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European Archives of Oto-Rhino-Laryngology

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17.08.2023 | Rhinology

Systemic inflammation response index predicts the postoperative recurrence of chronic rhinosinusitis with nasal polyps: a retrospective study in the Chinese population

verfasst von: Yuqing Yang, Jing Zhu, Mengyu Zhang, Yihong Wang, Fuwei Cheng, Wenxia Ma, Manyi Li

Erschienen in: European Archives of Oto-Rhino-Laryngology | Ausgabe 1/2024

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Abstract

Purpose

Endoscopic sinus surgery (ESS) is now frequently used to treat chronic sinusitis with nasal polyps (CRSwNP), but postoperative recurrence plagues many patients. We aimed to assess the value of the systemic inflammation response index (SIRI) and the systemic immune-inflammatory index (SII) for the prediction of postoperative recurrence in patients with CRSwNP.

Methods

A total of 143 patients with CRSwNP and 76 age- and sex-matched healthy subjects were enrolled. Patients were divided into the recurrence group and the non-recurrence group according to the recurrence of CRSwNP. Univariate and multivariate analyses showed independent risk factors for the recurrence. A receiver operating characteristic curve analysis was conducted to assess the predictive accuracy of the variables and determine the optimal cut-off values. Finally, a survival analysis was conducted.

Results

Univariate analysis revealed that age, sex, CRP, EOS, SIRI, SII, NLR, ELR, and Lund–Mackay CT scores were significant predictors of the recurrence of CRSwNP. Multivariate analysis confirmed that SIRI (OR = 1.310, p < 0.001) and Lund–Mackay CT scores (OR = 1.396, p < 0.001) were independent predictors. SIRI (AUC = 0.761, 95% CI: 0.685–0.836) had a certain value in predicting the recurrence of CRSwNP.

Conclusion

SIRI is a potential predictive marker of the postoperative recurrence of CRSwNP.

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Titel: Systemic inflammation response index predicts the postoperative recurrence of chronic rhinosinusitis with nasal polyps: a retrospective study in the Chinese population
verfasst von: Yuqing Yang
Jing Zhu
Mengyu Zhang
Yihong Wang
Fuwei Cheng
Wenxia Ma
Manyi Li
Publikationsdatum: 17.08.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: European Archives of Oto-Rhino-Laryngology / Ausgabe 1/2024
Print ISSN: 0937-4477
Elektronische ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-023-08182-8

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Systemic inflammation response index predicts the postoperative recurrence of chronic rhinosinusitis with nasal polyps: a retrospective study in the Chinese population

Abstract

Purpose

Methods

Results

Conclusion

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Abstract

Purpose

Methods

Results

Conclusion

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