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Erschienen in: Current Sexual Health Reports 1/2023

08.02.2023 | Male Sexual Dysfunction and Disorders (K Mishra, Section Editor)

Testosterone Therapy in Oncologic Patients

verfasst von: Emily Solsrud, Marne Louters, Amy Pearlman

Erschienen in: Current Sexual Health Reports | Ausgabe 1/2023

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Abstract

Purpose of Review

Testosterone deficiency (TD) disproportionately affects men with cancer due to several risk factors, including treatments and direct physiologic effects of the cancer disease process. Research and formal guidelines to aid physicians in diagnosing and treating TD in cancer patients are limited, causing this population to be grossly under-treated. There is an opportunity to safely treat these patients and positively impact several aspects of quality of life.

Recent Findings

While the treatment of TD has been well studied in non-oncologic patients, studies in cancer patients are limited and include retrospective, observational, pilot, and randomized-controlled trials.

Summary

Cancer patients have a high symptom burden, many of which may overlap with symptoms of TD. Treatment of TD in cancer patients may provide benefit in various aspects of health including functional outcomes, quality of life, and cancer-induced cachexia. Given the impact of TD in cancer patients, the authors believe it reasonable to assess for TD in men with cancer and hypogonadal symptoms and consider trial of TRT as a shared decision-making approach with close monitoring of adverse events and side effects.
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Metadaten
Titel
Testosterone Therapy in Oncologic Patients
verfasst von
Emily Solsrud
Marne Louters
Amy Pearlman
Publikationsdatum
08.02.2023
Verlag
Springer US
Erschienen in
Current Sexual Health Reports / Ausgabe 1/2023
Print ISSN: 1548-3584
Elektronische ISSN: 1548-3592
DOI
https://doi.org/10.1007/s11930-022-00351-w

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