Erschienen in:
14.07.2022 | Original Article
Diagnostic Conflict in Occult Breast Cancers and Clinical Results of a Tertiary Center: A Cross-sectional Study
verfasst von:
Fatih Dal, Hasan Ökmen, Kıvılcım Ulusan, Semiha Battal Havare, Özlem Mermut, Mehmet Ali Nazlı, Serkan Sarı
Erschienen in:
Indian Journal of Surgery
|
Ausgabe 3/2023
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Abstract
Our aim is to present the results of early-stage clinicopathological occult breast cancer cases in a tertiary centre for breast diseases. There were 17 cases (T0/TxN 1,2,3 M0/M1) that were classified as clinicoradiological occult breast cancer (crOBC) from 01 January 2006 to 01 January 2018. By re-evaluating the postoperative histopathological and immunohistochemical results, the patients were divided into three groups; early-stage clinicopathological occult breast cancer [ecpOBC (T0/TxN1,2,3M0)], metastatic clinicopathological occult breast cancer [(mcpOBC (T0/TXN + M1)], and non-occult breast cancer (nOBC). Patients with ecpOBC (n = 11) were included in the study. The frequency of operable ecpOBC was 0.46% (11/2342) and the frequency of non-operable mcpOBC was 0.08% (2/2342). While modified radical mastectomy (MRM) was performed on 27.3 (3/11) of the patients, 72.7% (8/11) had axillary lymph node dissection (ALND). The operated MRM and ALND groups were followed up for at least 3 years after receiving chemotherapy (CTX) and radiotherapy (RT). The 3-year disease-free survival (DFS) rates of the groups were respectively 100% and 87.5%, and there was no significant difference between the groups regarding DFS (p = 0.540). Considering the concern for cosmesis in ecpOBC patients, ALND seems to be as an appropriate surgical approach.