Erschienen in:
30.11.2023 | Letter to the Editor
rs1801253 Gly/Gly carriage in the ADRB1 gene leads to unbalanced cardiac sympathetic modulation as assessed by spectral analysis of heart rate variability
verfasst von:
E. Grossini, D. De Zanet, D. Apostolo, V. R. Mallela, G. La Rocca, A. Greco, G. Coratza, R. Minisini, M. Pirisi
Erschienen in:
Clinical Autonomic Research
|
Ausgabe 1/2024
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Excerpt
The analysis of heart rate variability (HRV) has long been used as a standard non-invasive method for assessing autonomic nervous system (ANS) functions [
1,
2]. By computerized analysis of an electrocardiographic trace of sufficient length, heart rate components can be extrapolated using two methods: time domain analysis and frequency domain analysis. The values obtained from the analysis of HRV reflect differences in the activity of the two branches of the ANS. In fact, in the presence of parasympathetic activation, an increase in standard deviation of RR intervals (SDNN), root mean square of successive differences between normal heart beats (RMSSD), and HRV values is observed [
3]. Also, high frequency (HF) is taken as an index of modulation of the parasympathetic branch, whereas low frequency (LF) is taken as an index of modulation of the sympathetic branch; therefore, their ratio, namely LF/HF, is considered as indicative of sympathetic to parasympathetic balance [
4]. …
