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Erschienen in: Clinical Neuroradiology 3/2023

03.04.2023 | Original Article

Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window

verfasst von: Piers Klein, Xiaochuan Huo, Yimin Chen, Mohamad Abdalkader, Zhongming Qiu, Simon Nagel, Jean Raymond, Liping Liu, James E. Siegler, Daniel Strbian, Thalia S. Field, Shadi Yaghi, Muhammad M. Qureshi, Jelle Demeestere, Volker Puetz, Anne Berberich, Patrik Michel, Urs Fischer, Johannes Kaesmacher, Hiroshi Yamagami, Fana Alemseged, Georgios Tsivgoulis, Wouter J. Schonewille, Wei Hu, Xinfeng Liu, Chuanhui Li, Xunming Ji, Brian Drumm, Soma Banerjee, Simona Sacco, Else C. Sandset, Espen Saxhaug Kristoffersen, Peter Slade, Robert Mikulik, Michele Romoli, Francesco Diana, Kailash Krishnan, Permesh Dhillon, Jin Soo Lee, Ekkehard Kasper, Hormuzdiyar Dasenbrock, Mai Duy Ton, Rytis Masiliūnas, Anita Ante Arsovska, João Pedro Marto, Adam A. Dmytriw, Robert W. Regenhardt, Gisele Sampaio Silva, Timo Siepmann, Dapeng Sun, Hongfei Sang, Jose Danilo Diestro, Pengfei Yang, Mahmoud H. Mohammaden, Fengli Li, Hesham E. Masoud, Alice Ma, Raynald, Aravind Ganesh, Jianmin Liu, Lukas Meyer, Diederik W. J. Dippel, Götz Thomalla, Mark Parsons, Adnan I. Qureshi, Mayank Goyal, Albert J. Yoo, Bertrand Lapergue, Osama O. Zaidat, Hui-Sheng Chen, Bruce C. V. Campbell, Tudor G. Jovin, Raul G. Nogueira, Zhongrong Miao, Gustavo Saposnik, Thanh N. Nguyen

Erschienen in: Clinical Neuroradiology | Ausgabe 3/2023

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Abstract

Background

The proper imaging modality for use in the selection of patients for endovascular thrombectomy (EVT) presenting in the late window remains controversial, despite current guidelines advocating the use of advanced imaging in this population. We sought to understand if clinicians with different specialty training differ in their approach to patient selection for EVT in the late time window.

Methods

We conducted an international survey of stroke and neurointerventional clinicians between January and May 2022 with questions focusing on imaging and treatment decisions of large vessel occlusion (LVO) patients presenting in the late window. Interventional neurologists, interventional neuroradiologists, and endovascular neurosurgeons were defined as interventionists whereas all other specialties were defined as non-interventionists. The non-interventionist group was defined by all other specialties of the respondents: stroke neurologist, neuroradiologist, emergency medicine physician, trainee (fellows and residents) and others.

Results

Of 3000 invited to participate, 1506 (1027 non-interventionists, 478 interventionists, 1 declined to specify) physicians completed the study. Interventionist respondents were more likely to proceed directly to EVT (39.5% vs. 19.5%; p < 0.0001) compared to non-interventionist respondents in patients with favorable ASPECTS (Alberta Stroke Program Early CT Score). Despite no difference in access to advanced imaging, interventionists were more likely to prefer CT/CTA alone (34.8% vs. 21.0%) and less likely to prefer CT/CTA/CTP (39.1% vs. 52.4%) for patient selection (p < 0.0001). When faced with uncertainty, non-interventionists were more likely to follow clinical guidelines (45.1% vs. 30.2%) while interventionists were more likely to follow their assessment of evidence (38.7% vs. 27.0%) (p < 0.0001).

Conclusion

Interventionists were less likely to use advanced imaging techniques in selecting LVO patients presenting in the late window and more likely to base their decisions on their assessment of evidence rather than published guidelines. These results reflect gaps between interventionists and non-interventionists reliance on clinical guidelines, the limits of available evidence, and clinician belief in the utility of advanced imaging.
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Metadaten
Titel
Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window
verfasst von
Piers Klein
Xiaochuan Huo
Yimin Chen
Mohamad Abdalkader
Zhongming Qiu
Simon Nagel
Jean Raymond
Liping Liu
James E. Siegler
Daniel Strbian
Thalia S. Field
Shadi Yaghi
Muhammad M. Qureshi
Jelle Demeestere
Volker Puetz
Anne Berberich
Patrik Michel
Urs Fischer
Johannes Kaesmacher
Hiroshi Yamagami
Fana Alemseged
Georgios Tsivgoulis
Wouter J. Schonewille
Wei Hu
Xinfeng Liu
Chuanhui Li
Xunming Ji
Brian Drumm
Soma Banerjee
Simona Sacco
Else C. Sandset
Espen Saxhaug Kristoffersen
Peter Slade
Robert Mikulik
Michele Romoli
Francesco Diana
Kailash Krishnan
Permesh Dhillon
Jin Soo Lee
Ekkehard Kasper
Hormuzdiyar Dasenbrock
Mai Duy Ton
Rytis Masiliūnas
Anita Ante Arsovska
João Pedro Marto
Adam A. Dmytriw
Robert W. Regenhardt
Gisele Sampaio Silva
Timo Siepmann
Dapeng Sun
Hongfei Sang
Jose Danilo Diestro
Pengfei Yang
Mahmoud H. Mohammaden
Fengli Li
Hesham E. Masoud
Alice Ma
Raynald
Aravind Ganesh
Jianmin Liu
Lukas Meyer
Diederik W. J. Dippel
Götz Thomalla
Mark Parsons
Adnan I. Qureshi
Mayank Goyal
Albert J. Yoo
Bertrand Lapergue
Osama O. Zaidat
Hui-Sheng Chen
Bruce C. V. Campbell
Tudor G. Jovin
Raul G. Nogueira
Zhongrong Miao
Gustavo Saposnik
Thanh N. Nguyen
Publikationsdatum
03.04.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Neuroradiology / Ausgabe 3/2023
Print ISSN: 1869-1439
Elektronische ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-023-01284-0

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