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Erschienen in: Clinical Research in Cardiology 1/2024

04.05.2023 | Original Paper

Procedural success in transaxillary transcatheter aortic valve implantation according to type of transcatheter heart valve: results from the multicenter TAXI registry

verfasst von: Andreas Schaefer, Oliver D. Bhadra, Lenard Conradi, Dirk Westermann, Caroline Kellner, Ole De Backer, Vilhelmas Bajoras, Lars Sondergaard, Waqas T. Qureshi, Nikolaos Kakouros, Summer Aldrugh, Ignacio Amat-Santos, Tsuyoshi Kaneko, Morgan Harloff, Rui Teles, Tiago Nolasco, Jose Pedro Neves, Miguel Abecasis, Nikos Werner, Michael Lauterbach, Jerzy Sacha, Krzysztof Krawczyk, Carlo Trani, Enrico Romagnoli, Antonio Mangieri, Francesco Condello, Ander Regueiro, Salvatore Brugaletta, Fausto Biancari, Matti Niemelä, Francesco Giannini, Marco Toselli, Rossella Ruggiero, Andrea Buono, Diego Maffeo, Francesco Bruno, Federico Conrotto, Fabrizio D’Ascenzo, Mikko Savontaus, Jouni Pykäri, Alfonso Ielasi, Maurizio Tespili, Michele Cimmino, Michele Albanese, Giuseppe Biondi-Zoccai, Nicola Corcione, Alberto Morello, Arturo Giordano

Erschienen in: Clinical Research in Cardiology | Ausgabe 1/2024

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Abstract

Background

Transaxillary (TAx) transcatheter aortic valve implantation (TAVI) is a preferred alternative access in patients ineligible for transfemoral TAVI.

Aims

This study used the Trans-AXillary Intervention (TAXI) registry to compare procedural success according to different types of transcatheter heart valves (THV).

Methods

For the TAXI registry anonymized data of patients treated with TAx-TAVI were collected from 18 centers. Acute procedural, early and 1-month clinical outcomes were adjudicated in accordance with standardized VARC-3 definitions.

Results

From 432 patients, 368 patients (85.3%, SE group) received self-expanding (SE) THV and 64 patients (14.8%, BE group) received balloon-expandable (BE) THV. Imaging revealed lower axillary artery diameters in the SE group (max/min diameter in mm: 8.4/6.6 vs 9.4/6.8 mm; p < 0.001/p = 0.04) but a higher proportion of axillary tortuosity in BE group (62/368, 23.6% vs 26/64, 42.6%; p = 0.004) with steeper aorta-left ventricle (LV) inflow (55° vs 51°; p = 0.002) and left ventricular outflow tract (LVOT)-LV inflow angles (40.0° vs 24.5°; 0.002). TAx-TAVI was more often conducted by right sided axillary artery in the BE group (33/368, 9.0% vs 17/64, 26.6%; p < 0.001). Device success was higher in the SE group (317/368, 86.1% vs 44/64, 68.8%, p = 0.0015). In logistic regression analysis, BE THV were a risk factor for vascular complications and axillary stent implantation.

Conclusions

Both, SE and BE THV can be safely used in TAx-TAVI. However, SE THV were more often used and were associated with a higher rate of device success. While SE THV were associated with lower rates of vascular complications, BE THV were more often used in cases with challenging anatomical circumstances.
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Metadaten
Titel
Procedural success in transaxillary transcatheter aortic valve implantation according to type of transcatheter heart valve: results from the multicenter TAXI registry
verfasst von
Andreas Schaefer
Oliver D. Bhadra
Lenard Conradi
Dirk Westermann
Caroline Kellner
Ole De Backer
Vilhelmas Bajoras
Lars Sondergaard
Waqas T. Qureshi
Nikolaos Kakouros
Summer Aldrugh
Ignacio Amat-Santos
Tsuyoshi Kaneko
Morgan Harloff
Rui Teles
Tiago Nolasco
Jose Pedro Neves
Miguel Abecasis
Nikos Werner
Michael Lauterbach
Jerzy Sacha
Krzysztof Krawczyk
Carlo Trani
Enrico Romagnoli
Antonio Mangieri
Francesco Condello
Ander Regueiro
Salvatore Brugaletta
Fausto Biancari
Matti Niemelä
Francesco Giannini
Marco Toselli
Rossella Ruggiero
Andrea Buono
Diego Maffeo
Francesco Bruno
Federico Conrotto
Fabrizio D’Ascenzo
Mikko Savontaus
Jouni Pykäri
Alfonso Ielasi
Maurizio Tespili
Michele Cimmino
Michele Albanese
Giuseppe Biondi-Zoccai
Nicola Corcione
Alberto Morello
Arturo Giordano
Publikationsdatum
04.05.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Research in Cardiology / Ausgabe 1/2024
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-023-02216-1

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Bei schwerer Aortenstenose und obstruktiver KHK empfehlen die Leitlinien derzeit eine chirurgische Kombi-Behandlung aus Klappenersatz plus Bypass-OP. Diese Empfehlung wird allerdings jetzt durch eine aktuelle Studie infrage gestellt – mit überraschender Deutlichkeit.

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