Background
Methods
Study population
Histopathological examination
Clinical characteristics
Statistical analysis
Results
General situation
Clinical characteristics | Non-amnionitis group (186) | Amnionitis group (35) | P |
---|---|---|---|
Maternal age(y) | 30.62 ± 5.38 | 30.89 ± 6.80 | 0.797 |
Gestational age(d) | 34.14 ± 2.06 | 32.00 ± 2.71 | <0.001 |
Placental weight(g) | 480.71 ± 150.43 | 475.86 ± 106.68 | 0.856 |
Birth weight (kg) | 2.26 ± 0.58 | 1.93 ± 0.64 | 0.003 |
Antenatal glucocorticoids,n,(%) | 46(24.7%) | 12(34.3%) | 0.239 |
Premature rupture,n,(%) | 64(34.0%) | 16(45.7%) | 0.186 |
Cesarean section, n,(%) | 96(51.6%) | 16(45.7%) | 0.522 |
Male, n, (%) | 107(57.5%) | 16(45.7%) | 0.197 |
Apgar score 1 min ≤ 7, n, (%) | 7(3.8%) | 3(8.6%) | 0.417 |
Apgar score 5 min ≤ 7, n, (%) | 4(2.2%) | 1(2.9%) | 1.000 |
PLT,≤150 × 109/L, n, (%) | 12(6.5%) | 1(2.9%) | 0.662 |
Hospitalization(d) | 18.84 ± 16.80 | 25.71 ± 19.23 | 0.031 |
Neonatal outcome
IVH staging | Non-amnionitis group (186) | Amnionitis group (35) | P |
---|---|---|---|
IVH, n, (%) | 26(13.98%) | 13(37.14%) | 0.002 |
Early-onset, n, (%) | 14(7.53%) | 6(17.14%) | 0.069 |
Late-onset, n, (%) | 12(6.45%) | 7(20.00%) | 0.009 |
Outcomes | Non- amnionitis group (186) | Amnionitis group (35) | P | OR(95%CI) | *Adjusted P | *Adjusted OR(95%CI) |
---|---|---|---|---|---|---|
IVH,n, (%) | 26(13.98%) | 13(37.14%) | 0.002 | 3.636 (1.632–8.102) | 0.046 | 2.471 (1.015–6.015) |
BPD,n,(%) | 7(3.8%) | 3(8.6%) | 0.222 | 2.397 (0.589–9.759) | 0.444 | 0.493 (0.080–3.015) |
NEC,n, (%) | 20(10.8%) | 3(8.6%) | 0.699 | 0.778 (0.218–2.774) | 0.117 | 0.322 (0.078–1.331) |
ROP,n, (%) | 16(8.6%) | 2(5.7%) | 0.569 | 0.644 (0.141–2.934) | 0.104 | 0.251 (0.048–1.328) |
Sepsis, n, (%) | 1(0.5%) | 1(2.9%) | 0.235 | 5.441 (0.332–89.106) | 0.415 | 3.740 (0.157–89.228) |