Ausgabe 4/2020
Inhalt (15 Artikel)
Allogeneic cardiosphere-derived cells (CAP-1002) in critically ill COVID-19 patients: compassionate-use case series
Siddharth Singh, Tarun Chakravarty, Peter Chen, Akbarshakh Akhmerov, Jeremy Falk, Oren Friedman, Tanzira Zaman, Joseph E. Ebinger, Mitch Gheorghiu, Linda Marbán, Eduardo Marbán, Raj R. Makkar
Longitudinal metabolic profiling of cardiomyocytes derived from human-induced pluripotent stem cells
Mohamed M. Bekhite, Andrés González Delgado, Florian Menz, Tom Kretzschmar, Jasmine M. F. Wu, Tarek Bekfani, Sandor Nietzsche, Maria Wartenberg, Martin Westermann, Boris Greber, P. Christian Schulze
Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS
Shanna Hamilton, Radmila Terentyeva, Benjamin Martin, Fruzsina Perger, Jiaoni Li, Andrei Stepanov, Ingrid M. Bonilla, Björn C. Knollmann, Przemyslaw B. Radwański, Sandor Györke, Andriy E. Belevych, Dmitry Terentyev
Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities
Ilona Cuijpers, Steven J. Simmonds, Marc van Bilsen, Elżbieta Czarnowska, Arantxa González Miqueo, Stephane Heymans, Annika R. Kuhn, Paul Mulder, Anna Ratajska, Elizabeth A. V. Jones, Ebba Brakenhielm
Intravenously delivered mesenchymal stem cells prevent microvascular obstruction formation after myocardial ischemia/reperfusion injury
Junzhuo Wang, Ziwei Chen, Qing Dai, Jinxuan Zhao, Zilun Wei, Jiaxin Hu, Xuan Sun, Jun Xie, Biao Xu
Vascular autophagy in health and disease
William E. Hughes, Andreas M. Beyer, David D. Gutterman
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy
Nadine Lubos, Svenja van der Gaag, Muhammed Gerçek, Sebastian Kant, Rudolf E. Leube, Claudia A. Krusche
Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia
Patricia Wischmann, Viktoria Kuhn, Tatsiana Suvorava, Johanna M. Muessig, Jens W. Fischer, Brant E. Isakson, Sebastian M. Haberkorn, Ulrich Flögel, Jürgen Schrader, Christian Jung, Miriam M. Cortese-Krott, Gerd Heusch, Malte Kelm
Interplay of the red blood cell and vascular endothelial nitric oxide synthase system to combat cardiac complications of anemia
Andreas Daiber, Thomas Münzel
Deletion of newly described pro-survival molecule Pellino-1 increases oxidative stress, downregulates cIAP2/NF-κB cell survival pathway, reduces angiogenic response, and thereby aggravates tissue function in mouse ischemic models
Vaithinathan Selvaraju, Mahesh Thirunavukkarasu, Mandip Joshi, Babatunde Oriowo, Inam A. Shaikh, Muhammad Tipu Rishi, Leonidas Tapias, Vladimir Coca-Soliz, Ibnalwalid Saad, Jacob Campbell, Seetur R. Pradeep, Santosh Swaminathan, Siu-Pok Yee, David W. McFadden, J. Alexander Palesty, Nilanjana Maulik
The inotropic agent digitoxin strengthens desmosomal adhesion in cardiac myocytes in an ERK1/2-dependent manner
Camilla Schinner, Silvana Olivares-Florez, Angela Schlipp, Sebastian Trenz, Manouk Feinendegen, Heinrich Flaswinkel, Ellen Kempf, Desalegn Tadesse Egu, Sunil Yeruva, Jens Waschke
Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis
Ann-Kathrin Vlacil, Jutta Schuett, Volker Ruppert, Muhidien Soufi, Raghav Oberoi, Kinan Shahin, Christian Wächter, Thomas Tschernig, Yu Lei, Fan Liu, Uwe J. F. Tietge, Bernhard Schieffer, Harald Schuett, Karsten Grote
Secreted frizzled-related protein 2, a novel mechanism to induce myocardial ischemic protection through angiogenesis
Dorothy E. Vatner, Marko Oydanich, Jie Zhang, Denis Babici, Stephen F. Vatner
Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling
Satadru K. Lahiri, Ann P. Quick, Benoit Samson-Couterie, Mohit Hulsurkar, Ies Elzenaar, Ralph J. van Oort, Xander H. T. Wehrens
Remote ischemic preconditioning reduces myocardial ischemia–reperfusion injury through unacylated ghrelin-induced activation of the JAK/STAT pathway
Yasuaki Sawashita, Naoyuki Hirata, Yusuke Yoshikawa, Hirofumi Terada, Yasuyuki Tokinaga, Michiaki Yamakage