Skip to main content
Erschienen in: Lasers in Medical Science 1/2024

01.12.2024 | Review Article

Complication rates and safety of pulsed dye laser treatment for port-wine stain: a systematic review and meta-analysis

verfasst von: Meng dong Shi, Kun Yang, Shu bo Li, Qian Zhao, Ran Huo, Cong Fu

Erschienen in: Lasers in Medical Science | Ausgabe 1/2024

Einloggen, um Zugang zu erhalten

Abstract

Pulsed dye laser (PDL) is the most commonly used method for port-wine stain (PWS); however, no studies have reported the safety of PDL. This review aimed to collect and summarize complications reported in relevant literature, assess complication rates in treating PWS with PDL, and explore the relevant influencing factors. A systematic review and meta-analysis were conducted to search for related studies in PubMed, Embase, and the Cochrane Library until August 2022. Two reviewers independently evaluated the risk of bias of included studies. Stata Software version 17.0 was used for the analysis. All complications reported in the literature are divided into acute phase complications and long-term complications. Overall pooled purpura, edema, crusting, blistering, hyperpigmentation, hypopigmentation, and scarring rates were 98.3%, 97.6%, 21.5%, 8.7%, 12.8%, 0.9%, and 0.2%, respectively. Although the acute adverse reactions were found to be common, the long-term permanent complications clearly have a lower frequency, and the occurrence of scarring is much lower than that initially thought. This indicates that effective protective measures after treatment are very important for preventing scar formation. Overall, PDL treatment for PWS shows a high level of safety and low chances of causing long-term complications.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Jacobs AH, Walton RG (1976) The incidence of birthmarks in the neonate. Pediatrics 58(2):218–222PubMedCrossRef Jacobs AH, Walton RG (1976) The incidence of birthmarks in the neonate. Pediatrics 58(2):218–222PubMedCrossRef
2.
Zurück zum Zitat Wanitphakdeedecha R, Ng JNC, Yan C, Manuskiatti W, Sudhipongpracha T, Jantarakolica T (2021) Quality of Life and Psychological Effects of Port-Wine Stain: A Review of Literature. Clin Cosmet Investig Dermatol 14:681–690PubMedPubMedCentralCrossRef Wanitphakdeedecha R, Ng JNC, Yan C, Manuskiatti W, Sudhipongpracha T, Jantarakolica T (2021) Quality of Life and Psychological Effects of Port-Wine Stain: A Review of Literature. Clin Cosmet Investig Dermatol 14:681–690PubMedPubMedCentralCrossRef
3.
Zurück zum Zitat Lanigan SW, Cotterill JA (1989) Psychological disabilities amongst patients with port wine stains. Br J Dermatol 121(2):209–215PubMedCrossRef Lanigan SW, Cotterill JA (1989) Psychological disabilities amongst patients with port wine stains. Br J Dermatol 121(2):209–215PubMedCrossRef
4.
Zurück zum Zitat Lanigan SW, Taibjee SM (2004) Recent advances in laser treatment of port-wine stains. Br J Dermatol 151(3):527–533PubMedCrossRef Lanigan SW, Taibjee SM (2004) Recent advances in laser treatment of port-wine stains. Br J Dermatol 151(3):527–533PubMedCrossRef
5.
Zurück zum Zitat Cinkara G, Langbroek GB, van der Horst CMAM, Wolkerstorfer A, Horbach SER, Ubbink DT (2021) Therapeutic Strategies for Untreated Capillary Malformations of the Head and Neck Region: A Systematic Review and Meta-Analyses. Am J Clin Dermatol 22(5):603–614PubMedPubMedCentralCrossRef Cinkara G, Langbroek GB, van der Horst CMAM, Wolkerstorfer A, Horbach SER, Ubbink DT (2021) Therapeutic Strategies for Untreated Capillary Malformations of the Head and Neck Region: A Systematic Review and Meta-Analyses. Am J Clin Dermatol 22(5):603–614PubMedPubMedCentralCrossRef
6.
Zurück zum Zitat Snast I, Lapidoth M, Kaftory R, Nosrati A, Hodak E, Mimouni D et al (2021) Does interval time between pulsed dye laser treatments for port-wine stains influence outcome? A systematic review and meta-analysis. Lasers Med Sci 36(9):1909–1916PubMedCrossRef Snast I, Lapidoth M, Kaftory R, Nosrati A, Hodak E, Mimouni D et al (2021) Does interval time between pulsed dye laser treatments for port-wine stains influence outcome? A systematic review and meta-analysis. Lasers Med Sci 36(9):1909–1916PubMedCrossRef
7.
Zurück zum Zitat Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700PubMedPubMedCentralCrossRef Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700PubMedPubMedCentralCrossRef
8.
Zurück zum Zitat Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J (2003) Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg 73(9):712–716PubMedCrossRef Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J (2003) Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg 73(9):712–716PubMedCrossRef
9.
Zurück zum Zitat Li D, Chen B, Zhang H, Yuan Y, Fan W, Ying Z (2020) Retrospective study of the treatment of port-wine stains with 595-nm pulsed dye laser in 261 Chinese patients. Lasers Med Sci 35(8):1811–1819PubMedCrossRef Li D, Chen B, Zhang H, Yuan Y, Fan W, Ying Z (2020) Retrospective study of the treatment of port-wine stains with 595-nm pulsed dye laser in 261 Chinese patients. Lasers Med Sci 35(8):1811–1819PubMedCrossRef
10.
Zurück zum Zitat Yu W, Ma G, Qiu Y, Chen H, Jin Y, Yang X et al (2015) Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain. Br J Dermatol 172(3):684–691PubMedCrossRef Yu W, Ma G, Qiu Y, Chen H, Jin Y, Yang X et al (2015) Prospective comparison treatment of 595-nm pulsed-dye lasers for virgin port-wine stain. Br J Dermatol 172(3):684–691PubMedCrossRef
11.
Zurück zum Zitat Lin M-Y, Lin C-S, Hu S, Chang J-M, Chung W-H, Zhang Z-Y et al (2019) The application of 595-nm pulsed dye laser for vascular anomalies in a Chinese population: a 10-year experience. J Cosmet Laser Ther 21(3):171–178PubMedCrossRef Lin M-Y, Lin C-S, Hu S, Chang J-M, Chung W-H, Zhang Z-Y et al (2019) The application of 595-nm pulsed dye laser for vascular anomalies in a Chinese population: a 10-year experience. J Cosmet Laser Ther 21(3):171–178PubMedCrossRef
12.
Zurück zum Zitat Khandpur S, Sharma VK (2016) Assessment of Efficacy of the 595-nm Pulsed Dye Laser in the Treatment of Facial Port-Wine Stains in Indian Patients. Dermatol Surg 42(6):717–726PubMedCrossRef Khandpur S, Sharma VK (2016) Assessment of Efficacy of the 595-nm Pulsed Dye Laser in the Treatment of Facial Port-Wine Stains in Indian Patients. Dermatol Surg 42(6):717–726PubMedCrossRef
13.
Zurück zum Zitat Yu W, Wang T, Zhu J, Qiu Y, Chen H, Jin Y et al (2018) EMLA cream does not influence efficacy and pain reduction during pulsed-dye laser treatment of port-wine stain: a prospective side-by-side comparison. Lasers Med Sci 33(3):573–579PubMedCrossRef Yu W, Wang T, Zhu J, Qiu Y, Chen H, Jin Y et al (2018) EMLA cream does not influence efficacy and pain reduction during pulsed-dye laser treatment of port-wine stain: a prospective side-by-side comparison. Lasers Med Sci 33(3):573–579PubMedCrossRef
14.
Zurück zum Zitat Faurschou A, Togsverd-Bo K, Zachariae C, Haedersdal M (2009) Pulsed dye laser vs. intense pulsed light for port-wine stains: a randomized side-by-side trial with blinded response evaluation. Br J Dermatol 160(2):359–364PubMedCrossRef Faurschou A, Togsverd-Bo K, Zachariae C, Haedersdal M (2009) Pulsed dye laser vs. intense pulsed light for port-wine stains: a randomized side-by-side trial with blinded response evaluation. Br J Dermatol 160(2):359–364PubMedCrossRef
15.
Zurück zum Zitat El Ezzi O, Tessa M, Pierluigi B, de Buys Roessingh AS (2020) Is it better to reduce the intervals between pulsed dye laser treatments for port wine stains in children? Laser Doppler Imaging based study. J Pediatr Surg 55(11):2459–2465PubMedCrossRef El Ezzi O, Tessa M, Pierluigi B, de Buys Roessingh AS (2020) Is it better to reduce the intervals between pulsed dye laser treatments for port wine stains in children? Laser Doppler Imaging based study. J Pediatr Surg 55(11):2459–2465PubMedCrossRef
16.
Zurück zum Zitat Yu W, Ying H, Chen Y, Qiu Y, Chen H, Jin Y et al (2017) In Vivo Investigation of the Safety and Efficacy of Pulsed Dye Laser with Two Spot Sizes in Port-Wine Stain Treatment: A Prospective Side-by-Side Comparison. Photomed Laser Surg 35(9):465–471PubMedCrossRef Yu W, Ying H, Chen Y, Qiu Y, Chen H, Jin Y et al (2017) In Vivo Investigation of the Safety and Efficacy of Pulsed Dye Laser with Two Spot Sizes in Port-Wine Stain Treatment: A Prospective Side-by-Side Comparison. Photomed Laser Surg 35(9):465–471PubMedCrossRef
17.
Zurück zum Zitat Shi W, Wang J, Lin Y, Geng J, Wang H, Gong Y et al (2014) Treatment of port wine stains with pulsed dye laser: a retrospective study of 848 cases in Shandong Province, People's Republic of China. Drug Des Devel Ther 8:2531–2538PubMedPubMedCentral Shi W, Wang J, Lin Y, Geng J, Wang H, Gong Y et al (2014) Treatment of port wine stains with pulsed dye laser: a retrospective study of 848 cases in Shandong Province, People's Republic of China. Drug Des Devel Ther 8:2531–2538PubMedPubMedCentral
18.
Zurück zum Zitat Swan BC, Robertson SJ, Tuxen A, Ma E, Yip L, Ly L et al (2017) Pulsed dye laser treatment of capillary malformations in infants at 2-weekly versus 3-monthly intervals, reducing the need for general anaesthesia. Australas J Dermatol 58(3):214–218PubMedCrossRef Swan BC, Robertson SJ, Tuxen A, Ma E, Yip L, Ly L et al (2017) Pulsed dye laser treatment of capillary malformations in infants at 2-weekly versus 3-monthly intervals, reducing the need for general anaesthesia. Australas J Dermatol 58(3):214–218PubMedCrossRef
19.
Zurück zum Zitat Jeon H, Bernstein LJ, Belkin DA, Ghalili S, Geronemus RG (2019) Pulsed Dye Laser Treatment of Port-Wine Stains in Infancy Without the Need for General Anesthesia. JAMA Dermatol 155(4):435–441PubMedPubMedCentralCrossRef Jeon H, Bernstein LJ, Belkin DA, Ghalili S, Geronemus RG (2019) Pulsed Dye Laser Treatment of Port-Wine Stains in Infancy Without the Need for General Anesthesia. JAMA Dermatol 155(4):435–441PubMedPubMedCentralCrossRef
20.
Zurück zum Zitat Fallahi M, Hallaji Z, Tavakolpour S, Niknam S, Salehi Farid A, Nili A et al (2021) Evaluating the efficacy and safety of topical sirolimus 0.2% cream as adjuvant therapy with pulsed dye laser for the treatment of port wine stain: A randomized, double-blind, placebo-controlled trial. J Cosmet Dermatol 20(8):2498–2506PubMedCrossRef Fallahi M, Hallaji Z, Tavakolpour S, Niknam S, Salehi Farid A, Nili A et al (2021) Evaluating the efficacy and safety of topical sirolimus 0.2% cream as adjuvant therapy with pulsed dye laser for the treatment of port wine stain: A randomized, double-blind, placebo-controlled trial. J Cosmet Dermatol 20(8):2498–2506PubMedCrossRef
21.
Zurück zum Zitat Asahina A, Watanabe T, Kishi A, Hattori N, Shirai A, Kagami S et al (2006) Evaluation of the treatment of port-wine stains with the 595-nm long pulsed dye laser: a large prospective study in adult Japanese patients. J Am Acad Dermatol 54(3):487–493PubMedCrossRef Asahina A, Watanabe T, Kishi A, Hattori N, Shirai A, Kagami S et al (2006) Evaluation of the treatment of port-wine stains with the 595-nm long pulsed dye laser: a large prospective study in adult Japanese patients. J Am Acad Dermatol 54(3):487–493PubMedCrossRef
22.
Zurück zum Zitat Yu W, Zhu J, Changc S-J, Chen H, Jin Y, Yang X et al (2018) Shorter Treatment Intervals of East Asians with Port-Wine Stain with Pulsed Dye Laser Are Safe and Effective-A Prospective Side-by-Side Comparison. Photomed Laser Surg 36(1):37–43PubMedCrossRef Yu W, Zhu J, Changc S-J, Chen H, Jin Y, Yang X et al (2018) Shorter Treatment Intervals of East Asians with Port-Wine Stain with Pulsed Dye Laser Are Safe and Effective-A Prospective Side-by-Side Comparison. Photomed Laser Surg 36(1):37–43PubMedCrossRef
23.
Zurück zum Zitat Anolik R, Newlove T, Weiss ET, Brightman L, Hale EK, Karen JK et al (2012) Investigation into optimal treatment intervals of facial port-wine stains using the pulsed dye laser. J Am Acad Dermatol 67(5):985–990PubMedCrossRef Anolik R, Newlove T, Weiss ET, Brightman L, Hale EK, Karen JK et al (2012) Investigation into optimal treatment intervals of facial port-wine stains using the pulsed dye laser. J Am Acad Dermatol 67(5):985–990PubMedCrossRef
24.
Zurück zum Zitat Wang T, Chen D, Yang J, Ma G, Yu W, Lin X (2018) Safety and efficacy of dual-wavelength laser (1064 + 595 nm) for treatment of non-treated port-wine stains. J Eur Acad Dermatol Venereol 32(2):260–264PubMedCrossRef Wang T, Chen D, Yang J, Ma G, Yu W, Lin X (2018) Safety and efficacy of dual-wavelength laser (1064 + 595 nm) for treatment of non-treated port-wine stains. J Eur Acad Dermatol Venereol 32(2):260–264PubMedCrossRef
25.
Zurück zum Zitat Tremaine AM, Armstrong J, Huang Y-C, Elkeeb L, Ortiz A, Harris R et al (2012) Enhanced port-wine stain lightening achieved with combined treatment of selective photothermolysis and imiquimod. J Am Acad Dermatol 66(4):634–641PubMedPubMedCentralCrossRef Tremaine AM, Armstrong J, Huang Y-C, Elkeeb L, Ortiz A, Harris R et al (2012) Enhanced port-wine stain lightening achieved with combined treatment of selective photothermolysis and imiquimod. J Am Acad Dermatol 66(4):634–641PubMedPubMedCentralCrossRef
26.
Zurück zum Zitat Gao L, Qian L, Wang L, Li K, Yin R, Wang Y et al (2018) Topical Halometasone Reduces Acute Adverse Effects Induced by Pulsed Dye Laser for Treatment of Port Wine Stain Birthmarks. J Lasers Med Sci 9(1):19–22PubMedCrossRef Gao L, Qian L, Wang L, Li K, Yin R, Wang Y et al (2018) Topical Halometasone Reduces Acute Adverse Effects Induced by Pulsed Dye Laser for Treatment of Port Wine Stain Birthmarks. J Lasers Med Sci 9(1):19–22PubMedCrossRef
27.
Zurück zum Zitat Chapas AM, Eickhorst K, Geronemus RG (2007) Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Lasers Surg Med 39(7):563–568PubMedCrossRef Chapas AM, Eickhorst K, Geronemus RG (2007) Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Lasers Surg Med 39(7):563–568PubMedCrossRef
28.
Zurück zum Zitat Sadeghinia A, Moghaddas S, Tavakolpour S, Teimourpour A, Danespazhooh M, Mahmoudi H (2019) Treatment of port wine stains with 595-nm pulsed dye laser in 27 pediatric patients: A prospective study in the Iranian population. J Cosmet Laser Ther 21(7-8):373–377PubMedCrossRef Sadeghinia A, Moghaddas S, Tavakolpour S, Teimourpour A, Danespazhooh M, Mahmoudi H (2019) Treatment of port wine stains with 595-nm pulsed dye laser in 27 pediatric patients: A prospective study in the Iranian population. J Cosmet Laser Ther 21(7-8):373–377PubMedCrossRef
29.
Zurück zum Zitat Liu H, Dang Y, Chai X, Wang Z, Ma L, Ren Q (2007) Treatment of port-wine stains with the 595-nm pulsed dye laser: a pilot study in Chinese patients. Clin Exp Dermatol 32(6):646–649PubMedCrossRef Liu H, Dang Y, Chai X, Wang Z, Ma L, Ren Q (2007) Treatment of port-wine stains with the 595-nm pulsed dye laser: a pilot study in Chinese patients. Clin Exp Dermatol 32(6):646–649PubMedCrossRef
30.
Zurück zum Zitat Tomson N, Lim SPR, Abdullah A, Lanigan SW (2006) The treatment of port-wine stains with the pulsed-dye laser at 2-week and 6-week intervals: a comparative study. Br J Dermatol 154(4):676–679PubMedCrossRef Tomson N, Lim SPR, Abdullah A, Lanigan SW (2006) The treatment of port-wine stains with the pulsed-dye laser at 2-week and 6-week intervals: a comparative study. Br J Dermatol 154(4):676–679PubMedCrossRef
31.
Zurück zum Zitat Woo S-H, Ahn H-H, Kim S-N, Kye Y-C (2006) Treatment of vascular skin lesions with the variable-pulse 595 nm pulsed dye laser. Dermatol Surg 32(1):41–48PubMedCrossRef Woo S-H, Ahn H-H, Kim S-N, Kye Y-C (2006) Treatment of vascular skin lesions with the variable-pulse 595 nm pulsed dye laser. Dermatol Surg 32(1):41–48PubMedCrossRef
32.
Zurück zum Zitat Abdul Latif AA, Abdel-Hameed AKS, Salama OAAM (2019) Immediate post-irradiation dermoscopic vascular changes versus purpura as a therapeutic endpoint in pulsed-dye laser treatment of port wine stains. Dermatol Ther 32(6):e13094PubMedCrossRef Abdul Latif AA, Abdel-Hameed AKS, Salama OAAM (2019) Immediate post-irradiation dermoscopic vascular changes versus purpura as a therapeutic endpoint in pulsed-dye laser treatment of port wine stains. Dermatol Ther 32(6):e13094PubMedCrossRef
33.
Zurück zum Zitat Li L, Kono T, Groff WF, Chan HH, Kitazawa Y, Nozaki M (2008) Comparison study of a long-pulse pulsed dye laser and a long-pulse pulsed alexandrite laser in the treatment of port wine stains. J Cosmet Laser Ther 10(1):12–15PubMedCrossRef Li L, Kono T, Groff WF, Chan HH, Kitazawa Y, Nozaki M (2008) Comparison study of a long-pulse pulsed dye laser and a long-pulse pulsed alexandrite laser in the treatment of port wine stains. J Cosmet Laser Ther 10(1):12–15PubMedCrossRef
34.
Zurück zum Zitat Yang MU, Yaroslavsky AN, Farinelli WA, Flotte TJ, Rius-Diaz F, Tsao SS et al (2005) Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains. J Am Acad Dermatol 52(3 Pt 1):480–490PubMedCrossRef Yang MU, Yaroslavsky AN, Farinelli WA, Flotte TJ, Rius-Diaz F, Tsao SS et al (2005) Long-pulsed neodymium:yttrium-aluminum-garnet laser treatment for port-wine stains. J Am Acad Dermatol 52(3 Pt 1):480–490PubMedCrossRef
35.
Zurück zum Zitat Zhu J, Yu W, Ma G, Lin X (2021) Blood Perfusion May Determine the Therapeutic Effect of Pulsed Dye Laser on Port-Wine Stains Located on Extremities. Photobiomodul Photomed Laser Surg 39(7):486–491PubMed Zhu J, Yu W, Ma G, Lin X (2021) Blood Perfusion May Determine the Therapeutic Effect of Pulsed Dye Laser on Port-Wine Stains Located on Extremities. Photobiomodul Photomed Laser Surg 39(7):486–491PubMed
36.
Zurück zum Zitat Yu W, Cen Q, Chen Y, Zhu J, Lin X (2021) Combination Therapy of Pulsed Dye Laser With Intense Pulsed Light in Port-Wine Stain Treatment: A Prospective Side-by-Side Comparison. Dermatol Surg 47(9):1229–1232PubMedCrossRef Yu W, Cen Q, Chen Y, Zhu J, Lin X (2021) Combination Therapy of Pulsed Dye Laser With Intense Pulsed Light in Port-Wine Stain Treatment: A Prospective Side-by-Side Comparison. Dermatol Surg 47(9):1229–1232PubMedCrossRef
37.
Zurück zum Zitat Sodha P, Richmond H, Friedman PM (2021) Safe and Effective Use of a Novel Large Spot Size 595-nm Pulsed Dye Laser With High Energies for Rapid Improvement of Adult and Pediatric Port-Wine Birthmarks. Dermatol Surg 47(8):1147–1149PubMedCrossRef Sodha P, Richmond H, Friedman PM (2021) Safe and Effective Use of a Novel Large Spot Size 595-nm Pulsed Dye Laser With High Energies for Rapid Improvement of Adult and Pediatric Port-Wine Birthmarks. Dermatol Surg 47(8):1147–1149PubMedCrossRef
38.
Zurück zum Zitat Thajudheen CP, Jyothy K, Priyadarshini A (2014) Treatment of port-wine stains with flash lamp pumped pulsed dye laser on Indian skin: a six year study. J Cutan Aesthet Surg 7(1):32–36PubMedPubMedCentralCrossRef Thajudheen CP, Jyothy K, Priyadarshini A (2014) Treatment of port-wine stains with flash lamp pumped pulsed dye laser on Indian skin: a six year study. J Cutan Aesthet Surg 7(1):32–36PubMedPubMedCentralCrossRef
39.
Zurück zum Zitat Liu X, Fan Y, Huang J, Zeng R, Cao G, Chen M et al (2015) Can we predict the outcome of 595-nm wavelength pulsed dye laser therapy on capillary vascular malformations from the first beginning: a pilot study of efficacy co-related factors in 686 Chinese patients. Lasers Med Sci 30(3):1041–1046PubMedCrossRef Liu X, Fan Y, Huang J, Zeng R, Cao G, Chen M et al (2015) Can we predict the outcome of 595-nm wavelength pulsed dye laser therapy on capillary vascular malformations from the first beginning: a pilot study of efficacy co-related factors in 686 Chinese patients. Lasers Med Sci 30(3):1041–1046PubMedCrossRef
40.
Zurück zum Zitat Yu W, Chen Y, Cen Q, Zhu J, Lin X (2022) Can 595-nm Pulsed Dye Laser in Conjunction With an Optical Clearing Agent Improve the Treatment of Port-Wine Stains? Dermatol Surg 48(5):534–538PubMedCrossRef Yu W, Chen Y, Cen Q, Zhu J, Lin X (2022) Can 595-nm Pulsed Dye Laser in Conjunction With an Optical Clearing Agent Improve the Treatment of Port-Wine Stains? Dermatol Surg 48(5):534–538PubMedCrossRef
41.
Zurück zum Zitat Noormohammadpour P, Ehsani AH, Mahmoudi H, Balighi K, Razavi Z (2021) Does Double-Pass Pulsed-Dye Laser With Long and Short Pulse Duration Increase Treatment Efficacy of Port-Wine Stain? A Randomized Clinical Trial. Dermatol Surg 47(4):e122–e1e6PubMedCrossRef Noormohammadpour P, Ehsani AH, Mahmoudi H, Balighi K, Razavi Z (2021) Does Double-Pass Pulsed-Dye Laser With Long and Short Pulse Duration Increase Treatment Efficacy of Port-Wine Stain? A Randomized Clinical Trial. Dermatol Surg 47(4):e122–e1e6PubMedCrossRef
42.
Zurück zum Zitat Yu W, Zhu J, Wang L, Qiu Y, Chen Y, Yang X et al (2018) Double Pass 595 nm Pulsed Dye Laser Does Not Enhance the Efficacy of Port Wine Stains Compared with Single Pass: A Randomized Comparison with Histological Examination. Photomed Laser Surg 36(6):305–312PubMedCrossRef Yu W, Zhu J, Wang L, Qiu Y, Chen Y, Yang X et al (2018) Double Pass 595 nm Pulsed Dye Laser Does Not Enhance the Efficacy of Port Wine Stains Compared with Single Pass: A Randomized Comparison with Histological Examination. Photomed Laser Surg 36(6):305–312PubMedCrossRef
43.
Zurück zum Zitat Fiskerstrand EJ, Svaasand LO, Volden G (1998) Pigmentary changes after pulsed dye laser treatment in 125 northern European patients with port wine stains. Br J Dermatol 138(3):477–479PubMedCrossRef Fiskerstrand EJ, Svaasand LO, Volden G (1998) Pigmentary changes after pulsed dye laser treatment in 125 northern European patients with port wine stains. Br J Dermatol 138(3):477–479PubMedCrossRef
44.
Zurück zum Zitat Boixeda P, Núñez M, Pérez B, de las Heras ME, Hilara Y, Ledo A (1997) Complications of 585-nm pulsed dye laser therapy. Int J Dermatol 36(5):393–397PubMedCrossRef Boixeda P, Núñez M, Pérez B, de las Heras ME, Hilara Y, Ledo A (1997) Complications of 585-nm pulsed dye laser therapy. Int J Dermatol 36(5):393–397PubMedCrossRef
45.
Zurück zum Zitat Seukeran DC, Collins P, Sheehan-Dare RA (1997) Adverse reactions following pulsed tunable dye laser treatment of port wine stains in 701 patients. Br J Dermatol 136(5):725–729PubMedCrossRef Seukeran DC, Collins P, Sheehan-Dare RA (1997) Adverse reactions following pulsed tunable dye laser treatment of port wine stains in 701 patients. Br J Dermatol 136(5):725–729PubMedCrossRef
46.
Zurück zum Zitat Lorenz S, Scherer K, Wimmershoff MB, Landthaler M, Hohenleutner U (2003) Variable pulse frequency-doubled Nd:YAG laser versus flashlamp-pumped pulsed dye laser in the treatment of port wine stains. Acta Derm Venereol 83(3):210–213PubMedCrossRef Lorenz S, Scherer K, Wimmershoff MB, Landthaler M, Hohenleutner U (2003) Variable pulse frequency-doubled Nd:YAG laser versus flashlamp-pumped pulsed dye laser in the treatment of port wine stains. Acta Derm Venereol 83(3):210–213PubMedCrossRef
47.
Zurück zum Zitat Gao K, Huang Z, Yuan KH, Zhang B, Hu ZQ (2013) Side-by-side comparison of photodynamic therapy and pulsed-dye laser treatment of port-wine stain birthmarks. Br J Dermatol 168(5):1040–1046PubMedCrossRef Gao K, Huang Z, Yuan KH, Zhang B, Hu ZQ (2013) Side-by-side comparison of photodynamic therapy and pulsed-dye laser treatment of port-wine stain birthmarks. Br J Dermatol 168(5):1040–1046PubMedCrossRef
48.
Zurück zum Zitat Yuan K-H, Li Q, Yu W-L, Zeng D, Zhang C, Huang Z (2008) Comparison of photodynamic therapy and pulsed dye laser in patients with port wine stain birthmarks: a retrospective analysis. Photodiagn Photodyn Ther 5(1):50–57CrossRef Yuan K-H, Li Q, Yu W-L, Zeng D, Zhang C, Huang Z (2008) Comparison of photodynamic therapy and pulsed dye laser in patients with port wine stain birthmarks: a retrospective analysis. Photodiagn Photodyn Ther 5(1):50–57CrossRef
49.
Zurück zum Zitat Chang CJ, Nelson JS (1999) Cryogen spray cooling and higher fluence pulsed dye laser treatment improve port-wine stain clearance while minimizing epidermal damage. Dermatol Surg 25(10):767–772PubMedCrossRef Chang CJ, Nelson JS (1999) Cryogen spray cooling and higher fluence pulsed dye laser treatment improve port-wine stain clearance while minimizing epidermal damage. Dermatol Surg 25(10):767–772PubMedCrossRef
50.
Zurück zum Zitat Ho WS, Chan HH, Ying SY, Chan PC (2002) Laser treatment of congenital facial port-wine stains: long-term efficacy and complication in Chinese patients. Lasers Surg Med 30(1):44–47PubMedCrossRef Ho WS, Chan HH, Ying SY, Chan PC (2002) Laser treatment of congenital facial port-wine stains: long-term efficacy and complication in Chinese patients. Lasers Surg Med 30(1):44–47PubMedCrossRef
51.
Zurück zum Zitat Hammes S, Roos S, Raulin C, Ockenfels HM, Greve B (2007) Does dye laser treatment with higher fluences in combination with cold air cooling improve the results of port-wine stains? J Eur Acad Dermatol Venereol 21(9):1229–1233PubMedCrossRef Hammes S, Roos S, Raulin C, Ockenfels HM, Greve B (2007) Does dye laser treatment with higher fluences in combination with cold air cooling improve the results of port-wine stains? J Eur Acad Dermatol Venereol 21(9):1229–1233PubMedCrossRef
52.
Zurück zum Zitat Greve B, Hammes S, Raulin C (2001) The effect of cold air cooling on 585 nm pulsed dye laser treatment of port-wine stains. Dermatol Surg 27(7):633–636PubMed Greve B, Hammes S, Raulin C (2001) The effect of cold air cooling on 585 nm pulsed dye laser treatment of port-wine stains. Dermatol Surg 27(7):633–636PubMed
53.
Zurück zum Zitat Zhang B, Zhang T-H, Huang Z, Li Q, Yuan K-H, Hu Z-Q (2014) Comparison of pulsed dye laser (PDL) and photodynamic therapy (PDT) for treatment of facial port-wine stain (PWS) birthmarks in pediatric patients. Photodiagn Photodyn Ther 11(4):491–497CrossRef Zhang B, Zhang T-H, Huang Z, Li Q, Yuan K-H, Hu Z-Q (2014) Comparison of pulsed dye laser (PDL) and photodynamic therapy (PDT) for treatment of facial port-wine stain (PWS) birthmarks in pediatric patients. Photodiagn Photodyn Ther 11(4):491–497CrossRef
54.
Zurück zum Zitat Wareham WJ, Cole RP, Royston SL, Wright PA (2009) Adverse effects reported in pulsed dye laser treatment for port wine stains. Lasers Med Sci 24(2):241–246PubMedCrossRef Wareham WJ, Cole RP, Royston SL, Wright PA (2009) Adverse effects reported in pulsed dye laser treatment for port wine stains. Lasers Med Sci 24(2):241–246PubMedCrossRef
55.
Zurück zum Zitat Sommer S, Seukeran DC, Sheehan-Dare RA (2003) Efficacy of pulsed dye laser treatment of port wine stain malformations of the lower limb. Br J Dermatol 149(4):770–775PubMedCrossRef Sommer S, Seukeran DC, Sheehan-Dare RA (2003) Efficacy of pulsed dye laser treatment of port wine stain malformations of the lower limb. Br J Dermatol 149(4):770–775PubMedCrossRef
56.
Zurück zum Zitat Taïeb A, Touati L, Cony M, Léauté-Labrèze C, Mortureux P, Renaud P et al (1994) Treatment of port-wine stains with the 585-nm flashlamp-pulsed tunable dye laser: a study of 74 patients. Dermatology 188(4):276–281PubMedCrossRef Taïeb A, Touati L, Cony M, Léauté-Labrèze C, Mortureux P, Renaud P et al (1994) Treatment of port-wine stains with the 585-nm flashlamp-pulsed tunable dye laser: a study of 74 patients. Dermatology 188(4):276–281PubMedCrossRef
57.
Zurück zum Zitat Goldman MP, Fitzpatrick RE, Ruiz-Esparza J (1993) Treatment of port-wine stains (capillary malformation) with the flashlamp-pumped pulsed dye laser. J Pediatr 122(1):71–77PubMedCrossRef Goldman MP, Fitzpatrick RE, Ruiz-Esparza J (1993) Treatment of port-wine stains (capillary malformation) with the flashlamp-pumped pulsed dye laser. J Pediatr 122(1):71–77PubMedCrossRef
58.
Zurück zum Zitat Alster TS, Wilson F (1994) Treatment of port-wine stains with the flashlamp-pumped pulsed dye laser: extended clinical experience in children and adults. Ann Plast Surg 32(5):478–484PubMedCrossRef Alster TS, Wilson F (1994) Treatment of port-wine stains with the flashlamp-pumped pulsed dye laser: extended clinical experience in children and adults. Ann Plast Surg 32(5):478–484PubMedCrossRef
59.
Zurück zum Zitat Chang C-J, Hsiao Y-C, Mihm MC, Nelson JS (2008) Pilot study examining the combined use of pulsed dye laser and topical Imiquimod versus laser alone for treatment of port wine stain birthmarks. Lasers Surg Med 40(9):605–610PubMedPubMedCentralCrossRef Chang C-J, Hsiao Y-C, Mihm MC, Nelson JS (2008) Pilot study examining the combined use of pulsed dye laser and topical Imiquimod versus laser alone for treatment of port wine stain birthmarks. Lasers Surg Med 40(9):605–610PubMedPubMedCentralCrossRef
60.
Zurück zum Zitat Bernstein EF, Brown DB (2005) Efficacy of the 1.5 millisecond pulse-duration, 585 nm, pulsed-dye laser for treating port-wine stains. Lasers Surg Med 36(5):341–346PubMedCrossRef Bernstein EF, Brown DB (2005) Efficacy of the 1.5 millisecond pulse-duration, 585 nm, pulsed-dye laser for treating port-wine stains. Lasers Surg Med 36(5):341–346PubMedCrossRef
61.
Zurück zum Zitat Chiu C-H, Chan HH-L, Ho W-S, Yeung C-K, Nelson JS (2003) Prospective study of pulsed dye laser in conjunction with cryogen spray cooling for treatment of port wine stains in Chinese patients. Dermatol Surg 29(9):909–915PubMed Chiu C-H, Chan HH-L, Ho W-S, Yeung C-K, Nelson JS (2003) Prospective study of pulsed dye laser in conjunction with cryogen spray cooling for treatment of port wine stains in Chinese patients. Dermatol Surg 29(9):909–915PubMed
62.
Zurück zum Zitat Chang C-J, Yu D-Y, Chang S-Y, Hsiao Y-C, Ting K, Chen K-T et al (2015) Real-time photothermal imaging and response in pulsed dye laser treatment for port wine stain patients. Biom J 38(4):342–349 Chang C-J, Yu D-Y, Chang S-Y, Hsiao Y-C, Ting K, Chen K-T et al (2015) Real-time photothermal imaging and response in pulsed dye laser treatment for port wine stain patients. Biom J 38(4):342–349
63.
Zurück zum Zitat Tan E, Vinciullo C (1996) Pulsed dye laser treatment of port-wine stains: a review of patients treated in Western Australia. Med J Aust 164(6):333–336PubMedCrossRef Tan E, Vinciullo C (1996) Pulsed dye laser treatment of port-wine stains: a review of patients treated in Western Australia. Med J Aust 164(6):333–336PubMedCrossRef
64.
Zurück zum Zitat van der Horst CM, Koster PH, de Borgie CA, Bossuyt PM, van Gemert MJ (1998) Effect of the timing of treatment of port-wine stains with the flash-lamp-pumped pulsed-dye laser. N Engl J Med 338(15):1028–1033PubMedCrossRef van der Horst CM, Koster PH, de Borgie CA, Bossuyt PM, van Gemert MJ (1998) Effect of the timing of treatment of port-wine stains with the flash-lamp-pumped pulsed-dye laser. N Engl J Med 338(15):1028–1033PubMedCrossRef
65.
Zurück zum Zitat Sommer S, Sheehan-Dare RA (2000) Pulsed dye laser treatment of port-wine stains in pigmented skin. J Am Acad Dermatol 42(4):667–671PubMedCrossRef Sommer S, Sheehan-Dare RA (2000) Pulsed dye laser treatment of port-wine stains in pigmented skin. J Am Acad Dermatol 42(4):667–671PubMedCrossRef
66.
Zurück zum Zitat Ashinoff R, Geronemus RG (1990) Effect of the topical anesthetic EMLA on the efficacy of pulsed dye laser treatment of port-wine stains. J Dermatol Surg Oncol 16(11):1008–1011PubMedCrossRef Ashinoff R, Geronemus RG (1990) Effect of the topical anesthetic EMLA on the efficacy of pulsed dye laser treatment of port-wine stains. J Dermatol Surg Oncol 16(11):1008–1011PubMedCrossRef
67.
Zurück zum Zitat Sharma VK, Khandpur S (2007) Efficacy of pulsed dye laser in facial port-wine stains in Indian patients. Dermatol Surg 33(5):560–566PubMed Sharma VK, Khandpur S (2007) Efficacy of pulsed dye laser in facial port-wine stains in Indian patients. Dermatol Surg 33(5):560–566PubMed
68.
Zurück zum Zitat Goh CL (2000) Flashlamp-pumped pulsed dye laser (585nm) for the treatment of portwine stains--a study of treatment outcome in 94 Asian patients in Singapore. Singap Med J 41(1):24–28 Goh CL (2000) Flashlamp-pumped pulsed dye laser (585nm) for the treatment of portwine stains--a study of treatment outcome in 94 Asian patients in Singapore. Singap Med J 41(1):24–28
69.
Zurück zum Zitat Wlotzke U, Hohenleutner U, Abd-El-Raheem TA, Bäumler W, Landthaler M (1996) Side-effects and complications of flashlamp-pumped pulsed dye laser therapy of port-wine stains. A prospective study. Br J Dermatol 134(3):475–480PubMedCrossRef Wlotzke U, Hohenleutner U, Abd-El-Raheem TA, Bäumler W, Landthaler M (1996) Side-effects and complications of flashlamp-pumped pulsed dye laser therapy of port-wine stains. A prospective study. Br J Dermatol 134(3):475–480PubMedCrossRef
70.
Zurück zum Zitat Reyes BA, Geronemus R (1990) Treatment of port-wine stains during childhood with the flashlamp-pumped pulsed dye laser. J Am Acad Dermatol 23(6 Pt 1):1142–1148PubMedCrossRef Reyes BA, Geronemus R (1990) Treatment of port-wine stains during childhood with the flashlamp-pumped pulsed dye laser. J Am Acad Dermatol 23(6 Pt 1):1142–1148PubMedCrossRef
71.
Zurück zum Zitat Greve B, Raulin C (2004) Prospective study of port wine stain treatment with dye laser: comparison of two wavelengths (585 nm vs. 595 nm) and two pulse durations (0.5 milliseconds vs. 20 milliseconds). Lasers Surg Med 34(2):168–173PubMedCrossRef Greve B, Raulin C (2004) Prospective study of port wine stain treatment with dye laser: comparison of two wavelengths (585 nm vs. 595 nm) and two pulse durations (0.5 milliseconds vs. 20 milliseconds). Lasers Surg Med 34(2):168–173PubMedCrossRef
72.
Zurück zum Zitat Kelly KM, Nanda VS, Nelson JS (2002) Treatment of port-wine stain birthmarks using the 1.5-msec pulsed dye laser at high fluences in conjunction with cryogen spray cooling. Dermatol Surg 28(4):309–313PubMed Kelly KM, Nanda VS, Nelson JS (2002) Treatment of port-wine stain birthmarks using the 1.5-msec pulsed dye laser at high fluences in conjunction with cryogen spray cooling. Dermatol Surg 28(4):309–313PubMed
73.
Zurück zum Zitat Chang C-J, Kelly KM, Van Gemert MJC, Nelson JS (2002) Comparing the effectiveness of 585-nm vs 595-nm wavelength pulsed dye laser treatment of port wine stains in conjunction with cryogen spray cooling. Lasers Surg Med 31(5):352–358PubMedCrossRef Chang C-J, Kelly KM, Van Gemert MJC, Nelson JS (2002) Comparing the effectiveness of 585-nm vs 595-nm wavelength pulsed dye laser treatment of port wine stains in conjunction with cryogen spray cooling. Lasers Surg Med 31(5):352–358PubMedCrossRef
74.
Zurück zum Zitat Liu S, Yang C, Xu S, Yuan C, Yang S, Zhang X (2010) Pyogenic granuloma arising as a complication of 595 nm tunable pulsed dye laser treatment of port-wine stains: report of four cases. Dermatol Surg 36(8):1341–1343PubMedCrossRef Liu S, Yang C, Xu S, Yuan C, Yang S, Zhang X (2010) Pyogenic granuloma arising as a complication of 595 nm tunable pulsed dye laser treatment of port-wine stains: report of four cases. Dermatol Surg 36(8):1341–1343PubMedCrossRef
75.
Zurück zum Zitat Chen T, Frieden IJ (2007) Development of extensive flat warts after pulsed dye laser treatment of a port-wine stain. Dermatol Surg 33(6):734–735PubMed Chen T, Frieden IJ (2007) Development of extensive flat warts after pulsed dye laser treatment of a port-wine stain. Dermatol Surg 33(6):734–735PubMed
76.
Zurück zum Zitat Eckembrecher FJ, Eckembrecher DG, Camacho I, Shah H, Jaalouk D, Nouri K (2023) A review of treatment of port-wine stains with pulsed dye laser in fitzpatrick skin type IV-VI. Arch Dermatol Res 315(9):2505–2511PubMedCrossRef Eckembrecher FJ, Eckembrecher DG, Camacho I, Shah H, Jaalouk D, Nouri K (2023) A review of treatment of port-wine stains with pulsed dye laser in fitzpatrick skin type IV-VI. Arch Dermatol Res 315(9):2505–2511PubMedCrossRef
77.
Zurück zum Zitat Nautiyal A, Wairkar S (2021) Management of hyperpigmentation: Current treatments and emerging therapies. Pigment Cell Melanoma Res 34(6):1000–1014PubMedCrossRef Nautiyal A, Wairkar S (2021) Management of hyperpigmentation: Current treatments and emerging therapies. Pigment Cell Melanoma Res 34(6):1000–1014PubMedCrossRef
78.
Zurück zum Zitat Sowash M, Alster T (2023) Review of Laser Treatments for Post-Inflammatory Hyperpigmentation in Skin of Color. Am J Clin Dermatol 24(3):381–396PubMedCrossRef Sowash M, Alster T (2023) Review of Laser Treatments for Post-Inflammatory Hyperpigmentation in Skin of Color. Am J Clin Dermatol 24(3):381–396PubMedCrossRef
79.
Zurück zum Zitat Shah S, Alster TS (2010) Laser treatment of dark skin: an updated review. Am J Clin Dermatol 11(6):389–397PubMedCrossRef Shah S, Alster TS (2010) Laser treatment of dark skin: an updated review. Am J Clin Dermatol 11(6):389–397PubMedCrossRef
Metadaten
Titel
Complication rates and safety of pulsed dye laser treatment for port-wine stain: a systematic review and meta-analysis
verfasst von
Meng dong Shi
Kun Yang
Shu bo Li
Qian Zhao
Ran Huo
Cong Fu
Publikationsdatum
01.12.2024
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 1/2024
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-023-03961-5

Weitere Artikel der Ausgabe 1/2024

Lasers in Medical Science 1/2024 Zur Ausgabe