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27.04.2022 | Review Article

An evidence-based surgical algorithm for management of odontogenic keratocyst

verfasst von: Fadekemi Olufunmilayo Oginni, Nasser Alasseri, Oladunni Mojirayo Ogundana, Bamidele Adetokunbo Famurewa, Anthony Pogrel, Essam Ahmed Al-Moraissi

Erschienen in: Oral and Maxillofacial Surgery | Ausgabe 2/2023

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Abstract

The effective management of odontogenic keratocyst (OKC) remains a subject of interest and confusion in the oral and maxillofacial surgery literature. Currently, there is a lack of consensus regarding the most appropriate treatment for patients with OKC. Of the various treatment options available, no modality to date has been shown to demonstrate a zero or near-zero recurrence rates except wide resection with clear margins. With the prevailing dearth of evidence based surgical protocols for the management of patients with OKC in the literature, this study aims to present a surgical algorithm, based on meta-analysis results, that hopefully will be beneficial in enhancing treatment of patients with this condition. Also, new meta-analysis was done to compare between modified Carnoy’s solution (MCS) and 5-fluorouracil (5-FU) in respect of recurrence rate of OKC. Using parameters like size, lesion type (primary or secondary), syndromic or solitary nature of the lesion, presence of cortical perforations, and locularity; we present a decision tree, to aid treatment planning and help attain the least chance of recurrence in the management of the OKC. There was very low-quality evidence indicating that application of 5-FU, after enucleation and peripheral ostectomy of OKCs, significantly lowered recurrence rate when compared to MCS (RR = 0.087, CI: 0.017 to 0.436, P value = 0.003).

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Titel: An evidence-based surgical algorithm for management of odontogenic keratocyst
verfasst von: Fadekemi Olufunmilayo Oginni
Nasser Alasseri
Oladunni Mojirayo Ogundana
Bamidele Adetokunbo Famurewa
Anthony Pogrel
Essam Ahmed Al-Moraissi
Publikationsdatum: 27.04.2022
Verlag: Springer Berlin Heidelberg
Erschienen in: Oral and Maxillofacial Surgery / Ausgabe 2/2023
Print ISSN: 1865-1550
Elektronische ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-022-01064-z

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Weitere Artikel der Ausgabe 2/2023

Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: a micro‐computed tomography and positron emission tomography study in rabbits

Does implant placement using a minimally invasive technique increase early failures among trainees at an academic center?

Orbital reconstruction: a systematic review and meta-analysis evaluating the role of patient-specific implants

Evaluation of crestal sinus floor elevations using versah burs with simultaneous implant placement, at residual bone height ≥ 2.0 _ < 6.0 mm. A prospective clinical study

Surgical treatment of 61 consecutive patients with maxillary stage 3 medication–related osteonecrosis of the jaws using a pedicled buccal fat pad

Comparison of two surgical techniques (HOO vs. BSSO) for mandibular osteotomies in orthognathic surgery—a 10-year retrospective study

Update Chirurgie