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Erschienen in:
28.11.2022 | Male Sexual Dysfunction and Disorders (K Mishra, Section Editor)
Fungal Infections of Urologic Prostheses and Permanent Devices: a Systematic Review of Current Literature
Erschienen in: Current Sexual Health Reports | Ausgabe 1/2023
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Purpose of Review
There is a dearth of robust, peer-reviewed literature detailing the epidemiology, natural history, and sequelae associated with fungal infections of urologic implants, prostheses, and permanent devices. We curated and analyzed the available literature on this topic in concordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses system (PRISMA) criteria. The purpose of this systematic review is to consolidate the available research and highlight areas that require greater exploration.
Recent Findings
As hypothesized, the literature investigating fungal infections of urologic implants and prostheses is scant. There were, however, several studies detailing the mycobiome, clinical outcomes, and risk factors associated with fungal infections of indwelling urinary catheters. Of the 20 studies that met inclusion criteria, only 4 focused on prosthetic devices, 3 for inflatable penile prosthetics and 1 for the adjustable transobturator male system. There were 15 studies pertaining to chronic indwelling urinary catheters and 1 study about chronic nephrostomy tubes. Furthermore, there were no studies investigating fungal infections of common urologic implants such as slings, sacral neuromodulators, or artificial urinary sphincters.
Summary
This detailed systematic review found that the vast majority of studies focus on fungal infections associated with indwelling urinary catheters. There are virtually no retrospective or prospective studies investigating fungal infections of the various urologic implants and prostheses routinely used. Moreover, nearly half the studies included in this review were published over 20 years ago. There is a pressing need for more foundational literature on this topic that may ultimately yield sound prophylactic and management strategies.