Ausgabe 1/2021
Inhalt (60 Artikel)
Disparate volumetric fluid shifts across cerebral tissue compartments with two different anesthetics
Burhan O. Ozturk, Brittany Monte, Sunil Koundal, Feng Dai, Helene Benveniste, Hedok Lee
Structural disruption of the blood–brain barrier in repetitive primary blast injury
Gozde Uzunalli, Seth Herr, Alexandra M. Dieterly, Riyi Shi, L. Tiffany Lyle
Presence of a mutation in PSEN1 or PSEN2 gene is associated with an impaired brain endothelial cell phenotype in vitro
Snehal Raut, Ronak Patel, Abraham J. Al-Ahmad
Cerebrospinal fluid biomarkers of neuroinflammation in children with hydrocephalus and shunt malfunction
Carolyn A. Harris, Diego M. Morales, Rooshan Arshad, James P. McAllister II, David D. Limbrick Jr
The relationship between cerebral blood flow and venous sinus pressure: can hyperemia induce idiopathic intracranial hypertension?
Alexander Robert Bateman, Grant Alexander Bateman, Tracie Barber
Transfer of rhodamine-123 into the brain and cerebrospinal fluid of fetal, neonatal and adult rats
Liam M. Koehn, Katarzyna M. Dziegielewska, Mark D. Habgood, Yifan Huang, Norman R. Saunders
Circulating tight-junction proteins are potential biomarkers for blood–brain barrier function in a model of neonatal hypoxic/ischemic brain injury
E. Axel Andersson, Carina Mallard, C. Joakim Ek
Quantification of arterial, venous, and cerebrospinal fluid flow dynamics by magnetic resonance imaging under simulated micro-gravity conditions: a prospective cohort study
Arslan M. Zahid, Bryn Martin, Stephanie Collins, John N. Oshinski, C. Ross Ethier
Are CSF CXCL13 concentrations solely dependent on intrathecal production? A commentary on “Chemokine CXCL13 in serum, CSF, and blood–CSF barrier function”
Krista D. DiSano, Francesca Gilli, Andrew R. Pachner
Protecting P-glycoprotein at the blood–brain barrier from degradation in an Alzheimer’s disease mouse model
Yujie Ding, Yu Zhong, Andrea Baldeshwiler, Erin L. Abner, Björn Bauer, Anika M. S. Hartz
Variations in the cerebrospinal fluid dynamics of the American alligator (Alligator mississippiensis)
Bruce A. Young, James Adams, Jonathan M. Beary, Kent-Andre Mardal, Robert Schneider, Tatyana Kondrashova
In vitro evaluation of cerebrospinal fluid velocity measurement in type I Chiari malformation: repeatability, reproducibility, and agreement using 2D phase contrast and 4D flow MRI
Gwendolyn Williams, Suraj Thyagaraj, Audrey Fu, John Oshinski, Daniel Giese, Alexander C. Bunck, Eleonora Fornari, Francesco Santini, Mark Luciano, Francis Loth, Bryn A. Martin
Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro
Julia Baumann, Chih-Chieh Tsao, Sheng-Fu Huang, Max Gassmann, Omolara O. Ogunshola
Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas
Francesco Girolamo, Ignazio de Trizio, Mariella Errede, Giovanna Longo, Antonio d’Amati, Daniela Virgintino
Microglia activated by microbial neuraminidase contributes to ependymal cell death
María del Mar Fernández-Arjona, Ana León-Rodríguez, María Dolores López-Ávalos, Jesús M. Grondona
Direction and magnitude of cerebrospinal fluid flow vary substantially across central nervous system diseases
Per Kristian Eide, Lars Magnus Valnes, Erika Kristina Lindstrøm, Kent-Andre Mardal, Geir Ringstad
Epigenetics in blood–brain barrier disruption
Stephanie A. Ihezie, Iny Elizebeth Mathew, Devin W. McBride, Ari Dienel, Spiros L. Blackburn, Peeyush Kumar Thankamani Pandit
Evaluating the cerebrospinal fluid tap test with the Hellström iNPH scale for patients with idiopathic normal pressure hydrocephalus
Johanna Rydja, Andreas Eleftheriou, Fredrik Lundin
Reference values for intracranial pressure and lumbar cerebrospinal fluid pressure: a systematic review
Nicolas Hernandez Norager, Markus Harboe Olsen, Sarah Hornshoej Pedersen, Casper Schwartz Riedel, Marek Czosnyka, Marianne Juhler
Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia
Shigeki Yamada, Masatsune Ishikawa, Kazuhiko Nozaki
Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion
Zhengyu Sun, Chenhao Gao, Dandan Gao, Ruihua Sun, Wei Li, Fengyu Wang, Yanliang Wang, Huixia Cao, Guoyu Zhou, Jiewen Zhang, Junkui Shang
Serial Tap Test of patients with idiopathic normal pressure hydrocephalus: impact on cognitive function and its meaning
Samanta Fabrício Blattes da Rocha, Pedro André Kowacs, Ricardo Krause Martinez de Souza, Matheus Kahakura Franco Pedro, Ricardo Ramina, Hélio A. Ghizoni Teive
Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus
Karolina Minta, Anna Jeppsson, Gunnar Brinkmalm, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Mats Tullberg, Ulf Andreasson
Brain Barriers and brain fluids research in 2020 and the fluids and barriers of the CNS thematic series on advances in in vitro modeling of the blood–brain barrier and neurovascular unit
Richard F. Keep, Hazel C. Jones, Lester R. Drewes
Intracranial pressure waveform characteristics in idiopathic normal pressure hydrocephalus and late-onset idiopathic aqueductal stenosis
Lauren M. Green, Thomas Wallis, Martin U. Schuhmann, Matthias Jaeger
Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size
Rebecca Faresjö, Gillian Bonvicini, Xiaotian T. Fang, Ximena Aguilar, Dag Sehlin, Stina Syvänen
Brain endothelial LRP1 maintains blood–brain barrier integrity
Steffen E. Storck, Magdalena Kurtyka, Claus U. Pietrzik
Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers
Hossam Kadry, Behnam Noorani, Ulrich Bickel, Thomas J. Abbruscato, Luca Cucullo
Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging
Xinfeng Yu, Xinzhen Yin, Hui Hong, Shuyue Wang, Yeerfan Jiaerken, Fan Zhang, Ofer Pasternak, Ruiting Zhang, Linglin Yang, Min Lou, Minming Zhang, Peiyu Huang
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus
Betsaida Ojeda-Pérez, José A. Campos-Sandoval, María García-Bonilla, Casimiro Cárdenas-García, Patricia Páez-González, Antonio J. Jiménez
The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Vijay Kumar, Zobia Umair, Shiv Kumar, Ravi Shankar Goutam, Soochul Park, Jaebong Kim
SARS-CoV-2: is there neuroinvasion?
Conor McQuaid, Molly Brady, Rashid Deane
A multicenter retrospective study of heterogeneous tissue aggregates obstructing ventricular catheters explanted from patients with hydrocephalus
Prashant Hariharan, Jeffrey Sondheimer, Alexandra Petroj, Jacob Gluski, Andrew Jea, William E. Whitehead, Sandeep Sood, Steven D. Ham, Brandon G. Rocque, Neena I. Marupudi, James P. McAllister II, David Limbrick, Marc R. Del Bigio, Carolyn A. Harris
Characterization of the blood–brain barrier in genetically diverse laboratory mouse strains
Johanna Schaffenrath, Sheng-Fu Huang, Tania Wyss, Mauro Delorenzi, Annika Keller
Imaging features associated with idiopathic normal pressure hydrocephalus have high specificity even when comparing with vascular dementia and atypical parkinsonism
David Fällmar, Oliver Andersson, Lena Kilander, Malin Löwenmark, Dag Nyholm, Johan Virhammar
Similarities and differences in the localization, trafficking, and function of P-glycoprotein in MDR1-EGFP-transduced rat versus human brain capillary endothelial cell lines
Birthe Gericke, Saskia Borsdorf, Inka Wienböker, Andreas Noack, Sandra Noack, Wolfgang Löscher
Incidental findings of typical iNPH imaging signs in asymptomatic subjects with subclinical cognitive decline
Doortje C. Engel, Lukas Pirpamer, Edith Hofer, Reinhold Schmidt, Cornelia Brendle
Impact of sex differences on thrombin-induced hydrocephalus and white matter injury: the role of neutrophils
Kang Peng, Sravanthi Koduri, Fan Xia, Feng Gao, Ya Hua, Richard F. Keep, Guohua Xi
Role of hemagglutinin esterase protein in neurological manifestation of COVID-19
Milad Zandi, Hassan Karami, Saber Soltani
The CXCL13/CXCR5-chemokine axis in neuroinflammation: evidence of CXCR5+CD4 T cell recruitment to CSF
Christine Harrer, Ferdinand Otto, Georg Pilz, Elisabeth Haschke-Becher, Eugen Trinka, Wolfgang Hitzl, Peter Wipfler, Andrea Harrer
Interactions of brain, blood, and CSF: a novel mathematical model of cerebral edema
Omer Doron, Yuliya Zadka, Ofer Barnea, Guy Rosenthal
Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays
Claire Simonneau, Martina Duschmalé, Alina Gavrilov, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Evodie Lassalle, Elena Kassianidou, Hendrik Knoetgen, Jens Niewoehner, Roberto Villaseñor
Activation of Frizzled-7 attenuates blood–brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice
Wei He, Qin Lu, Prativa Sherchan, Lei Huang, Xin Hu, John H. Zhang, Haibin Dai, Jiping Tang
SCO-spondin, a giant matricellular protein that regulates cerebrospinal fluid activity
Vania Sepúlveda, Felipe Maurelia, Maryori González, Jaime Aguayo, Teresa Caprile
Adjunctive cytoprotective therapies in acute ischemic stroke: a systematic review
I. A. Mulder, E. T. van Bavel, H. E. de Vries, J. M. Coutinho
Tachycardia and hypertension enhance tracer efflux from the spinal cord
Shinuo Liu, Lynne E. Bilston, Marcus A. Stoodley, Sarah J. Hemley
Influence of traumatic brain injury on extracellular tau elimination at the blood–brain barrier
Maxwell Eisenbaum, Andrew Pearson, Arissa Gratkowski, Benoit Mouzon, Michael Mullan, Fiona Crawford, Joseph Ojo, Corbin Bachmeier
A novel model of acquired hydrocephalus for evaluation of neurosurgical treatments
James P. McAllister II, Michael R. Talcott, Albert M. Isaacs, Sarah H. Zwick, Maria Garcia-Bonilla, Leandro Castaneyra-Ruiz, Alexis L. Hartman, Ryan N. Dilger, Stephen A. Fleming, Rebecca K. Golden, Diego M. Morales, Carolyn A. Harris, David D. Limbrick Jr
The impact of chronic mild hypoxia on cerebrovascular remodelling; uncoupling of angiogenesis and vascular breakdown
Sebok K. Halder, Richard Milner
Physical exercise and goal attainment after shunt surgery in idiopathic normal pressure hydrocephalus: a randomised clinical trial
Johanna Rydja, Lena Kollén, Per Hellström, Katarina Owen, Åsa Lundgren Nilsson, Carsten Wikkelsø, Mats Tullberg, Fredrik Lundin
Microdialysis and microperfusion electrodes in neurologic disease monitoring
Luke A. Stangler, Abbas Kouzani, Kevin E. Bennet, Ludovic Dumee, Michael Berk, Gregory A. Worrell, Steven Steele, Terence C. Burns, Charles L. Howe
Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis
Rosanna Herold, René Scholtysik, Selina Moroniak, Christel Weiss, Hiroshi Ishikawa, Horst Schroten, Christian Schwerk
Elevated CSF inflammatory markers in patients with idiopathic normal pressure hydrocephalus do not promote NKCC1 hyperactivity in rat choroid plexus
Sara Diana Lolansen, Nina Rostgaard, Søren Norge Andreassen, Anja Hviid Simonsen, Marianne Juhler, Steen Gregers Hasselbalch, Nanna MacAulay
Quantitative analysis of macroscopic solute transport in the murine brain
Lori A. Ray, Martin Pike, Matthew Simon, Jeffrey J. Iliff, Jeffrey J. Heys
Next-generation in vitro blood–brain barrier models: benchmarking and improving model accuracy
Raleigh M. Linville, Peter C. Searson
Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain
Shene Yi-Shiuan Chiou, Kai Kysenius, Yifan Huang, Mark David Habgood, Liam M. Koehn, Fiona Qiu, Peter J. Crouch, Swati Varshney, Katherine Ganio, Katarzyna Magdalena Dziegielewska, Norman Ruthven Saunders
Modeling ischemic stroke in a triculture neurovascular unit on-a-chip
Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, Maria Pontier, Dhanesh G. Kasi, Xandor M. Spijkers, Charlie Hallard, Gwenaëlle Rabussier, Remko van Vught, Paul Vulto, Helga E. de Vries, Henriëtte L. Lanz
Upright versus supine MRI: effects of body position on craniocervical CSF flow
Marco Muccio, David Chu, Lawrence Minkoff, Neeraj Kulkarni, Brianna Damadian, Raymond V. Damadian, Yulin Ge
Biochemical profile of human infant cerebrospinal fluid in intraventricular hemorrhage and post-hemorrhagic hydrocephalus of prematurity
Ayodamola Otun, Diego M. Morales, Maria Garcia-Bonilla, Seth Goldberg, Leandro Castaneyra-Ruiz, Yan Yan, Albert M. Isaacs, Jennifer M. Strahle, James P. McAllister II, David D. Limbrick Jr