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Erschienen in: Journal of Bone and Mineral Metabolism 1/2024

09.01.2024 | Original Article

Psoas muscle area is associated with prognosis in elderly patients with hip fracture

verfasst von: Seong-Eun Byun, Jin-Woo Kim, Jeongmo Koo, Soonchul Lee

Erschienen in: Journal of Bone and Mineral Metabolism | Ausgabe 1/2024

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Abstract

Introduction

Sarcopenia is a key predictor of prognosis in patients with hip fractures. This study utilized computed tomography (CT) scan (1) to determine the association between psoas muscle cross-sectional area (CSA) and mortality, along with other muscles, and (2) to confirm the correlation between muscle CSA and appendicular lean mass (ALM) measured using DXA in elderly patients with hip fracture.

Materials and methods

Patients who were aged ≥ 50 years and underwent surgical treatment for hip fracture were eligible for this study. After a series of exclusion criteria, 217 female patients were included. Patient data, including clinical characteristics, such as body mass index (BMI), CSA, and ALM, were retrospectively collected. The Kaplan–Meier survival method and Cox proportional hazards regression analysis were used for the statistical analyses. The correlation between CSA/BMI and ALM was also assessed.

Results

Patients in the lowest quartile of psoas muscle CSA/BMI had shorter survival times than those in the other quartiles. When the Cox proportional hazards regression analysis was adjusted for multiple variables, the lowest quartile of the CSA/BMI of the psoas was a risk factor for mortality. The CSA/BMI of the psoas showed the highest correlation coefficient. The CSA/BMI ratio of the other muscles showed a moderately positive correlation with ALM.

Conclusion

The CSA of the psoas is associated with prognosis in elderly patients with hip fractures and shows a moderately positive correlation with ALM. Hence, the CSA of psoas is useful for predicting survival and muscle mass in elderly patients with hip fractures.
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Literatur
1.
Zurück zum Zitat Chen Y-P, Wong P-K, Tsai M-J, Chang W-C, Hsieh T-S et al (2020) The high prevalence of sarcopenia and its associated outcomes following hip surgery in Taiwanese geriatric patients with a hip fracture. J Formos Med Assoc 119:1807–1816CrossRefPubMed Chen Y-P, Wong P-K, Tsai M-J, Chang W-C, Hsieh T-S et al (2020) The high prevalence of sarcopenia and its associated outcomes following hip surgery in Taiwanese geriatric patients with a hip fracture. J Formos Med Assoc 119:1807–1816CrossRefPubMed
2.
Zurück zum Zitat Ji H-M, Han J, Jin DS, Suh H, Chung Y-S, Won Y-Y (2016) Sarcopenia and sarcopenic obesity in patients undergoing orthopedic surgery. Clin Orhop Surg 8:194–202CrossRef Ji H-M, Han J, Jin DS, Suh H, Chung Y-S, Won Y-Y (2016) Sarcopenia and sarcopenic obesity in patients undergoing orthopedic surgery. Clin Orhop Surg 8:194–202CrossRef
3.
Zurück zum Zitat Landi F, Calvani R, Ortolani E, Salini S, Martone AM et al (2017) The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation. Osteoporos Int 28:1569–1576CrossRefPubMed Landi F, Calvani R, Ortolani E, Salini S, Martone AM et al (2017) The association between sarcopenia and functional outcomes among older patients with hip fracture undergoing in-hospital rehabilitation. Osteoporos Int 28:1569–1576CrossRefPubMed
5.
Zurück zum Zitat Cesari M, Fielding RA, Pahor M, Goodpaster B, Hellerstein M et al (2012) Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia. J Cachexia Sarcopenia Muscle 3:181–190CrossRefPubMedPubMedCentral Cesari M, Fielding RA, Pahor M, Goodpaster B, Hellerstein M et al (2012) Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia. J Cachexia Sarcopenia Muscle 3:181–190CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Moon SW, Lee SH, Woo A, Leem AY, Lee SH, Chung KS, Kim EY, Jung JY, Kang YA, Park MS, Kim YS, Kim CO, Kim SY (2022) Reference values of skeletal muscle area for diagnosis of sarcopenia using chest computed tomography in Asian general population. J Cachexia Sarcopenia Muscle 13:955–965CrossRefPubMedPubMedCentral Moon SW, Lee SH, Woo A, Leem AY, Lee SH, Chung KS, Kim EY, Jung JY, Kang YA, Park MS, Kim YS, Kim CO, Kim SY (2022) Reference values of skeletal muscle area for diagnosis of sarcopenia using chest computed tomography in Asian general population. J Cachexia Sarcopenia Muscle 13:955–965CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Byun S-E, Kim S, Kim K-H, Ha Y-C (2019) Psoas cross-sectional area as a predictor of mortality and a diagnostic tool for sarcopenia in hip fracture patients. J Bone Miner Metab 37:871–879CrossRefPubMed Byun S-E, Kim S, Kim K-H, Ha Y-C (2019) Psoas cross-sectional area as a predictor of mortality and a diagnostic tool for sarcopenia in hip fracture patients. J Bone Miner Metab 37:871–879CrossRefPubMed
8.
Zurück zum Zitat Englesbe MJ, Patel SP, He K, Lynch RJ, Schaubel DE et al (2010) Sarcopenia and mortality after liver transplantation. J Am Coll Surg 211:271–278CrossRefPubMedPubMedCentral Englesbe MJ, Patel SP, He K, Lynch RJ, Schaubel DE et al (2010) Sarcopenia and mortality after liver transplantation. J Am Coll Surg 211:271–278CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Hervochon R, Bobbio A, Guinet C, Mansuet-Lupo A, Rabbat A et al (2017) Body mass index and total psoas area affect outcomes in patients undergoing pneumonectomy for cancer. Ann Thorac Surg 103:287–295CrossRefPubMed Hervochon R, Bobbio A, Guinet C, Mansuet-Lupo A, Rabbat A et al (2017) Body mass index and total psoas area affect outcomes in patients undergoing pneumonectomy for cancer. Ann Thorac Surg 103:287–295CrossRefPubMed
10.
Zurück zum Zitat Prado CM, Lieffers JR, McCargar LJ, Reiman T, Sawyer MB et al (2008) Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol 9:629–635CrossRefPubMed Prado CM, Lieffers JR, McCargar LJ, Reiman T, Sawyer MB et al (2008) Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol 9:629–635CrossRefPubMed
11.
Zurück zum Zitat Rutten IJ, Ubachs J, Kruitwagen RF, Beets-Tan RG, Olde Damink SW, Van Gorp T (2017) Psoas muscle area is not representative of total skeletal muscle area in the assessment of sarcopenia in ovarian cancer. J Cachexia Sarcopenia Muscle 8:630–8CrossRefPubMedPubMedCentral Rutten IJ, Ubachs J, Kruitwagen RF, Beets-Tan RG, Olde Damink SW, Van Gorp T (2017) Psoas muscle area is not representative of total skeletal muscle area in the assessment of sarcopenia in ovarian cancer. J Cachexia Sarcopenia Muscle 8:630–8CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR et al (2018) Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle 9:1053–1062CrossRefPubMedPubMedCentral Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR et al (2018) Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle 9:1053–1062CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Durand F, Buyse S, Francoz C, Laouénan C, Bruno O et al (2014) Prognostic value of muscle atrophy in cirrhosis using psoas muscle thickness on computed tomography. J Hepatol 60:1151–1157CrossRefPubMed Durand F, Buyse S, Francoz C, Laouénan C, Bruno O et al (2014) Prognostic value of muscle atrophy in cirrhosis using psoas muscle thickness on computed tomography. J Hepatol 60:1151–1157CrossRefPubMed
14.
Zurück zum Zitat Sim J-H, Lee S-H, Kim J-W, Koh W-U, Kim H-T et al (2021) Low psoas lumbar vertebral index is associated with mortality after hip fracture surgery in elderly patients: A retrospective analysis. J Pers Med 11:673CrossRefPubMedPubMedCentral Sim J-H, Lee S-H, Kim J-W, Koh W-U, Kim H-T et al (2021) Low psoas lumbar vertebral index is associated with mortality after hip fracture surgery in elderly patients: A retrospective analysis. J Pers Med 11:673CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Looijaard SM, Maier AB, Voskuilen AF, Van Zanten T, Bouman DE et al (2020) Are computed tomography-based measures of specific abdominal muscle groups predictive of adverse outcomes in older cancer patients? Heliyon 6:e05437CrossRefPubMedPubMedCentral Looijaard SM, Maier AB, Voskuilen AF, Van Zanten T, Bouman DE et al (2020) Are computed tomography-based measures of specific abdominal muscle groups predictive of adverse outcomes in older cancer patients? Heliyon 6:e05437CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR et al (2014) The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci 69:547–558CrossRefPubMedPubMedCentral Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR et al (2014) The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci 69:547–558CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Tang T-C, Hwang A-C, Liu L-K, Lee W-J, Chen L-Y et al (2018) FNIH-defined sarcopenia predicts adverse outcomes among community-dwelling older people in Taiwan: results from I-Lan longitudinal aging study. J Gerontol A Biol Sci Med Sci 73:828–834CrossRefPubMed Tang T-C, Hwang A-C, Liu L-K, Lee W-J, Chen L-Y et al (2018) FNIH-defined sarcopenia predicts adverse outcomes among community-dwelling older people in Taiwan: results from I-Lan longitudinal aging study. J Gerontol A Biol Sci Med Sci 73:828–834CrossRefPubMed
Metadaten
Titel
Psoas muscle area is associated with prognosis in elderly patients with hip fracture
verfasst von
Seong-Eun Byun
Jin-Woo Kim
Jeongmo Koo
Soonchul Lee
Publikationsdatum
09.01.2024
Verlag
Springer Nature Singapore
Erschienen in
Journal of Bone and Mineral Metabolism / Ausgabe 1/2024
Print ISSN: 0914-8779
Elektronische ISSN: 1435-5604
DOI
https://doi.org/10.1007/s00774-023-01485-0

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