale; 2011. Mullin G, Swift M. The Inside Tract. Rodale; 2011.
30.
Zurück zum Zitat Arrouk R, Herdes RE, Karpinski AC, Hyman PE. Serum-derived bovine immunoglobulin for children with diarrhea-predominant irritable bowel syndrome. Pediatr Health Med Ther. 2018;9:129–33.CrossRef Arrouk R, Herdes RE, Karpinski AC, Hyman PE. Serum-derived bovine immunoglobulin for children with diarrhea-predominant irritable bowel syndrome. Pediatr Health Med Ther. 2018;9:129–33.CrossRef
31.
Zurück zum Zitat Valentin N, Camilleri M, Carlson P et al. Potential mechanisms of effects of serum-derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea-predominant irritable bowel syndrome. Physiol Rep. 2017;5(5). Valentin N, Camilleri M, Carlson P et al. Potential mechanisms of effects of serum-derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea-predominant irritable bowel syndrome. Physiol Rep. 2017;5(5).
32.
Zurück zum Zitat Doldo P, Cosco V, Garieri P, Ruggiero G, Mancina RM, Cosco C, Spagnuolo R. Beta-glucan, inositol, and digestive enzymes improve quality of life in patients with inflammatory bowel disease and irritable bowel syndrome. Eur Rev Med Pharmacol Sci. 2017;21(2 Supp):102–7.PubMed Doldo P, Cosco V, Garieri P, Ruggiero G, Mancina RM, Cosco C, Spagnuolo R. Beta-glucan, inositol, and digestive enzymes improve quality of life in patients with inflammatory bowel disease and irritable bowel syndrome. Eur Rev Med Pharmacol Sci. 2017;21(2 Supp):102–7.PubMed
33.
Zurück zum Zitat Verne GN, Salameh H, Basra S, et al. Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut. 2019;68(6):996–1002.CrossRefPubMed Verne GN, Salameh H, Basra S, et al. Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome. Gut. 2019;68(6):996–1002.CrossRefPubMed
34.
Zurück zum Zitat Siva S, Rubin DT, Gulotta G, Wroblewski K, Pekow J. Zinc Deficiency is Associated with Poor Clinical outcomes in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2017;23(1):152–7.CrossRefPubMed Siva S, Rubin DT, Gulotta G, Wroblewski K, Pekow J. Zinc Deficiency is Associated with Poor Clinical outcomes in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2017;23(1):152–7.CrossRefPubMed
35.
Zurück zum Zitat Lang A, Salomon N, Wu JC, et al. Curcumin in Combination with Mesalamine induces remission in patients with mild-to-moderate Ulcerative Colitis in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2015;13(8):1444–e14491441.CrossRefPubMed Lang A, Salomon N, Wu JC, et al. Curcumin in Combination with Mesalamine induces remission in patients with mild-to-moderate Ulcerative Colitis in a Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2015;13(8):1444–e14491441.CrossRefPubMed
36.
Zurück zum Zitat Langhorst J, Wulfert H, Lauche R, et al. Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases. J Crohns Colitis. 2015;9(1):86–106.CrossRefPubMed Langhorst J, Wulfert H, Lauche R, et al. Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases. J Crohns Colitis. 2015;9(1):86–106.CrossRefPubMed
37.
Zurück zum Zitat Hood MM, Jedel S. Mindfulness-based interventions in inflammatory bowel disease. Gastroenterol Clin North Am. 2017;46(4):859–74.CrossRefPubMed Hood MM, Jedel S. Mindfulness-based interventions in inflammatory bowel disease. Gastroenterol Clin North Am. 2017;46(4):859–74.CrossRefPubMed
38.
Zurück zum Zitat Abraham BP, Quigley EMM. Probiotics in Inflammatory Bowel Disease. Gastroenterol Clin North Am. 2017;46(4):769–82.CrossRefPubMed Abraham BP, Quigley EMM. Probiotics in Inflammatory Bowel Disease. Gastroenterol Clin North Am. 2017;46(4):769–82.CrossRefPubMed
39.
Zurück zum Zitat Gyawali CP, Kahrilas PJ, Savarino E, et al. Modern diagnosis of GERD: the Lyon Consensus. Gut. 2018;67(7):1351–62.CrossRefPubMed Gyawali CP, Kahrilas PJ, Savarino E, et al. Modern diagnosis of GERD: the Lyon Consensus. Gut. 2018;67(7):1351–62.CrossRefPubMed
40.
Zurück zum Zitat Slater R, Mathis SS, Sierpina V. Upper Gastrointestinal disorders: GERD, Dyspepsia, and peptic Ulcer Disease. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 363–90. Slater R, Mathis SS, Sierpina V. Upper Gastrointestinal disorders: GERD, Dyspepsia, and peptic Ulcer Disease. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. Volume 2. ed: Oxford University Press; 2020. pp. 363–90.
42.
Zurück zum Zitat Ghayur MN, Gilani AH. Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders. Dig Dis Sci. 2005;50(10):1889–97.CrossRefPubMed Ghayur MN, Gilani AH. Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders. Dig Dis Sci. 2005;50(10):1889–97.CrossRefPubMed
43.
Zurück zum Zitat Wu K, Rayner C, Chuah S, et al. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol. 2008;20(5):436–40.CrossRefPubMed Wu K, Rayner C, Chuah S, et al. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol. 2008;20(5):436–40.CrossRefPubMed
44.
Zurück zum Zitat Bang CS, Yang YJ, Baik GH. Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis. Med (Baltim). 2019;98(4):e14241.CrossRef Bang CS, Yang YJ, Baik GH. Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis. Med (Baltim). 2019;98(4):e14241.CrossRef
45.
Zurück zum Zitat Glasinovic E, Wynter E, Arguero J, et al. Treatment of supragastric belching with cognitive behavioral therapy improves qualit of life and reduces acid gastroesophageal reflux. Am J Gastroenterol. 2018;113(4):539–47.CrossRefPubMed Glasinovic E, Wynter E, Arguero J, et al. Treatment of supragastric belching with cognitive behavioral therapy improves qualit of life and reduces acid gastroesophageal reflux. Am J Gastroenterol. 2018;113(4):539–47.CrossRefPubMed
46.
Zurück zum Zitat Malfertheiner P. STW 5 (Iberogast) Therapy in Gastrointestinal Functional disorders. Dig Dis. 2017;35(Suppl 1):25–9.CrossRefPubMed Malfertheiner P. STW 5 (Iberogast) Therapy in Gastrointestinal Functional disorders. Dig Dis. 2017;35(Suppl 1):25–9.CrossRefPubMed
48.
Zurück zum Zitat Chedid V, Clarke J, Roland B, Dunbar K, Koh J, Justino E, Tomakin E, Mullin G. Herbal therapy is equivalent to Rifaximin for the treatment of small intestinal bacterial overgrowth. Glob Adv Health Med. 2014;3(3):16–24.CrossRefPubMedPubMedCentral Chedid V, Clarke J, Roland B, Dunbar K, Koh J, Justino E, Tomakin E, Mullin G. Herbal therapy is equivalent to Rifaximin for the treatment of small intestinal bacterial overgrowth. Glob Adv Health Med. 2014;3(3):16–24.CrossRefPubMedPubMedCentral
49.
Zurück zum Zitat Ankri S, Mirelman D. Antimicrobial properties of allicin from garlic. Microbes Infect. 1999;1(2):125–9.CrossRefPubMed Ankri S, Mirelman D. Antimicrobial properties of allicin from garlic. Microbes Infect. 1999;1(2):125–9.CrossRefPubMed
50.
Zurück zum Zitat Wah Kheong C, Nik Mustapha NR, Mahadeva S. A Randomized Trial of Silymarin for the Treatment of Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2017;15(12):1940–9. e1948.CrossRefPubMed Wah Kheong C, Nik Mustapha NR, Mahadeva S. A Randomized Trial of Silymarin for the Treatment of Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2017;15(12):1940–9. e1948.CrossRefPubMed
51.
Zurück zum Zitat Antunes C, Dadabhai A. Liver Disease. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. 2 ed. Oxford University Press; 2020. Antunes C, Dadabhai A. Liver Disease. In: Mullin G, Singh M, Parian A, Clarke J, editors. Integrative gastroenterology. 2 ed. Oxford University Press; 2020.
Metadaten
Titel
Integrative Approaches to Managing Gut Health
verfasst von
Marvin M. Singh
Publikationsdatum
12.03.2024
Verlag
Springer US
Erschienen in
Current Gastroenterology Reports
Print ISSN: 1522-8037
Elektronische ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-024-00927-7

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

Nach Herzinfarkt mit Typ-1-Diabetes schlechtere Karten als mit Typ 2?

29.05.2024 Herzinfarkt Nachrichten

Bei Menschen mit Typ-2-Diabetes sind die Chancen, einen Myokardinfarkt zu überleben, in den letzten 15 Jahren deutlich gestiegen – nicht jedoch bei Betroffenen mit Typ 1.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Costims – das nächste heiße Ding in der Krebstherapie?

28.05.2024 Onkologische Immuntherapie Nachrichten

„Kalte“ Tumoren werden heiß – CD28-kostimulatorische Antikörper sollen dies ermöglichen. Am besten könnten diese in Kombination mit BiTEs und Checkpointhemmern wirken. Erste klinische Studien laufen bereits.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.