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Current Cardiology Reports OnlineFirst articles

29.05.2024 | Interventional Cardiology (SR Bailey and T Helmy, Section Editors)

Distinct Challenges of Eruptive and Non-Eruptive Calcified Nodules in Percutaneous Coronary Intervention

Calcified nodules (CN) are thought to be the least common morphology sub-type among the atherosclerotic, calcified or non-calcified, lesions. The prevalence of CN, however, has been reported as 16% per vessel and 30% per patient in the non-culprit …

verfasst von:
Keyvan Karimi Galougahi, Doosup Shin, Ali Dakroub, Koshiro Sakai, Mandeep Singh, Sarah Malik, Akiko Maehara, Mitsuaki Matsumura, Gary Mintz, James C. Spratt, Omar Khalique, Evan Shlofmitz, Allen Jeremias, Richard Shlofmitz, Ziad A. Ali

28.05.2024 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Role of Cyp2c19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

Following percutaneous coronary intervention (PCI), patients are typically prescribed dual antiplatelet therapy (DAPT) consisting of aspirin and a P2Y12 inhibitor: either clopidogrel, ticagrelor or prasugrel. Of these, clopidogrel (Plavix), which …

verfasst von:
Manu Rajachandran, Richard A. Lange

28.05.2024 | Nuclear Cardiology (V Dilsizian, Section Editor)

Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes

With an estimated prevalence of 26% among adults in the United States (US), obstructive sleep apnea (OSA) is exceedingly common [ 1 ]. OSA elevates the risk of mortality and other adverse health outcomes, particularly those related to …

verfasst von:
Ehimen C. Aneni, Albert J. Sinusas, Morgan C. Emokpae, Stephanie L. Thorn, H. Klar Yaggi, Edward J. Miller

28.05.2024 | Interventional Cardiology (SR Bailey and T Helmy, Section Editors)

Infection of Transcatheter Valvular Devices

Transcatheter Aortic Valve Replacement (TAVR) has emerged as the standard of care for patients with symptomatic severe aortic stenosis, regardless of their surgical risk [ 1 – 5 ]. As TAVR is increasingly utilized in younger and lower risk patients …

verfasst von:
Taha Hatab, Syed Zaid, Samarthkumar J. Thakkar, Rody G. Bou Chaaya, Sachin S. Goel, Michael J. Reardon

24.05.2024 | Valvular Heart Disease (TL Kiefer, Section Editor)

Evaluation and Management of Mechanical Heart Valve Dysfunction and Thrombosis

Bioprosthetic valve replacement has increased, in part due to the availability of transcatheter-based valve-in-valve treatment options [ 1 ]. However, mechanical heart valves (MHVs) remain important in younger patients, in whom the objective to …

verfasst von:
Gary Parizher, Ambreen Ali, Paul C. Cremer

22.05.2024 | Nuclear Cardiology (V Dilsizian, Section Editor)

Inflammation and Myocardial Blood Flow in Cardiac Sarcoidosis

Sarcoidosis is commonly denoted as an autoimmune and systemic granulomatous disease that can affect any organ with preference to affect perihilar-mediastinal lymph nodes and lungs [ 1 •]. Substantial research outlines an interplay of environmental …

verfasst von:
Ashwin Singh Parihar, Ines Valenta, Salwa Mikhail, Alessio Imperiale, Thomas H. Schindler

16.05.2024 | Invasive Electrophysiology and Pacing (EK Heist, Section Editor)

Artificial Intelligence Interpretation of the Electrocardiogram: A State-of-the-Art Review

Electrocardiography (ECG) is a ubiquitous diagnostic test which can genuinely be considered an extension of the cardiovascular physical examination. ECG gathers standardized, reproducible, and unadulterated physiological data, free from human …

verfasst von:
Benjamin Ose, Zeeshan Sattar, Amulya Gupta, Christian Toquica, Chris Harvey, Amit Noheria

Open Access 16.05.2024 | Echocardiography (JM Gardin and AH Waller, Section Editors)

The Role of Multimodality Imaging in Cardiomyopathy

The prevalence of heart failure (HF) continues to grow globally with increasing financial burden worldwide. In 2017, there were 64.3 million people with HF globally [ 1 ] and 1.2 million HF admissions in the United States (US) alone [ 2 ]. The …

verfasst von:
Jonathan A. Pan, Amit R. Patel

15.05.2024 | Cardiac PET, CT, and MRI (P Cremer, Section Editor)

Assessing Regurgitation Severity, Adverse Remodeling, and Fibrosis with CMR in Primary Mitral Regurgitation

Mitral regurgitation (MR) is a common valvular heart disease both in the United States and worldwide with a prevalence of more than 10% in the population older than 75 years of age [ 1 – 3 ]. Population-based outcomes studies have demonstrated that …

verfasst von:
Amr Darwish, Akila Bersali, Mujtaba Saeed, Aneesh Dhore, Dimitrios Maragiannis, K. Carlos El-Tallawi, Dipan J. Shah

14.05.2024 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Polyvascular Disease: A Narrative Review of Risk Factors, Clinical Outcomes and Treatment

Polyvascular disease is the presence of atherosclerosis in at least two distinct vascular territories, most commonly resulting in coronary artery disease (CAD), cerebrovascular disease (CVD) and lower extremity peripheral artery disease (PAD) …

verfasst von:
Manasi Tannu, Connie N. Hess, J. Antonio Gutierrez, Renato Lopes, Rajesh V. Swaminathan, S. Elissa Altin, Sunil V. Rao

09.05.2024 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Routine Functional Testing or Standard Care in High-Risk Patients after Percutaneous Coronary Intervention

Chronic coronary disease patients with high-risk clinical and anatomical criteria undergoing percutaneous coronary intervention (PCI) are at increased risk of future cardiovascular events, necessitating regular follow-up visits post-PCI.

verfasst von:
Nouman Arshad, Indah Sukmawati, Upul Wickramarachchi, Shrilla Banerjee, Fathima Aaysha Cader

07.05.2024 | Ischemic Heart Disease (D Mukherjee, Section Editor)

Social Isolation, Loneliness, and Cardiovascular Mortality: The Role of Health Care System Interventions

Humans have found themselves at a new peak of loneliness in an advancing world. Loneliness is a subjective measure defined as an incongruity between a person’s desired and actual social relationships [ 1 ]. The prevalence of loneliness among the …

verfasst von:
Syed Mohammed Usama, Yash Lalit Kothari, Aditya Karthikeyan, Syed Anjum Khan, Mohammad Sarraf, Vinayak Nagaraja

Open Access 07.05.2024 | Cardiovascular Critical Care (A Higgins and R Lee, Section Editors)

Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology

Cardiogenic shock (CS) is a complex and heterogeneous disorder characterized by a low-cardiac output state, resulting in a condition of life-threatening end-organ hypoperfusion and often culminating in multi-organ failure [ 1 ].

verfasst von:
I. Protti, M. P. J. van Steenwijk, P. Meani, L. Fresiello, C. L. Meuwese, D. W. Donker

02.05.2024 | Peripheral Vascular Disease (S Kinlay, Section Editor)

Medical Therapy for Peripheral Artery Disease

Peripheral artery disease (PAD) commonly refers to occlusive atherosclerotic disease of the lower extremities. The prevalence of lower extremity PAD is rising as a result of increasing age and prevalence of cardiovascular (CV) risk factors such as …

verfasst von:
Mario Enrico Canonico, Connie N. Hess, R. Kevin Rogers, Marc P. Bonaca

29.04.2024 | New Therapies for Cardiovascular Disease (AA Bavry and MR Massoomi, Section Editors)

Use of Virtual Reality and 3D Models in Contemporary Practice of Cardiology

Virtual reality (VR) is the visualization of digital information in three dimensions. VR is a simulated experience created by realistically generated images and sounds. Invented in the 1950s [ 1 , 2 ], significant advancements emerged in the 1980s …

verfasst von:
Iva Minga, Mohammad A. Al-Ani, Sarah Moharem-Elgamal, Aswathy Vaikom House MD, Ahmed Sami Abuzaid MD, Michael Masoomi, Saima Mangi

24.04.2024 | Nuclear Cardiology (V Dilsizian, Section Editor)

Chagas Cardiomyopathy and Myocardial Sympathetic Denervation

Chagas disease (CD) is one of the most common yet neglected tropical diseases, affecting around 6 to 7 million people in the world. It is estimated that approximately 70 million people are at risk of exposure to Trypanosoma cruzi infection in 21 …

verfasst von:
Leonardo Pippa Gadioli, André Schmidt, Benedito Carlos Maciel, Gustavo Jardim Volpe, Marcus Vinicius Simões, José Antonio Marin-Neto

24.04.2024 | Structural Heart Disease (S Vakamudi, Section Editor)

Evidence-Based Update on Transcatheter Therapies for Pulmonary Embolism

Pulmonary embolism (PE) is estimated to result in approximately 100,000 annual deaths in the United States with 30-day and 1-year mortality of approximately 4 and 13 percent, respectively [ 1 , 2 ]. Treatment of pulmonary embolism is estimated to …

verfasst von:
Peter Monteleone, Akash Patel, Jonathan Paul

Open Access 22.04.2024 | Echocardiography (JM Gardin and AH Waller, Section Editors)

Evolving Applications of Echocardiography in the Evaluation of Left Atrial and Right Ventricular Strain

Left ventricular (LV) strain is widely used in the detection of subclinical LV dysfunction (e.g., cancer treatment-related cardiac dysfunction), heart failure with preserved ejection fraction (HFpEF), the assessment of LV diastolic dysfunction …

verfasst von:
Adam Serafin, Wojciech Kosmala, Thomas H. Marwick

18.04.2024 | Diabetes and Cardiovascular Disease (D Bruemmer, Section Editor)

Unexplained Residual Risk In Type 2 Diabetes: How Big Is The Problem?

Type 2 diabetes (T2D) is a major health care problem in the US, affecting approximately 37 million Americans or ~ 10% of the adult population, and for every person with T2D, there ~ 2 individuals with prediabetes [ 1 ]. Cardiovascular disease (CVD) …

verfasst von:
Sivaram Neppala, Jemema Rajan, Eric Yang, Ralph A. DeFronzo

16.04.2024 | Interventional Cardiology (SR Bailey and T Helmy, Section Editors)

Occupational Risks of Radiation Exposure to Cardiologists

In recent years, the field of invasive cardiology has seen tremendous evolution. Technological advances have allowed practitioners to intervene in increasingly complex and intricate cases [ 1 , 2 •]. Difficult procedures, however, can mean longer …

verfasst von:
Jean-Benoît Veillette, Marc-Antoine Carrier, Stéphane Rinfret, Julien Mercier, Jean Arsenault, Jean-Michel Paradis