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European Journal of Nuclear Medicine and Molecular Imaging

Erschienen in:

12.12.2023 | Short Communication

Ultra-fast whole-body bone tomoscintigraphies achieved with a high-sensitivity 360° CZT camera and a dedicated deep-learning noise reduction algorithm

verfasst von: Achraf Bahloul, Antoine Verger, Yechiel Lamash, Nathaniel Roth, Diawad Dari, Pierre-Yves Marie, Laetitia Imbert

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 5/2024

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Abstract

This study aimed to determine whether the whole-body bone Single Photon Emission Computed Tomography (SPECT) recording times of around 10 min, routinely provided by a high-sensitivity 360° cadmium and zinc telluride (CZT) camera, can be further reduced by a deep-learning noise reduction (DLNR) algorithm.

Methods

DLNR was applied on whole-body images recorded after the injection of 545 ± 33 MBq of [^99mTc]Tc-HDP in 19 patients (14 with bone metastasis) and reconstructed with 100%, 90%, 80%, 70%, 60%, 50%, 40%, and 30% of the original SPECT recording times.

Results

Irrespective of recording time, DLNR enhanced the contrast-to-noise ratios and slightly decreased the standardized uptake values of bone lesions. Except in one markedly obese patient, the quality of DLNR processed images remained good-to-excellent down to 60% of the recording time, corresponding to around 6 min SPECT-recording.

Conclusion

Ultra-fast SPECT recordings of 6 min can be achieved when DLNR is applied on whole-body bone 360° CZT-SPECT.

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Melki S, Chawki MB, Marie P-Y, Imbert L, Verger A. Augmented planar bone scintigraphy obtained from a whole-body SPECT recording of less than 20 min with a high-sensitivity 360° CZT camera. Eur J Nucl Med Mol Imaging. 2020;47:1329–31.CrossRefPubMed

Bahloul A, Verger A, Blum A, Chawki MB, Perrin M, Melki S, et al. Bone scintigraphy of vertebral fractures with a whole-body CZT camera in a PET-like utilization. Front Nucl Med [Internet]. 2021 [cited 2023 Sep 19];1. Available from: https://www.frontiersin.org/articles/10.3389/fnume.2021.740275.

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Titel: Ultra-fast whole-body bone tomoscintigraphies achieved with a high-sensitivity 360° CZT camera and a dedicated deep-learning noise reduction algorithm
verfasst von: Achraf Bahloul
Antoine Verger
Yechiel Lamash
Nathaniel Roth
Diawad Dari
Pierre-Yves Marie
Laetitia Imbert
Publikationsdatum: 12.12.2023
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 5/2024
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-023-06558-w

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Ultra-fast whole-body bone tomoscintigraphies achieved with a high-sensitivity 360° CZT camera and a dedicated deep-learning noise reduction algorithm

Abstract

Methods

Results

Conclusion

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

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Abstract

Methods

Results

Conclusion

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