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Journal of Pediatric Neuropsychology

Erschienen in:

01.12.2022

Sex Differences, Academic Outcomes, and the Impact of Cranial Radiation in Pediatric Medulloblastoma

verfasst von: Lia K. Thibodaux, Jesse Bledsoe, David Breiger

Erschienen in: Journal of Pediatric Neuropsychology | Ausgabe 4/2022

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Abstract

Introduction

Treatment for brain tumors in children has been associated with difficulties in neurocognitive functioning. The present study examined the differences in academic outcomes for male and female medulloblastoma survivors who were treated with and without cranial radiation.

Methods

Data from 39 medulloblastoma survivors were collected retrospectively. Patients included in the study were clinically referred for a neuropsychological evaluation. One-way ANOVAs were used to examine differences in academic outcomes for male and female patients as well as patients who received and did not receive radiation as part of their treatment.

Results

Analyses indicated significant differences across male and female medulloblastoma survivors for sight word reading, phonological decoding, and mathematical calculation. Significant differences were not observed for patients who did and did not receive cranial radiation.

Discussion

Similar to findings examining differences in intellectual outcomes for brain tumor survivors, males performed lower than females approximately 4 years post-treatment. This suggests that males may be particularly vulnerable to neurocognitive difficulties following treatment for medulloblastoma and earlier monitoring and assessment may be warranted. Sex differences in brain development may be related to academic outcomes for pediatric brain tumor patients. Additional research is needed in the area.

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Titel: Sex Differences, Academic Outcomes, and the Impact of Cranial Radiation in Pediatric Medulloblastoma
verfasst von: Lia K. Thibodaux
Jesse Bledsoe
David Breiger
Publikationsdatum: 01.12.2022
Verlag: Springer International Publishing
Erschienen in: Journal of Pediatric Neuropsychology / Ausgabe 4/2022
Print ISSN: 2199-2681
Elektronische ISSN: 2199-2673
DOI: https://doi.org/10.1007/s40817-022-00131-3

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